IL232879A0 - Production method for haploid cells, cells thus produced and their uses - Google Patents
Production method for haploid cells, cells thus produced and their usesInfo
- Publication number
- IL232879A0 IL232879A0 IL232879A IL23287914A IL232879A0 IL 232879 A0 IL232879 A0 IL 232879A0 IL 232879 A IL232879 A IL 232879A IL 23287914 A IL23287914 A IL 23287914A IL 232879 A0 IL232879 A0 IL 232879A0
- Authority
- IL
- Israel
- Prior art keywords
- cells
- methods
- produced
- generating haploid
- generating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Public Health (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11191408.1A EP2599859A1 (en) | 2011-11-30 | 2011-11-30 | Haploid cells |
| US201161565626P | 2011-12-01 | 2011-12-01 | |
| PCT/EP2012/074112 WO2013079670A1 (en) | 2011-11-30 | 2012-11-30 | Haploid cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL232879A0 true IL232879A0 (en) | 2014-07-31 |
Family
ID=45218335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL232879A IL232879A0 (en) | 2011-11-30 | 2014-05-29 | Production method for haploid cells, cells thus produced and their uses |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20140342369A1 (enExample) |
| EP (2) | EP2599859A1 (enExample) |
| JP (1) | JP2015500637A (enExample) |
| KR (1) | KR20140101390A (enExample) |
| CN (1) | CN104024404A (enExample) |
| AU (1) | AU2012343826A1 (enExample) |
| CA (1) | CA2856810A1 (enExample) |
| IL (1) | IL232879A0 (enExample) |
| IN (1) | IN2014KN01374A (enExample) |
| SG (1) | SG11201402350QA (enExample) |
| WO (1) | WO2013079670A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2681310B2 (en) * | 2011-03-02 | 2020-01-22 | Anton Wutz | Mammalian haploid embryonic stem cells |
| WO2015152146A1 (ja) * | 2014-03-31 | 2015-10-08 | 国立大学法人東京医科歯科大学 | １倍体胚性幹細胞の培養方法 |
| CN117431206A (zh) * | 2015-07-29 | 2024-01-23 | 纽约干细胞基金会有限公司 | 单倍体人胚胎干细胞系和体细胞系及其制备方法 |
| EP3472342A1 (en) * | 2016-06-19 | 2019-04-24 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Screening for chemotherapy resistance in human haploid cells |
| EP3491131B1 (en) | 2016-07-29 | 2022-05-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Targeted in situ protein diversification by site directed dna cleavage and repair |
| EP3388530A1 (en) | 2017-04-13 | 2018-10-17 | IMBA-Institut für Molekulare Biotechnologie GmbH | Nucleic acid modification and identification method |
| JP7341891B2 (ja) | 2017-04-13 | 2023-09-11 | イーエムベーアー－インスティテュート フュール モレクラレ バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング | 核酸を修飾して同定する方法 |
| CN108998410B (zh) * | 2017-06-07 | 2020-11-06 | 中国科学院动物研究所 | 蛋白激酶抑制剂在抑制单倍体细胞二倍化中的用途 |
| CN107217042B (zh) * | 2017-07-31 | 2020-03-06 | 江苏东抗生物医药科技有限公司 | 一种生产无岩藻糖基化蛋白的基因工程细胞系及其建立方法 |
| US10626319B1 (en) | 2019-05-17 | 2020-04-21 | King Fahd University Of Petroleum And Minerals | Methods of inhibiting corrosion with a pyrazine corrosion inhibitor |
| US20230313130A1 (en) * | 2020-07-17 | 2023-10-05 | Tohoku University | Trophoblast stem cell-like cells capable of differentiating into placenta-constituting cells, and method for producing same |
| CN118370275B (zh) * | 2024-06-21 | 2024-09-06 | 中国科学院昆明动物研究所 | 一种产生母源性半克隆小鼠的方法 |
| CN118389411A (zh) * | 2024-06-21 | 2024-07-26 | 中国科学院昆明动物研究所 | 一种小鼠双单倍体胚胎干细胞分离建系的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945577A (en) | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| EP1092768A1 (en) | 1999-10-16 | 2001-04-18 | ARTEMIS Pharmaceuticals GmbH | Conditional gene trapping construct for the disruption of genes |
| JP2003514516A (ja) | 1999-10-28 | 2003-04-22 | ユニバーシティ オブ マサチューセッツ | 多能性細胞と細胞株の雌性発生的または雄性発生的産生および分化した細胞と組織を産生するためのその使用 |
| CA2388510A1 (en) | 1999-11-02 | 2001-05-10 | James M. Robl | Use of haploid genomes for genetic diagnosis, modification and multiplication |
| US7074611B2 (en) | 2001-04-27 | 2006-07-11 | Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) | Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof |
| WO2004053078A2 (en) | 2002-12-09 | 2004-06-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | METHODS FOR MODULATING IKKα ACTIVITY |
| PT1572984E (pt) | 2002-12-16 | 2016-06-03 | Technion Res & Dev Foundation | Sistema de cultura para células estaminais embrionárias humanas sem células alimentadoras e sem xeno |
| EP1662005A1 (en) | 2004-11-26 | 2006-05-31 | FrankGen Biotechnologie AG | Enhancer-containing gene trap vectors for random and targeted gene trapping |
| DE602005026221D1 (de) | 2004-11-26 | 2011-03-17 | Frankgen Biotechnologie Ag | Gen-fallen-kassette für eine gerichtete und ungerichtete konditionelle geninaktivierung |
| WO2008033469A1 (en) | 2006-09-15 | 2008-03-20 | Children's Medical Center Corporation | Methods for producing embryonic stem cells from parthenogenetic embryos |
| CN101715485A (zh) * | 2007-04-06 | 2010-05-26 | 国际干细胞公司 | 源于人单性生殖胚泡的患者特异性干细胞系 |
| EP2681310B2 (en) | 2011-03-02 | 2020-01-22 | Anton Wutz | Mammalian haploid embryonic stem cells |
-
2011
- 2011-11-30 EP EP11191408.1A patent/EP2599859A1/en not_active Withdrawn
-
2012
- 2012-11-30 AU AU2012343826A patent/AU2012343826A1/en not_active Abandoned
- 2012-11-30 IN IN1374KON2014 patent/IN2014KN01374A/en unknown
- 2012-11-30 KR KR1020147017705A patent/KR20140101390A/ko not_active Withdrawn
- 2012-11-30 JP JP2014543917A patent/JP2015500637A/ja active Pending
- 2012-11-30 EP EP12791811.8A patent/EP2785832A1/en not_active Withdrawn
- 2012-11-30 US US14/361,655 patent/US20140342369A1/en not_active Abandoned
- 2012-11-30 SG SG11201402350QA patent/SG11201402350QA/en unknown
- 2012-11-30 WO PCT/EP2012/074112 patent/WO2013079670A1/en not_active Ceased
- 2012-11-30 CN CN201280065785.XA patent/CN104024404A/zh active Pending
- 2012-11-30 CA CA2856810A patent/CA2856810A1/en not_active Abandoned
-
2014
- 2014-05-29 IL IL232879A patent/IL232879A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012343826A1 (en) | 2014-06-12 |
| EP2785832A1 (en) | 2014-10-08 |
| SG11201402350QA (en) | 2014-06-27 |
| US20140342369A1 (en) | 2014-11-20 |
| CN104024404A (zh) | 2014-09-03 |
| IN2014KN01374A (enExample) | 2015-10-16 |
| WO2013079670A1 (en) | 2013-06-06 |
| KR20140101390A (ko) | 2014-08-19 |
| CA2856810A1 (en) | 2013-06-06 |
| JP2015500637A (ja) | 2015-01-08 |
| EP2599859A1 (en) | 2013-06-05 |
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