IN2014KN01319A - - Google Patents
Info
- Publication number
- IN2014KN01319A IN2014KN01319A IN1319KON2014A IN2014KN01319A IN 2014KN01319 A IN2014KN01319 A IN 2014KN01319A IN 1319KON2014 A IN1319KON2014 A IN 1319KON2014A IN 2014KN01319 A IN2014KN01319 A IN 2014KN01319A
- Authority
- IN
- India
- Prior art keywords
- formula
- cinacalcet
- pharmaceutically acceptable
- acceptable salts
- ethylamine
- Prior art date
Links
- VDHAWDNDOKGFTD-MRXNPFEDSA-N cinacalcet Chemical compound N([C@H](C)C=1C2=CC=CC=C2C=CC=1)CCCC1=CC=CC(C(F)(F)F)=C1 VDHAWDNDOKGFTD-MRXNPFEDSA-N 0.000 abstract 3
- 229960003315 cinacalcet Drugs 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RUJHATQMIMUYKD-UHFFFAOYSA-N 2-naphthalen-1-ylethanamine Chemical compound C1=CC=C2C(CCN)=CC=CC2=C1 RUJHATQMIMUYKD-UHFFFAOYSA-N 0.000 abstract 1
- QWXKQVIMGVVIBX-UHFFFAOYSA-N 3-[3-(trifluoromethyl)phenyl]propan-1-ol Chemical compound OCCCC1=CC=CC(C(F)(F)F)=C1 QWXKQVIMGVVIBX-UHFFFAOYSA-N 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/14—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups
- C07C209/16—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ20110770A CZ303627B6 (cs) | 2011-11-25 | 2011-11-25 | Zpusob výroby Cinacalcetu |
| PCT/CZ2012/000119 WO2013075679A1 (en) | 2011-11-25 | 2012-11-21 | A method of producing cinacalcet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014KN01319A true IN2014KN01319A (cs) | 2015-10-16 |
Family
ID=47435672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1319KON2014 IN2014KN01319A (cs) | 2011-11-25 | 2012-11-21 |
Country Status (7)
| Country | Link |
|---|---|
| CN (1) | CN103958456B (cs) |
| BR (1) | BR112014012434A2 (cs) |
| CZ (1) | CZ303627B6 (cs) |
| HU (1) | HUP1400341A3 (cs) |
| IL (1) | IL232678A (cs) |
| IN (1) | IN2014KN01319A (cs) |
| WO (1) | WO2013075679A1 (cs) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011068A (en) | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5504253A (en) | 1994-07-15 | 1996-04-02 | Nps Pharmaceuticals, Inc. | Amine preparation |
| KR100293621B1 (ko) | 1994-10-21 | 2001-11-26 | 젠센, 제임스 유. | 칼슘수용체-활성화합물 |
| WO2006125026A2 (en) * | 2005-05-16 | 2006-11-23 | Teva Pharmaceutical Industries, Ltd. | Process for preparing cinacalcet hydrochloride |
| WO2006127933A1 (en) * | 2005-05-23 | 2006-11-30 | Teva Pharmaceutical Industries Ltd. | Processes for preparing cinacalcet hydrochloride crystal form i |
| ATE447546T1 (de) | 2006-04-27 | 2009-11-15 | Teva Pharma | Verfahren zur herstellung einer cinacalcetbase |
| KR20080011320A (ko) | 2006-04-27 | 2008-02-01 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 염기의 제조 방법 |
| JP2009539823A (ja) | 2006-06-08 | 2009-11-19 | メディチェム エセ．ア． | シナカルセットの調製のために有用な中間体化合物を調製するためのプロセス |
| CA2691196C (en) * | 2007-06-21 | 2016-05-24 | Amgen Inc. | Methods of synthesizing cinacalcet and salts thereof |
| EP2358659B1 (en) * | 2008-10-28 | 2012-12-26 | ZaCh System S.p.A. | Process for preparing cinacalcet |
-
2011
- 2011-11-25 CZ CZ20110770A patent/CZ303627B6/cs not_active IP Right Cessation
-
2012
- 2012-11-21 WO PCT/CZ2012/000119 patent/WO2013075679A1/en not_active Ceased
- 2012-11-21 HU HU1400341A patent/HUP1400341A3/hu unknown
- 2012-11-21 CN CN201280057515.4A patent/CN103958456B/zh active Active
- 2012-11-21 BR BR112014012434A patent/BR112014012434A2/pt not_active IP Right Cessation
- 2012-11-21 IN IN1319KON2014 patent/IN2014KN01319A/en unknown
-
2014
- 2014-05-18 IL IL232678A patent/IL232678A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN103958456B (zh) | 2015-10-21 |
| WO2013075679A1 (en) | 2013-05-30 |
| IL232678A0 (en) | 2014-08-03 |
| CZ2011770A3 (cs) | 2013-01-16 |
| CN103958456A (zh) | 2014-07-30 |
| CZ303627B6 (cs) | 2013-01-16 |
| HUP1400341A2 (en) | 2014-10-28 |
| IL232678A (en) | 2017-05-29 |
| BR112014012434A2 (pt) | 2017-06-06 |
| HUP1400341A3 (en) | 2014-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014007674A2 (pt) | método para produzir derivados de 4,4-diflúor-3,4-dihidroisoquinolina | |
| TN2013000347A1 (en) | Production method of optically active dihydrobenzofuran derivative | |
| UY32296A (es) | Nuevos compuestos | |
| AR076027A1 (es) | Metodos e intermediarios para la preparacion de agentes farmaceuticos | |
| BR112014001418A2 (pt) | compostos, processo para a preparação dos compostos, e, uso dos compostos | |
| BRPI1006534A2 (pt) | sal do composto 1, processo para preparar um sal do composto 1, e processo para preparar um sal misto do composto 1 | |
| SG10201804021TA (en) | Methods of preparing inhibitors of influenza viruses replication | |
| MX359825B (es) | Compuesto pirazol y su uso farmaceutico. | |
| BR112013032690A2 (pt) | método para produzir um composto, composto, e, uso do mesmo | |
| FR2975990B1 (fr) | Procede de preparation d'un compose organique fluore | |
| HK1205095A1 (en) | Methods and intermediates for preparing pharmaceutical agents | |
| JO2930B1 (en) | A new process for the synthesis of ivabradine and salts of addition with a pharmaceutically acceptable acid | |
| CL2014002029A1 (es) | Método para preparar un compuesto de formula 1 mediante la reacción de adición de michael , usando agua o acido o una mezcla de los mismos como aditivo, entre un compuesto de formula 2 y un compuesto de formula 3 en presencia de polvo de cobre. | |
| IN2014KN01319A (cs) | ||
| JO3189B1 (ar) | طريقة جديدة لتخليق (e2) -3- (3, 4- داي ميثوكسي فينيل)بروب-2 - يننيتريل واستخدامها لتخليق ايفابرادين والاملاح المضافة منها مع حمض مقبول صيدلانيا | |
| UA111329C2 (uk) | Спосіб синтезу івабрадину і його адитивних солей з фармацевтично прийнятною кислотою | |
| ES2556470T3 (es) | Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiazolidiniliden]cianamida | |
| UA117900C2 (uk) | Спосіб синтезу 3-(2-бром-4,5-диметоксифеніл)пропаннітрилу та застосування в синтезі івабрадину та його адитивних солей з фармацевтично прийнятною кислотою | |
| IN2014DE01203A (cs) | ||
| BR112013015903A2 (pt) | polimorfo cristalino, processo para preparar um polimorfo, composição farmacêutica, forma purificada do polimorfo, uso de um polimorfo, processo para preparar um composto, e, composto. | |
| MX2013002656A (es) | Nuevo proceso. | |
| UA111156C2 (uk) | Спосіб синтезу івабрадину і його адитивних солей з фармацевтично прийнятною кислотою | |
| MX2013011705A (es) | Nuevo procedimiento de sintesis del 3-(2-bromo-4,5-dimetoxifenil)p ropanonitrilo, y aplicacion a la sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable. | |
| WO2015092809A3 (en) | Fingolimod hydrochloride process | |
| MX2014003770A (es) | Tetrahidrato de la sal de l-arginina del acido s-(-)-9-fluoro-6,7-dihidro-8-(4-hidroxipiperidin-1-il)-5-metil-1- oxo-1h,5h-benzo[i,j] quinolizin-2-carboxilico puro, y un proceso para su preparacion. |