IN2014KN01308A - - Google Patents

Info

Publication number
IN2014KN01308A
IN2014KN01308A IN1308KON2014A IN2014KN01308A IN 2014KN01308 A IN2014KN01308 A IN 2014KN01308A IN 1308KON2014 A IN1308KON2014 A IN 1308KON2014A IN 2014KN01308 A IN2014KN01308 A IN 2014KN01308A
Authority
IN
India
Prior art keywords
salts
vardenafil
acids
water
isolation
Prior art date
Application number
Other languages
English (en)
Inventor
Ales Halama
Ivo Strelec
Ondrej Dammer
Original Assignee
Zentiva Ks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva Ks filed Critical Zentiva Ks
Publication of IN2014KN01308A publication Critical patent/IN2014KN01308A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Gynecology & Obstetrics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN1308KON2014 2011-11-24 2012-11-26 IN2014KN01308A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20110767A CZ2011767A3 (cs) 2011-11-24 2011-11-24 Zpusob prípravy a izolace solí vardenafilu s kyselinami
PCT/CZ2012/000120 WO2013075680A1 (en) 2011-11-24 2012-11-26 A method for the preparation and isolation of salts of vardenafil with acids

Publications (1)

Publication Number Publication Date
IN2014KN01308A true IN2014KN01308A (ko) 2015-10-16

Family

ID=47435673

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1308KON2014 IN2014KN01308A (ko) 2011-11-24 2012-11-26

Country Status (7)

Country Link
CN (1) CN103946225B (ko)
BR (1) BR112014012430A2 (ko)
CZ (1) CZ2011767A3 (ko)
HU (1) HUP1400334A3 (ko)
IL (1) IL232652A (ko)
IN (1) IN2014KN01308A (ko)
WO (1) WO2013075680A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160317542A1 (en) 2013-12-09 2016-11-03 Respira Therapeutics, Inc. Pde5 inhibitor powder formulations and methods relating thereto
PL223869B1 (pl) 2013-12-16 2016-11-30 Starogardzkie Zakłady Farm Polpharma Spółka Akcyjna Sposób otrzymywania wardenafilu i jego soli
CN107445964A (zh) * 2017-07-29 2017-12-08 合肥创新医药技术有限公司 一种盐酸伐地那非杂质的合成方法
CN111655229A (zh) 2017-12-20 2020-09-11 卡里亚制药控股有限公司 包含伐地那非的薄膜制剂、其制备方法及其用途
CN113166157A (zh) * 2018-11-28 2021-07-23 托帕杜制药公司 新型双作用模式可溶性鸟苷酸环化酶活化剂和磷酸二酯酶抑制剂及其用途
CN114085225A (zh) * 2021-06-04 2022-02-25 广东西捷药业有限公司 一种伐地那非类似物及其合成方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295436A1 (de) * 1997-11-12 2011-03-16 Bayer Schering Pharma AG 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren
DE10063108A1 (de) 2000-12-18 2002-06-20 Bayer Ag Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
DE102004023069A1 (de) 2004-05-11 2005-12-08 Bayer Healthcare Ag Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
US7977478B2 (en) * 2006-03-13 2011-07-12 Dr. Reddy's Laboratories Limited Polymorphic forms of vardenafil
DE102007027067A1 (de) 2007-06-12 2008-12-18 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat
WO2009030095A1 (en) 2007-09-06 2009-03-12 Topharman Shanghai Co., Ltd. Process for preparing vardenafil and its intermediates
WO2009082845A1 (en) 2007-12-28 2009-07-09 Topharman Shanghai Co., Ltd. N-{1-[3-(2-ethoxy-5-(4-ethylpiperazinyl)benzenesulfonyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl}butyramide, the preparation method and use thereof
DE102009020888A1 (de) 2009-05-12 2010-11-18 Ratiopharm Gmbh Schmelztablette, enthaltend ein Vardenafil-Salz
PL390079A1 (pl) * 2009-12-30 2011-07-04 Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna Sposób otrzymywania wardenafilu i jego izolacji jako soli z kwasem cytrynowym oraz krystaliczna postać tej soli
CN101870698B (zh) * 2010-04-02 2012-10-17 漆又毛 磺酰苯基咪唑并三嗪衍生物及制备方法

Also Published As

Publication number Publication date
CN103946225A (zh) 2014-07-23
BR112014012430A2 (pt) 2017-06-06
CZ303877B6 (cs) 2013-06-05
HUP1400334A2 (hu) 2014-10-28
CZ2011767A3 (cs) 2013-06-05
IL232652A0 (en) 2014-06-30
WO2013075680A1 (en) 2013-05-30
HUP1400334A3 (en) 2014-12-29
CN103946225B (zh) 2016-06-15
IL232652A (en) 2017-05-29

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