IN2014KN01026A - - Google Patents
Info
- Publication number
- IN2014KN01026A IN2014KN01026A IN1026KON2014A IN2014KN01026A IN 2014KN01026 A IN2014KN01026 A IN 2014KN01026A IN 1026KON2014 A IN1026KON2014 A IN 1026KON2014A IN 2014KN01026 A IN2014KN01026 A IN 2014KN01026A
- Authority
- IN
- India
- Prior art keywords
- formation
- inducing
- cartilage
- capability
- bone
- Prior art date
Links
- 230000001939 inductive effect Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 101100175316 Mus musculus Gdf5 gene Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 230000022159 cartilage development Effects 0.000 abstract 1
- 230000007547 defect Effects 0.000 abstract 1
- 230000011164 ossification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11191973.4A EP2602264A1 (de) | 2011-12-05 | 2011-12-05 | GDF-5-Mutant zur Induzierung der Knorpelbildung |
| PCT/EP2012/074549 WO2013083649A1 (en) | 2011-12-05 | 2012-12-05 | Gdf-5 mutant for inducing cartilage formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014KN01026A true IN2014KN01026A (de) | 2015-10-09 |
Family
ID=47278877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1026KON2014 IN2014KN01026A (de) | 2011-12-05 | 2012-12-05 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9718867B2 (de) |
| EP (3) | EP2602264A1 (de) |
| JP (1) | JP6185926B2 (de) |
| KR (1) | KR102067724B1 (de) |
| CN (1) | CN104039820B (de) |
| AU (1) | AU2012347305B2 (de) |
| BR (1) | BR112014013122A2 (de) |
| CA (1) | CA2856458C (de) |
| DK (2) | DK2788374T3 (de) |
| EA (1) | EA028554B1 (de) |
| ES (2) | ES2630853T3 (de) |
| HR (2) | HRP20170205T1 (de) |
| HU (2) | HUE033025T2 (de) |
| IN (1) | IN2014KN01026A (de) |
| LT (2) | LT3168230T (de) |
| MX (1) | MX351809B (de) |
| PL (2) | PL2788374T3 (de) |
| PT (2) | PT2788374T (de) |
| RS (2) | RS58253B1 (de) |
| SI (2) | SI3168230T1 (de) |
| TR (1) | TR201901263T4 (de) |
| WO (1) | WO2013083649A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101639269B1 (ko) | 2015-12-02 | 2016-07-13 | 주식회사 셀루메드 | 알칼라인 포스파타아제 어세이를 개선하기 위한 방법 |
| JP7700127B2 (ja) * | 2019-12-18 | 2025-06-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 疼痛及び軟骨破壊を治療するためのｇｄｆ－５変異体の使用 |
| CN111701075A (zh) * | 2020-06-24 | 2020-09-25 | 亘元(天津)生物医药科技有限公司 | 一种软骨修复材料、软骨重建生物支架及制备方法 |
| EP4599842A1 (de) * | 2024-02-09 | 2025-08-13 | Association Institut de Myologie | Pegyliertes gdf5-protein |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1439190A1 (de) | 1993-01-12 | 2004-07-21 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-5 |
| IL110589A0 (en) | 1993-08-10 | 1994-11-11 | Bioph Biotech Entw Pharm Gmbh | Growth/differentiation factor of the TGF- beta family |
| JP3717930B2 (ja) | 1993-12-07 | 2005-11-16 | ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー | Ｂｍｐ−１２、ｂｍｐ−１３およびそれらの腱誘導組成物 |
| AU1120295A (en) | 1994-11-07 | 1996-05-31 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cartilage-derived morphogenetic proteins |
| UA46767C2 (uk) | 1995-04-19 | 2002-06-17 | Біофарм Гезельшафт Цур Біотехнологішен Ентвіклунг Фон Фармака Мбх | Білок, фармацевтична композиція для лікування захворювань хрящів і кісток, спосіб отримання білка, спосіб отримання гомодимерного білка, спосіб лікування захворювань хрящів і кісток |
| JPH0931098A (ja) | 1995-07-24 | 1997-02-04 | Hoechst Japan Ltd | 新規なタンパク質ｈｍｗヒトｍｐ５２ |
| ZA966489B (en) | 1995-08-03 | 1997-02-26 | Bioph Biotech Entw Pharm Gmbh | New protein human MP52 Arg. |
| DE19647853A1 (de) | 1996-11-19 | 1998-05-20 | Bioph Biotech Entw Pharm Gmbh | Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität |
| JPH11335398A (ja) | 1998-05-22 | 1999-12-07 | Hoechst Marion Roussel Kk | 新規な骨誘導活性を有する単量体蛋白質およびそれらからなる軟骨・骨疾患の予防および治療薬 |
| EP1074620A1 (de) | 1999-08-06 | 2001-02-07 | HyGene AG | Monomer Protein der TGF-beta Familie |
| JP2000119192A (ja) | 1998-10-09 | 2000-04-25 | Aventis Pharma Ltd | 骨誘導因子アンタゴニスト活性を有する成熟型蛋白質 |
| DE10026713A1 (de) | 2000-05-30 | 2001-12-06 | Walter Sebald | Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta |
| KR100530299B1 (ko) * | 2003-08-11 | 2005-11-22 | 산도즈 게엠베하 | 변이 세팔로스포린 ｃ 아실라제 및 이를 이용한 7-ａｃａ 제조방법 |
| EP1571159A1 (de) | 2004-03-04 | 2005-09-07 | Bayerische Julius-Maximilians-Universität Würzburg | Mutein von Knochenmorphogenetisches Protein und seine Verwendung |
| EP1698691A1 (de) * | 2005-03-04 | 2006-09-06 | Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH | Mutanten von Wachstumsfaktoren mit verbesserter biologischer Eigenschaft |
| EP1721909A1 (de) | 2005-05-10 | 2006-11-15 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Wachstumsfaktoren mit geänderten biologischen Eigenschaften |
| JP2007054013A (ja) * | 2005-08-26 | 2007-03-08 | Research Institute Of Innovative Technology For The Earth | 耐熱性ｌ−スレオニンアルドラ−ゼおよびそれをコードする遺伝子 |
| EP1948689B1 (de) * | 2005-11-18 | 2012-04-11 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Wachstumsfaktormutanten mit hoher aktivität |
| CN103641916A (zh) | 2006-03-27 | 2014-03-19 | 医学免疫有限公司 | Gm-csf受体结合元件 |
| EP1915986A1 (de) | 2006-10-23 | 2008-04-30 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Wachstumsfaktorhaltige Lipidformulierungen |
| AU2011292810B2 (en) | 2010-08-20 | 2015-04-30 | Wyeth Llc | Designer osteogenic proteins |
-
2011
- 2011-12-05 EP EP11191973.4A patent/EP2602264A1/de not_active Ceased
-
2012
- 2012-12-05 EA EA201491119A patent/EA028554B1/ru not_active IP Right Cessation
- 2012-12-05 ES ES12795011.1T patent/ES2630853T3/es active Active
- 2012-12-05 CA CA2856458A patent/CA2856458C/en active Active
- 2012-12-05 HR HRP20170205TT patent/HRP20170205T1/hr unknown
- 2012-12-05 PL PL12795011T patent/PL2788374T3/pl unknown
- 2012-12-05 CN CN201280058254.8A patent/CN104039820B/zh not_active Expired - Fee Related
- 2012-12-05 LT LTEP16203435.9T patent/LT3168230T/lt unknown
- 2012-12-05 PL PL16203435T patent/PL3168230T3/pl unknown
- 2012-12-05 EP EP16203435.9A patent/EP3168230B1/de active Active
- 2012-12-05 AU AU2012347305A patent/AU2012347305B2/en not_active Ceased
- 2012-12-05 KR KR1020147017053A patent/KR102067724B1/ko not_active Expired - Fee Related
- 2012-12-05 SI SI201231517T patent/SI3168230T1/sl unknown
- 2012-12-05 SI SI201230892A patent/SI2788374T1/sl unknown
- 2012-12-05 RS RS20190038A patent/RS58253B1/sr unknown
- 2012-12-05 HU HUE12795011A patent/HUE033025T2/en unknown
- 2012-12-05 JP JP2014543942A patent/JP6185926B2/ja active Active
- 2012-12-05 HU HUE16203435A patent/HUE042191T2/hu unknown
- 2012-12-05 DK DK12795011.1T patent/DK2788374T3/en active
- 2012-12-05 PT PT127950111T patent/PT2788374T/pt unknown
- 2012-12-05 ES ES16203435T patent/ES2708675T3/es active Active
- 2012-12-05 PT PT16203435T patent/PT3168230T/pt unknown
- 2012-12-05 MX MX2014006465A patent/MX351809B/es active IP Right Grant
- 2012-12-05 US US14/362,691 patent/US9718867B2/en active Active
- 2012-12-05 BR BR112014013122-8A patent/BR112014013122A2/pt not_active Application Discontinuation
- 2012-12-05 TR TR2019/01263T patent/TR201901263T4/tr unknown
- 2012-12-05 RS RS20170146A patent/RS55686B1/sr unknown
- 2012-12-05 DK DK16203435.9T patent/DK3168230T3/en active
- 2012-12-05 IN IN1026KON2014 patent/IN2014KN01026A/en unknown
- 2012-12-05 WO PCT/EP2012/074549 patent/WO2013083649A1/en not_active Ceased
- 2012-12-05 EP EP12795011.1A patent/EP2788374B1/de active Active
- 2012-12-05 LT LTEP12795011.1T patent/LT2788374T/lt unknown
-
2019
- 2019-01-23 HR HRP20190160TT patent/HRP20190160T8/hr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014DN10386A (de) | ||
| TN2012000512A1 (en) | Compositions and methods of use for therapeutic low density lipoprotein - related protein 6 (lrp6) multivalent antibodies | |
| EP2773744A4 (de) | Medienzusammensetzungen zur förderung eines bakterien- und pilzwachstums | |
| SG184222A1 (en) | Derivatives of 1-amino-2-cyclopropylethylboronic acid | |
| MX343640B (es) | Promotor de osteogenesis. | |
| TN2012000511A1 (en) | Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies | |
| BR112014009418A2 (pt) | macrociclos peptidomiméticos | |
| PH12012501680A1 (en) | Compositions and methods for the diagnosis and treatment of tumor | |
| HRP20150117T1 (xx) | Pripravci kolagenaze g i kolagenaze h za lijeäśenje bolesti koje ukljuäśuju promjene kolagena | |
| ZA201403596B (en) | Composition for use in the promotion of healthy bone growth and/or in the prevention and/or treatment of bone disease | |
| PH12014502537A1 (en) | Therapeutic uses of fibroblast growth factor 21 proteins | |
| EP2579936A4 (de) | Magensonde zur behandlung von adipositas | |
| EP3711771C0 (de) | Abschwächung von gewebeverletzungen und fibrose mithilfe des latenten transformierenden wachstumsfaktor-beta-bindenden proteins (ltbp4) | |
| MY163257A (en) | Humanised anti-cd52 antibodies | |
| PH12014501200A1 (en) | Bacteriophage gene 3 protein compositions and use as amyloid binding agents | |
| SMT201600147B (it) | Metodi per migliorare l'espressione di proteine ricombinanti | |
| SG10201900541QA (en) | Derivatives of xanthone compounds | |
| MX359181B (es) | Hidrolizado de colágeno y uso del mismo. | |
| NZ717930A (en) | Compositions for the treatment of hypertension and/or fibrosis | |
| MX2013002121A (es) | Quinolina-3-carboxamidas sustituidas como moduladores de kcnq2/3. | |
| IN2014KN01026A (de) | ||
| IN2014DN00254A (de) | ||
| PH12012501963A1 (en) | Compositions and methods for the diagnosis and treatment of tumor | |
| MX347541B (es) | Analogos de acido sialico. | |
| UY34485A (es) | Inhibidores de la péptido desformilasa |