IN2014DN07149A - - Google Patents
Info
- Publication number
- IN2014DN07149A IN2014DN07149A IN7149DEN2014A IN2014DN07149A IN 2014DN07149 A IN2014DN07149 A IN 2014DN07149A IN 7149DEN2014 A IN7149DEN2014 A IN 7149DEN2014A IN 2014DN07149 A IN2014DN07149 A IN 2014DN07149A
- Authority
- IN
- India
- Prior art keywords
- antibodies
- diagnosis
- treatment
- present application
- application discloses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0058—Antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1018—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261591835P | 2012-01-27 | 2012-01-27 | |
| US201261711207P | 2012-10-08 | 2012-10-08 | |
| PCT/US2013/023307 WO2013112945A1 (en) | 2012-01-27 | 2013-01-25 | Humanized antibodies that recognize alpha-synuclein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN07149A true IN2014DN07149A (es) | 2015-04-24 |
Family
ID=48873980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN7149DEN2014 IN2014DN07149A (es) | 2012-01-27 | 2013-01-25 |
Country Status (23)
| Country | Link |
|---|---|
| US (7) | US8790644B2 (es) |
| EP (1) | EP2807188B1 (es) |
| JP (2) | JP6342333B2 (es) |
| KR (2) | KR102246217B1 (es) |
| CN (2) | CN104619724B (es) |
| AU (1) | AU2013211874B2 (es) |
| BR (1) | BR112014018561A8 (es) |
| CA (1) | CA2863953A1 (es) |
| CL (1) | CL2014001984A1 (es) |
| DK (1) | DK2807188T3 (es) |
| ES (1) | ES2749457T3 (es) |
| HK (1) | HK1204791A1 (es) |
| IL (2) | IL233829B (es) |
| IN (1) | IN2014DN07149A (es) |
| MX (2) | MX360778B (es) |
| MY (1) | MY171140A (es) |
| NZ (1) | NZ629296A (es) |
| PH (1) | PH12014501685A1 (es) |
| RU (1) | RU2642262C2 (es) |
| SG (1) | SG11201404321YA (es) |
| UA (1) | UA115439C2 (es) |
| WO (1) | WO2013112945A1 (es) |
| ZA (1) | ZA201406227B (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104334184B (zh) | 2011-10-28 | 2017-12-29 | 普罗典娜生物科学有限公司 | 识别α‑突触核蛋白的人源化抗体 |
| AU2013211874B2 (en) | 2012-01-27 | 2017-11-02 | Prothena Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| US10513555B2 (en) | 2013-07-04 | 2019-12-24 | Prothena Biosciences Limited | Antibody formulations and methods |
| WO2015001085A1 (en) * | 2013-07-05 | 2015-01-08 | Genmab B.V. | Humanized or chimeric cd3 antibodies |
| CN111499743B (zh) * | 2013-11-21 | 2024-01-12 | 豪夫迈·罗氏有限公司 | 抗-α-突触核蛋白抗体及使用方法 |
| CA2944402A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| JP2017536102A (ja) | 2014-10-16 | 2017-12-07 | ジェネンテック， インコーポレイテッド | 抗アルファ−シヌクレイン抗体及び使用方法 |
| CN106568969B (zh) * | 2016-10-19 | 2017-09-26 | 首都医科大学 | 一种丝氨酸129位磷酸化alpha‑突触核蛋白聚集体的ELISA检测方法 |
| CA3042302A1 (en) | 2016-12-02 | 2018-06-07 | Prothena Biosciences Limited | Infrared assay detecting secondary structure profiles of alpha-synuclein |
| CN110506057B (zh) * | 2017-02-17 | 2023-09-29 | 百时美施贵宝公司 | Alpha突触核蛋白抗体及其应用 |
| EP3406632A1 (en) | 2017-05-23 | 2018-11-28 | S.I.S.S.A. Scuola Internazionale Superiore di Studi Avanzati | Ligands binding to prion protein for use in the treatment of synucleinopathies |
| EP3725806A4 (en) * | 2017-12-14 | 2022-03-30 | ABL Bio Inc. | BISPECIFIC ANTIBODIES AGAINST A-SYN/IGF1R AND ASSOCIATED USE |
| GB201720975D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Anti-alpha synuclein antibodies |
| GB201720970D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Antibodies |
| US11505610B2 (en) | 2018-04-06 | 2022-11-22 | Atyr Pharma, Inc. | Compositions and methods comprising anti-NRP2 antibodies |
| JP2021534381A (ja) | 2018-08-09 | 2021-12-09 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | パーキンソン病の判定 |
| CA3111907A1 (en) * | 2018-10-19 | 2020-04-23 | Janssen Vaccines & Prevention B.V. | Anti-synuclein antibodies |
| EP4037711A4 (en) * | 2019-10-03 | 2024-02-14 | Atyr Pharma Inc | COMPOSITIONS AND METHODS USING ANTI-NRP2 ANTIBODIES |
| PE20230078A1 (es) | 2020-04-24 | 2023-01-11 | Hoffmann La Roche | Modulacion de enzimas y vias con compuestos de sulfhidrilo y sus derivados |
| EP4185612A1 (en) * | 2020-07-23 | 2023-05-31 | Othair Prothena Limited | Anti-abeta antibodies |
| CN113912714B (zh) * | 2021-12-15 | 2022-02-22 | 北京凯祥弘康生物科技有限公司 | 特异性结合α-突触核蛋白的抗体及其应用 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2 Inc | Geänderte antikörper. |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| IE64738B1 (en) | 1990-03-20 | 1995-09-06 | Akzo Nv | Stabilized gonadotropin containing preparations |
| LU91067I2 (fr) | 1991-06-14 | 2004-04-02 | Genentech Inc | Trastuzumab et ses variantes et dérivés immuno chimiques y compris les immotoxines |
| US5786464C1 (en) | 1994-09-19 | 2012-04-24 | Gen Hospital Corp | Overexpression of mammalian and viral proteins |
| EP0820299B1 (en) | 1995-02-06 | 2002-04-24 | Genetics Institute, Inc. | Formulations for il-12 |
| DE19539493A1 (de) | 1995-10-24 | 1997-04-30 | Thomae Gmbh Dr K | Starker homologer Promotor aus Hamster |
| US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6114148C1 (en) | 1996-09-20 | 2012-05-01 | Gen Hospital Corp | High level expression of proteins |
| US5888809A (en) | 1997-05-01 | 1999-03-30 | Icos Corporation | Hamster EF-1α transcriptional regulatory DNA |
| CN100489892C (zh) | 1999-02-05 | 2009-05-20 | 三星电子株式会社 | 恢复描述图像的纹理特征的图像纹理描述符的方法及装置 |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| JP2005532825A (ja) | 2002-05-13 | 2005-11-04 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | ベネズエラウマ脳炎ウイルスに対するヒト化抗体 |
| US8506959B2 (en) | 2002-11-01 | 2013-08-13 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
| US9034337B2 (en) * | 2003-10-31 | 2015-05-19 | Prothena Biosciences Limited | Treatment and delay of outset of synucleinopathic and amyloidogenic disease |
| US20080014194A1 (en) | 2003-10-31 | 2008-01-17 | Elan Pharmaceuticals, Inc. | Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease |
| TW200509968A (en) | 2002-11-01 | 2005-03-16 | Elan Pharm Inc | Prevention and treatment of synucleinopathic disease |
| CA2507664C (en) | 2002-11-29 | 2010-09-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product |
| PL2335725T3 (pl) | 2003-04-04 | 2017-04-28 | Genentech, Inc. | Preparaty zawierające wysokoskoncentrowane przeciwciała i białka |
| US7358331B2 (en) | 2003-05-19 | 2008-04-15 | Elan Pharmaceuticals, Inc. | Truncated fragments of alpha-synuclein in Lewy body disease |
| DE10338531A1 (de) | 2003-08-19 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Reklonierung von Produktionszellen |
| US7674599B2 (en) * | 2003-11-08 | 2010-03-09 | Elan Pharmaceuticals, Inc. | Methods of using antibodies to detect alpha-synuclein in fluid samples |
| EP2221315A1 (en) * | 2003-12-04 | 2010-08-25 | Xencor, Inc. | Methods of generating variant proteins with increased host string content and compositions thereof |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| DE602005014805D1 (de) | 2004-11-10 | 2009-07-16 | Boehringer Ingelheim Pharma | Verwendung von durchflusszytometrischer analyse zur optimierung von zellbankingstrategien für cho-zellen |
| US7930064B2 (en) * | 2004-11-19 | 2011-04-19 | Parata Systems, Llc | Automated drug discrimination during dispensing |
| CA2657953A1 (en) | 2005-07-19 | 2007-01-25 | University Of Rochester | Alpha-synuclein antibodies and methods related thereto |
| CA2657681C (en) | 2006-07-14 | 2019-03-19 | Ac Immune S.A. | Humanized antibodies against beta amyloid protein |
| US20080124760A1 (en) | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
| LT2436696T (lt) * | 2007-01-05 | 2017-08-25 | University Of Zurich | Anti-beta-amiloido antikūnas ir jo panaudojimas |
| CA2678863A1 (en) | 2007-02-23 | 2008-08-28 | Schering Corporation | Engineered anti-il-23p19 antibodies |
| US8147833B2 (en) | 2007-02-23 | 2012-04-03 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
| DK3067066T3 (da) | 2007-02-23 | 2019-05-20 | Prothena Biosciences Ltd | Forebyggelse og behandling af synukleinopatisk og amyloidogenisk sygdom |
| EP2522730A1 (en) | 2007-03-02 | 2012-11-14 | Boehringer Ingelheim Pharma GmbH & Co. KG | Improvement of protein production |
| US8071097B2 (en) | 2007-03-22 | 2011-12-06 | Genentech, Inc. | Apoptotic anti-IgE antibodies |
| KR20090113340A (ko) | 2007-03-22 | 2009-10-29 | 임클론 엘엘씨 | 안정한 항체 제제 |
| EP2031064A1 (de) | 2007-08-29 | 2009-03-04 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verfahren zur Steigerung von Proteintitern |
| WO2009080541A1 (en) | 2007-12-21 | 2009-07-02 | F. Hoffmann-La Roche Ag | Antibody formulation |
| EA036059B1 (ru) | 2007-12-28 | 2020-09-21 | Протена Байосайенсиз Лимитед | Способ получения антитела или его фрагмента, которое специфически связывается с агрегированным амилоидным белком |
| AT506535B1 (de) * | 2008-02-22 | 2010-04-15 | Affiris Forschungs & Entwicklungs Gmbh | Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden |
| ES2709048T3 (es) | 2008-04-29 | 2019-04-15 | Bioarctic Ab | Anticuerpos y vacunas para su uso en métodos terapéuticos y diagnósticos para trastornos relacionados con alfasinucleína |
| WO2009141239A1 (en) | 2008-05-20 | 2009-11-26 | F. Hoffmann-La Roche Ag | A pharmaceutical formulation comprising an antibody against ox40l, uses thereof |
| US20120276019A1 (en) | 2008-07-25 | 2012-11-01 | Diamedica Inc. | Tissue kallikrein for the treatment of parkinson's disease |
| DE102008048129A1 (de) | 2008-09-20 | 2010-04-22 | Lfk-Lenkflugkörpersysteme Gmbh | Flugkörper mit zumindest einem Bremsfallschirm sowie Befestigungsvorrichtung zur Befestigung eines Bremsfallschirms an einem Flugkörper |
| JP5810413B2 (ja) | 2008-12-19 | 2015-11-11 | バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー | ヒト抗アルファシヌクレイン自己抗体 |
| ES2887552T3 (es) | 2009-07-28 | 2021-12-23 | Takeda Pharmaceuticals Co | Composiciones y métodos para tratar la enfermedad de Gaucher |
| AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
| EP2519537A4 (en) | 2009-12-29 | 2013-07-10 | Reddys Lab Ltd Dr | CLEANING PROTEINS |
| EP2366714A1 (en) | 2010-03-03 | 2011-09-21 | Dr. Rentschler Holding GmbH & Co. KG | Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein |
| TW201134488A (en) | 2010-03-11 | 2011-10-16 | Ucb Pharma Sa | PD-1 antibodies |
| EP2560994B1 (en) * | 2010-04-08 | 2016-10-12 | JN Biosciences LLC | Antibodies to cd122 |
| AU2011265054B2 (en) * | 2010-06-08 | 2016-09-15 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
| TWI629483B (zh) * | 2010-06-11 | 2018-07-11 | 協和醱酵麒麟有限公司 | anti-TIM-3 antibody |
| CA2805112A1 (en) * | 2010-07-15 | 2012-01-19 | Synovex Corporation | Humanized antibodies targeting the ec1 domain of cadherin-11 and related compositions and methods |
| AU2011316730B2 (en) | 2010-10-11 | 2015-12-10 | Abbvie Bahamas Ltd. | Processes for purification of proteins |
| US20140050733A1 (en) | 2011-02-07 | 2014-02-20 | Dale B. Schenk | Apoe immunotherapy |
| WO2012160536A1 (en) | 2011-05-26 | 2012-11-29 | Dr Reddy's Laboratories Limited | Antibody purification |
| JP6061922B2 (ja) | 2011-06-22 | 2017-01-18 | ザ ジェネラル ホスピタル コーポレイション | プロテイノパチーの処置方法 |
| CN107090038A (zh) | 2011-06-30 | 2017-08-25 | 霍夫曼-拉罗奇有限公司 | 抗c‑met抗体配制剂 |
| CN104334184B (zh) | 2011-10-28 | 2017-12-29 | 普罗典娜生物科学有限公司 | 识别α‑突触核蛋白的人源化抗体 |
| CA3078979C (en) | 2011-10-31 | 2022-10-11 | Genentech, Inc. | Formulation comprising an anti-il13 antibody having extended stability |
| AU2013211874B2 (en) | 2012-01-27 | 2017-11-02 | Prothena Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| EP2890712B1 (en) | 2012-08-29 | 2019-05-01 | F.Hoffmann-La Roche Ag | Blood brain barrier shuttle |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| US10513555B2 (en) | 2013-07-04 | 2019-12-24 | Prothena Biosciences Limited | Antibody formulations and methods |
| CA2944402A1 (en) | 2014-04-08 | 2015-10-15 | Prothena Biosciences Limited | Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein |
| US10084674B2 (en) | 2015-09-09 | 2018-09-25 | International Business Machines Corporation | Virtual desktop operation and data continuity preservation |
-
2013
- 2013-01-25 AU AU2013211874A patent/AU2013211874B2/en not_active Ceased
- 2013-01-25 CN CN201380007018.8A patent/CN104619724B/zh not_active Expired - Fee Related
- 2013-01-25 KR KR1020207006200A patent/KR102246217B1/ko active IP Right Grant
- 2013-01-25 CA CA2863953A patent/CA2863953A1/en not_active Abandoned
- 2013-01-25 US US13/750,983 patent/US8790644B2/en not_active Expired - Fee Related
- 2013-01-25 DK DK13740871.2T patent/DK2807188T3/da active
- 2013-01-25 KR KR1020147024060A patent/KR102086061B1/ko active IP Right Grant
- 2013-01-25 CN CN201810297949.0A patent/CN108517010A/zh active Pending
- 2013-01-25 RU RU2014134747A patent/RU2642262C2/ru active
- 2013-01-25 WO PCT/US2013/023307 patent/WO2013112945A1/en active Application Filing
- 2013-01-25 UA UAA201409460A patent/UA115439C2/uk unknown
- 2013-01-25 BR BR112014018561A patent/BR112014018561A8/pt active Search and Examination
- 2013-01-25 IN IN7149DEN2014 patent/IN2014DN07149A/en unknown
- 2013-01-25 ES ES13740871T patent/ES2749457T3/es active Active
- 2013-01-25 SG SG11201404321YA patent/SG11201404321YA/en unknown
- 2013-01-25 EP EP13740871.2A patent/EP2807188B1/en active Active
- 2013-01-25 MY MYPI2014002199A patent/MY171140A/en unknown
- 2013-01-25 JP JP2014554890A patent/JP6342333B2/ja not_active Expired - Fee Related
- 2013-01-25 MX MX2014008952A patent/MX360778B/es active IP Right Grant
- 2013-01-25 NZ NZ629296A patent/NZ629296A/en not_active IP Right Cessation
-
2014
- 2014-07-24 US US14/340,342 patent/US9234031B2/en not_active Expired - Fee Related
- 2014-07-24 PH PH12014501685A patent/PH12014501685A1/en unknown
- 2014-07-24 US US14/340,355 patent/US9217030B2/en not_active Expired - Fee Related
- 2014-07-24 MX MX2018014044A patent/MX2018014044A/es unknown
- 2014-07-25 CL CL2014001984A patent/CL2014001984A1/es unknown
- 2014-07-27 IL IL233829A patent/IL233829B/en active IP Right Grant
- 2014-08-25 ZA ZA2014/06227A patent/ZA201406227B/en unknown
-
2015
- 2015-06-03 HK HK15105305.2A patent/HK1204791A1/xx unknown
- 2015-11-10 US US14/937,792 patent/US9670273B2/en active Active
-
2017
- 2017-05-04 US US15/587,255 patent/US10118960B2/en not_active Expired - Fee Related
-
2018
- 2018-05-16 JP JP2018094968A patent/JP6807893B2/ja active Active
- 2018-09-27 US US16/144,923 patent/US10597441B2/en not_active Expired - Fee Related
-
2020
- 2020-02-19 US US16/795,479 patent/US10875909B2/en active Active
-
2021
- 2021-03-22 IL IL281731A patent/IL281731A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014DN07149A (es) | ||
| MX2019014658A (es) | Anticuerpos humanizados que reconocen la alfa-sinucleina. | |
| GEP20217263B (en) | Anti-cd27 antibodies | |
| MX2016003129A (es) | Terapia de combinacion de anticuerpos contra el csf-1r humano y anticuerpos contralel pd-l1 humano. | |
| EA201591198A1 (ru) | Антитела к gdf15 | |
| PH12015500114B1 (en) | HUMAN ANTIBODIES TO GFRa3 AND METHODS OF USE THEREOF | |
| EA201791186A1 (ru) | Антитела к cd38 | |
| UA107827C2 (en) | Antibody cd40 | |
| EA201491541A1 (ru) | АНТИТЕЛА ПРОТИВ ИНТЕГРИНОВ αvβ6 И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ ЗЛОКАЧЕСТВЕННЫХ НОВООБРАЗОВАНИЙ | |
| EP2955195A4 (en) | ANTI-SEMAPHORIN-3A ANTIBODY AND TREATMENT OF ALZHEIMER AND INFLAMMATORY IMMUNE DISEASES THEREWITH | |
| EP3010938A4 (en) | Fcrn-specific human antibody and composition for treatment of autoimmune diseases | |
| MY164579A (en) | Safe and functional humanized antibodies | |
| MX2015011772A (es) | Anticuerpos anti-hepcidina y usos de los mismos. | |
| EP2694530A4 (en) | NOVEL PEPTIDES THAT BIND TYPES OF CLASS II MAJOR HISTOCOMPATIBILITY COMPLEX AND THEIR USE FOR DIAGNOSIS AND TREATMENT | |
| HK1258028A1 (zh) | 人類抗體及其在神經疾病治療中的診斷和治療用途 | |
| EP2700652A4 (en) | DIAGNOSIS AND TREATMENT OF CANCER BY ANTI-ITM2A ANTIBODIES | |
| EP3628326C0 (en) | METHODS AND SUBSTANCES FOR TREATING PUMP DISEASE | |
| GB201109238D0 (en) | Antibodies | |
| EP2849789A4 (en) | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING TUMORS | |
| EP2563395A4 (en) | TREATMENT WITH ANTI-S1P ANTIBODY OF PATIENTS WITH OCULAR DISEASES | |
| FR2979346B1 (fr) | Nanocorps anti-vcam-1 | |
| EP2569334A4 (en) | RECOMBINANT-PRODUCED ANTIBODIES FOR THE TARGETING OF ERBB SIGNALING MOLECULES AND METHOD FOR THEIR USE FOR DISEASE DIAGNOSIS AND TREATMENT | |
| IL284807A (en) | Antibodies specific for human nectin-2 | |
| HK1216903A1 (zh) | 抗體-尿素酶偶聯物在診斷和治療中的應用 | |
| MX2013009529A (es) | Tratamiento de enfermedad de crohn con fistulas. |