IN2014DN03049A - - Google Patents
Info
- Publication number
- IN2014DN03049A IN2014DN03049A IN3049DEN2014A IN2014DN03049A IN 2014DN03049 A IN2014DN03049 A IN 2014DN03049A IN 3049DEN2014 A IN3049DEN2014 A IN 3049DEN2014A IN 2014DN03049 A IN2014DN03049 A IN 2014DN03049A
- Authority
- IN
- India
- Prior art keywords
- extracellular matrix
- tissue
- interstitial
- expression
- ecm
- Prior art date
Links
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 abstract 3
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 abstract 3
- 210000002744 extracellular matrix Anatomy 0.000 abstract 3
- 210000001519 tissue Anatomy 0.000 abstract 2
- 102000012422 Collagen Type I Human genes 0.000 abstract 1
- 108010022452 Collagen Type I Proteins 0.000 abstract 1
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000002950 fibroblast Anatomy 0.000 abstract 1
- 230000003176 fibrotic effect Effects 0.000 abstract 1
- 230000008595 infiltration Effects 0.000 abstract 1
- 238000001764 infiltration Methods 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 229960003151 mercaptamine Drugs 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 230000002206 pro-fibrotic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 231100000241 scar Toxicity 0.000 abstract 1
- 230000000451 tissue damage Effects 0.000 abstract 1
- 231100000827 tissue damage Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/057935 WO2013062544A1 (en) | 2011-10-26 | 2011-10-26 | Cysteamine in the treatment of fibrotic disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN03049A true IN2014DN03049A (enExample) | 2015-05-15 |
Family
ID=48168215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3049DEN2014 IN2014DN03049A (enExample) | 2011-10-26 | 2011-10-26 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9468612B2 (enExample) |
| AU (1) | AU2011379972B2 (enExample) |
| BR (1) | BR112014009789A2 (enExample) |
| CA (1) | CA2853484C (enExample) |
| IN (1) | IN2014DN03049A (enExample) |
| MX (1) | MX2014004994A (enExample) |
| WO (1) | WO2013062544A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018525350A (ja) | 2015-07-02 | 2018-09-06 | ホライズン オルファン エルエルシー | Ado耐性システアミン類似体およびその使用 |
| IL261756B2 (en) * | 2016-03-17 | 2023-11-01 | Thiogenesis Therapeutics Inc | Preparations for the controlled release of cysteamine and systemic treatment of disorders sensitive to cysteamine |
| US10155948B2 (en) * | 2016-05-12 | 2018-12-18 | Kangwon National University University-Industry Cooperation Foundation and | Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications |
| GB201609940D0 (en) * | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| US10905660B2 (en) | 2016-06-07 | 2021-02-02 | Novabiotics Limited | Microparticles |
| WO2018148254A1 (en) * | 2017-02-07 | 2018-08-16 | Children's Hospital Medical Center | Treatment of asthma with cysteamine |
| ES3024932T3 (en) | 2017-09-20 | 2025-06-05 | Thiogenesis Therapeutics Inc | Compounds for the treatment of cysteamine sensitive disorders |
| US10828372B2 (en) | 2017-11-10 | 2020-11-10 | Wisconsin Alumni Research Foundation | Compositions and methods for the inhibition of fibrosis |
| WO2020079186A1 (en) | 2018-10-17 | 2020-04-23 | Novabiotics Limited | Dosage regime |
| US20220177918A1 (en) * | 2019-04-12 | 2022-06-09 | The Regents Of The University Of California | Methods for treating inherited eye defects |
| US12263144B2 (en) * | 2020-10-13 | 2025-04-01 | Accubit LLC—Biotechnology | Methods of treating IgA nephropathy with thiol-containing molecules |
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| FI906411A7 (fi) | 1988-06-28 | 1990-12-27 | La Jolla Cancer Res Foundation | Solujen lisääntymisen esto Decorinilla |
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| AU5587094A (en) | 1992-10-26 | 1994-05-24 | Kirin Brewery Company, Limited | Method for producing large latent transforming growth factor-beta complexes and large latency associated peptide |
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| JPH09512910A (ja) | 1994-05-04 | 1997-12-22 | マウント・サイナイ・ホスピタル・コーポレイション | TGF−βスーパーファミリーのサイトカインの変調因子およびそのアッセイ方法 |
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| CN101163502A (zh) | 2005-02-08 | 2008-04-16 | 根茨美公司 | 针对TGFβ的抗体 |
| EP3659588A1 (en) | 2006-01-27 | 2020-06-03 | The Regents of The University of California | Enterically coated cysteamine and salts thereof |
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| TWI535435B (zh) | 2007-11-30 | 2016-06-01 | 美國加利福尼亞大學董事會 | 使用半胱胺產物治療非酒精性脂肪肝炎(nash)之方法 |
-
2011
- 2011-10-26 BR BR112014009789A patent/BR112014009789A2/pt not_active IP Right Cessation
- 2011-10-26 WO PCT/US2011/057935 patent/WO2013062544A1/en not_active Ceased
- 2011-10-26 IN IN3049DEN2014 patent/IN2014DN03049A/en unknown
- 2011-10-26 MX MX2014004994A patent/MX2014004994A/es unknown
- 2011-10-26 US US14/353,273 patent/US9468612B2/en active Active
- 2011-10-26 AU AU2011379972A patent/AU2011379972B2/en not_active Expired - Fee Related
- 2011-10-26 CA CA2853484A patent/CA2853484C/en active Active
-
2016
- 2016-10-03 US US15/284,416 patent/US9925154B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011379972A1 (en) | 2014-05-15 |
| MX2014004994A (es) | 2014-08-27 |
| BR112014009789A2 (pt) | 2017-04-25 |
| US20140275279A1 (en) | 2014-09-18 |
| US9468612B2 (en) | 2016-10-18 |
| WO2013062544A1 (en) | 2013-05-02 |
| US20170165207A1 (en) | 2017-06-15 |
| CA2853484A1 (en) | 2013-05-02 |
| AU2011379972B2 (en) | 2016-05-12 |
| CA2853484C (en) | 2018-08-21 |
| US9925154B2 (en) | 2018-03-27 |
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