AU2011379972B2 - Cysteamine in the treatment of fibrotic disease - Google Patents
Cysteamine in the treatment of fibrotic disease Download PDFInfo
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- AU2011379972B2 AU2011379972B2 AU2011379972A AU2011379972A AU2011379972B2 AU 2011379972 B2 AU2011379972 B2 AU 2011379972B2 AU 2011379972 A AU2011379972 A AU 2011379972A AU 2011379972 A AU2011379972 A AU 2011379972A AU 2011379972 B2 AU2011379972 B2 AU 2011379972B2
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- cysteamine
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- fibrosis
- interstitial
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| TW202247838A (zh) | 2015-07-02 | 2022-12-16 | 美商地平線罕見醫學製藥有限責任公司 | Ado抗性半胱胺類似物及其用途 |
| JP7418958B2 (ja) | 2016-03-17 | 2024-01-22 | チオジェネシス セラピューティクス， インコーポレイテッド | システアミンの制御放出のための組成物及びシステアミン感受性障害の全身治療 |
| US10155948B2 (en) * | 2016-05-12 | 2018-12-18 | Kangwon National University University-Industry Cooperation Foundation and | Pharmaceutical composition for preventing or treating diabetic complications and screening method for preventive or therapeutic agent for diabetic complications |
| US10905660B2 (en) | 2016-06-07 | 2021-02-02 | Novabiotics Limited | Microparticles |
| GB201609940D0 (en) * | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| US20200093764A1 (en) * | 2017-02-07 | 2020-03-26 | Children's Hospital Medical Center | Treatment of asthma with cysteamine |
| EP3684418B8 (en) | 2017-09-20 | 2025-03-19 | Thiogenesis Therapeutics, Inc. | Compounds for the treatment of cysteamine sensitive disorders |
| US10828372B2 (en) | 2017-11-10 | 2020-11-10 | Wisconsin Alumni Research Foundation | Compositions and methods for the inhibition of fibrosis |
| US20220177918A1 (en) * | 2019-04-12 | 2022-06-09 | The Regents Of The University Of California | Methods for treating inherited eye defects |
| US12263144B2 (en) | 2020-10-13 | 2025-04-01 | Accubit LLC—Biotechnology | Methods of treating IgA nephropathy with thiol-containing molecules |
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| US20100111898A1 (en) * | 2006-12-04 | 2010-05-06 | Promedior, Inc | Conjoint therapy for treating fibrotic diseases |
| US20100303870A1 (en) * | 2007-11-30 | 2010-12-02 | The Regents Of The University Of California | Methods of treating non-alcoholic steatohepatitis (nash) using cysteamine products |
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| FR2549051B1 (fr) | 1983-06-22 | 1986-05-16 | Centre Nat Rech Scient | Nouveaux agents radioprotecteurs ayant une structure amino-thioalkyle et procede pour leur preparation |
| US5262319A (en) | 1985-04-19 | 1993-11-16 | Oncogene Science, Inc. | Method for obtaining bone marrow free of tumor cells using transforming growth factor β3 |
| US5654270A (en) | 1988-06-28 | 1997-08-05 | La Jolla Cancer Research Foundation | Use of fibromodulin to prevent or reduce dermal scarring |
| US5583103A (en) | 1988-06-28 | 1996-12-10 | La Jolla Cancer Research Foundation | Inhibition of transforming growth factor beta activity |
| JP2887325B2 (ja) | 1988-06-28 | 1999-04-26 | ラ ホヤ キャンサー リサーチ ファウンデーション | デコリンによる細胞増殖の抑制 |
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| US5571714A (en) | 1988-12-22 | 1996-11-05 | Celtrix Pharmaceuticals, Inc. | Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use |
| CA2065860C (en) | 1989-09-29 | 2001-03-27 | Wayne A. Border | Inhibiting transforming growth factor .beta. to prevent accumulation of extracellular matrix |
| DE69024369T2 (de) | 1989-11-22 | 1996-06-13 | Genentech, Inc., South San Francisco, Calif. | Latenz assoziierte peptide und deren verwendung |
| WO1991010727A1 (en) | 1990-01-22 | 1991-07-25 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors |
| US5554655A (en) | 1991-09-30 | 1996-09-10 | Jess G. Thoene | Method of treating HIV infection |
| US6008011A (en) | 1991-10-31 | 1999-12-28 | Whitehead Institute For Biomedical Research | TGF-β type II receptor cDNAs |
| JP4124815B2 (ja) | 1991-10-31 | 2008-07-23 | ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ | ＴＧＦ−β型受容体ｃＤＮＡおよびその用途 |
| WO1993009800A1 (en) | 1991-11-14 | 1993-05-27 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors and methods for preventing or reducing scarring |
| GB9205800D0 (en) | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
| US5869462A (en) | 1992-09-10 | 1999-02-09 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| US5821234A (en) | 1992-09-10 | 1998-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of proliferation of vascular smooth muscle cell |
| WO1994009812A1 (en) | 1992-10-26 | 1994-05-11 | Kirin Brewery Company, Limited | METHOD FOR PRODUCING LARGE LATENT TRANSFORMING GROWTH FACTOR-β COMPLEXES AND LARGE LATENCY ASSOCIATED PEPTIDE |
| JPH08504763A (ja) | 1992-10-29 | 1996-05-21 | セルトリックス ファーマシューティカルズ，インコーポレイテッド | 治療薬としてのＴＧＦ−βレセプターフラグメントの使用 |
| AU5541094A (en) | 1992-10-30 | 1994-05-24 | Consejo Superior De Investigaciones Cientificas | Compositions and methods for modifying the regulatory activity of tgf-beta |
| US5830847A (en) | 1992-10-30 | 1998-11-03 | Hsc Research & Development Limited Partnership | Soluble TGF-β-binding endoglin polypeptides and homodimers |
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| CA2853484A1 (en) | 2013-05-02 |
| BR112014009789A2 (pt) | 2017-04-25 |
| IN2014DN03049A (enExample) | 2015-05-15 |
| CA2853484C (en) | 2018-08-21 |
| US20140275279A1 (en) | 2014-09-18 |
| US9468612B2 (en) | 2016-10-18 |
| AU2011379972A1 (en) | 2014-05-15 |
| US9925154B2 (en) | 2018-03-27 |
| WO2013062544A1 (en) | 2013-05-02 |
| US20170165207A1 (en) | 2017-06-15 |
| MX2014004994A (es) | 2014-08-27 |
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