IN2014CN03614A - - Google Patents

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Publication number
IN2014CN03614A
IN2014CN03614A IN3614CHN2014A IN2014CN03614A IN 2014CN03614 A IN2014CN03614 A IN 2014CN03614A IN 3614CHN2014 A IN3614CHN2014 A IN 3614CHN2014A IN 2014CN03614 A IN2014CN03614 A IN 2014CN03614A
Authority
IN
India
Prior art keywords
magnetic field
sample
sample chamber
light
clusters
Prior art date
Application number
Other languages
English (en)
Inventor
Johannes Joseph Hubertina Barbara Schleipen
Menno Wiilem Jose Prins
Andrea Ranzoni
Original Assignee
Koninkl Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Nv filed Critical Koninkl Philips Nv
Publication of IN2014CN03614A publication Critical patent/IN2014CN03614A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0303Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/49Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1727Magnetomodulation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251Colorimeters; Construction thereof
    • G01N21/253Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
IN3614CHN2014 2011-11-14 2012-11-06 IN2014CN03614A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161559307P 2011-11-14 2011-11-14
PCT/IB2012/056186 WO2013072806A1 (en) 2011-11-14 2012-11-06 Apparatus for cluster detection

Publications (1)

Publication Number Publication Date
IN2014CN03614A true IN2014CN03614A (enExample) 2015-10-09

Family

ID=47324244

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3614CHN2014 IN2014CN03614A (enExample) 2011-11-14 2012-11-06

Country Status (7)

Country Link
US (1) US9863863B2 (enExample)
EP (1) EP2780692A1 (enExample)
JP (1) JP6225114B2 (enExample)
CN (1) CN103930765B (enExample)
BR (1) BR112014011259A2 (enExample)
IN (1) IN2014CN03614A (enExample)
WO (1) WO2013072806A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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TWI582408B (zh) 2011-08-29 2017-05-11 安美基公司 用於非破壞性檢測-流體中未溶解粒子之方法及裝置
US10156520B2 (en) 2013-06-07 2018-12-18 Malvern Panalytical Limited Array based sample characterization
CN109804235B (zh) * 2016-11-30 2022-05-13 国立研究开发法人产业技术综合研究所 目标物质检测装置及目标物质检测方法
WO2018100780A1 (ja) * 2016-11-30 2018-06-07 国立研究開発法人産業技術総合研究所 標的物質検出装置及び標的物質検出方法
JP2020509357A (ja) * 2017-02-10 2020-03-26 アムジエン・インコーポレーテツド 流体が充填された容器内の粒子を計数及びサイズ計測する撮像システム
US10088660B2 (en) 2017-02-10 2018-10-02 Amgen Inc. Imaging system for counting and sizing particles in fluid-filled vessels
CN107121649B (zh) * 2017-03-29 2023-10-10 金华职业技术学院 一种使用磁强计测量磁性分子团簇磁矩的方法
GB2566995B (en) * 2017-09-29 2023-01-18 Cotton Mouton Diagnostics Ltd A method of detection
TWI776251B (zh) * 2020-10-08 2022-09-01 中原大學 基於目標分子吸附之磁控量測系統
KR102856352B1 (ko) * 2020-10-16 2025-09-04 삼성전자주식회사 다채널 액체 파티클 계수기
CN116121051B (zh) * 2023-03-14 2023-09-01 鲲鹏(徐州)科学仪器有限公司 一种光学检测装置

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JP2807777B2 (ja) 1994-09-09 1998-10-08 工業技術院長 スラブ光導波路を利用した光吸収スペクトル測定装置
JPH10332698A (ja) * 1997-06-03 1998-12-18 Hitachi Ltd 特異的結合反応の判定方法
DE19825518C2 (de) * 1998-06-08 2001-10-04 Fresenius Ag Vorrichtung zur Messung von Parameteränderungen an lichtdurchlässigen Objekten
JP2004500572A (ja) * 2000-03-13 2004-01-08 ジェノスペクトラ,インコーポレイティド 光ファイバ走査装置
JP3695340B2 (ja) * 2001-03-30 2005-09-14 株式会社日立製作所 Dna検査方法及びその装置並びに蛍光検出方法
DE10137665A1 (de) * 2001-05-09 2002-11-14 Kilian Hennes Vorrichtung und Verfahren zum Erfassen und Klassifizieren von biologischen Partikeln oder Molekülen
JP2009058523A (ja) * 2001-05-10 2009-03-19 Yokogawa Electric Corp バイオチップ読取装置
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US7149396B2 (en) * 2003-06-16 2006-12-12 The Regents Of The University Of California Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides
JP2005070031A (ja) * 2003-08-01 2005-03-17 Shimadzu Corp マイクロチップを用いた成分分析装置
JP4401897B2 (ja) * 2004-08-19 2010-01-20 独立行政法人理化学研究所 レシオイメージング装置
US7248361B2 (en) * 2005-12-22 2007-07-24 Palo Alto Research Center Incorporated Fluorescence reader based on anti-resonant waveguide excitation
SE529474C2 (sv) * 2006-04-19 2007-08-21 Imego Ab Detekteringsanordning och förfarande
RU2460058C2 (ru) 2006-12-19 2012-08-27 Конинклейке Филипс Электроникс Н.В. Измерение параметров агглютинации
JP2010530956A (ja) * 2007-02-23 2010-09-16 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 磁性粒子を感知するセンサ装置及び方法
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Also Published As

Publication number Publication date
WO2013072806A1 (en) 2013-05-23
BR112014011259A2 (pt) 2017-04-25
CN103930765B (zh) 2017-10-13
US9863863B2 (en) 2018-01-09
US20140302619A1 (en) 2014-10-09
CN103930765A (zh) 2014-07-16
JP2014535060A (ja) 2014-12-25
EP2780692A1 (en) 2014-09-24
JP6225114B2 (ja) 2017-11-01

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