IN2013CH01199A - - Google Patents

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Publication number
IN2013CH01199A
IN2013CH01199A IN1199CH2013A IN2013CH01199A IN 2013CH01199 A IN2013CH01199 A IN 2013CH01199A IN 1199CH2013 A IN1199CH2013 A IN 1199CH2013A IN 2013CH01199 A IN2013CH01199 A IN 2013CH01199A
Authority
IN
India
Prior art keywords
formula
compounds
useful
preparation
pharmaceutically acceptable
Prior art date
Application number
Other languages
English (en)
Inventor
Ramakrishna Nirogi
Anil Karbhari Shinde
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DK13811624.9T priority Critical patent/DK2976337T3/en
Priority to BR112015024060A priority patent/BR112015024060A2/pt
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Priority to SG11201507763RA priority patent/SG11201507763RA/en
Priority to MX2015012350A priority patent/MX364929B/es
Priority to CA2907620A priority patent/CA2907620C/en
Priority to KR1020157030158A priority patent/KR101815307B1/ko
Priority to IN1199CH2013 priority patent/IN2013CH01199A/en
Priority to US14/777,925 priority patent/US9790211B2/en
Priority to PCT/IN2013/000639 priority patent/WO2014147636A1/en
Priority to EA201591844A priority patent/EA029365B1/ru
Priority to ES13811624.9T priority patent/ES2674993T3/es
Priority to JP2016504852A priority patent/JP6185650B2/ja
Priority to AU2013382944A priority patent/AU2013382944B2/en
Priority to NZ712369A priority patent/NZ712369A/en
Priority to AP2015008742A priority patent/AP2015008742A0/xx
Priority to EP13811624.9A priority patent/EP2976337B1/de
Priority to CN201380074877.9A priority patent/CN105164119B/zh
Publication of IN2013CH01199A publication Critical patent/IN2013CH01199A/en
Priority to ZA2015/06804A priority patent/ZA201506804B/en
Priority to HK16105434.5A priority patent/HK1217483A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57426Specifically defined cancers leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82Translation products from oncogenes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epidemiology (AREA)
IN1199CH2013 2013-03-20 2013-10-18 IN2013CH01199A (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
ES13811624.9T ES2674993T3 (es) 2013-03-20 2013-10-18 Derivados de 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-HT4
EA201591844A EA029365B1 (ru) 2013-03-20 2013-10-18 5-амино-хинолин-8-карбоксамидные производные в качестве агонистов 5-htрецептора
JP2016504852A JP6185650B2 (ja) 2013-03-20 2013-10-18 5−ht4受容体アゴニストとしての5−アミノ−キノリン−8−カルボキサミド誘導体
BR112015024060A BR112015024060A2 (pt) 2013-03-20 2013-10-18 composto, composição farmacêutica, método para o tratamento de doenças e uso de um composto
CA2907620A CA2907620C (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
KR1020157030158A KR101815307B1 (ko) 2013-03-20 2013-10-18 5-ht4 수용체 효능제로서 5-아미노-퀴놀린-8-카르복사미드 유도체
IN1199CH2013 IN2013CH01199A (de) 2013-03-20 2013-10-18
US14/777,925 US9790211B2 (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists
PCT/IN2013/000639 WO2014147636A1 (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
DK13811624.9T DK2976337T3 (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists
MX2015012350A MX364929B (es) 2013-03-20 2013-10-18 Derivados de la 5-amino-quinolina-8-carboxamida como agonistas del receptor 5-ht4.
SG11201507763RA SG11201507763RA (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
AU2013382944A AU2013382944B2 (en) 2013-03-20 2013-10-18 5-Amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists
NZ712369A NZ712369A (en) 2013-03-20 2013-10-18 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
AP2015008742A AP2015008742A0 (en) 2013-03-20 2013-10-18 5-amino quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
EP13811624.9A EP2976337B1 (de) 2013-03-20 2013-10-18 5-amino-chinolin-8-carboxamid- derivate als 5-ht4 rezeptor agonisten
CN201380074877.9A CN105164119B (zh) 2013-03-20 2013-10-18 作为5‑ht4受体激动剂的5‑氨基‑喹啉‑8‑甲酰胺衍生物
ZA2015/06804A ZA201506804B (en) 2013-03-20 2015-09-14 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists
HK16105434.5A HK1217483A1 (zh) 2013-03-20 2016-05-12 作爲 受體激動劑的 -氨基-喹啉- -甲酰胺衍生物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1199CH2013 IN2013CH01199A (de) 2013-03-20 2013-10-18

Publications (1)

Publication Number Publication Date
IN2013CH01199A true IN2013CH01199A (de) 2015-08-14

Family

ID=54325095

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1199CH2013 IN2013CH01199A (de) 2013-03-20 2013-10-18

Country Status (19)

Country Link
US (1) US9790211B2 (de)
EP (1) EP2976337B1 (de)
JP (1) JP6185650B2 (de)
KR (1) KR101815307B1 (de)
CN (1) CN105164119B (de)
AP (1) AP2015008742A0 (de)
AU (1) AU2013382944B2 (de)
BR (1) BR112015024060A2 (de)
CA (1) CA2907620C (de)
DK (1) DK2976337T3 (de)
EA (1) EA029365B1 (de)
ES (1) ES2674993T3 (de)
HK (1) HK1217483A1 (de)
IN (1) IN2013CH01199A (de)
MX (1) MX364929B (de)
NZ (1) NZ712369A (de)
SG (1) SG11201507763RA (de)
WO (1) WO2014147636A1 (de)
ZA (1) ZA201506804B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201909997T4 (tr) * 2015-02-13 2019-07-22 Suven Life Sciences Ltd 5-HT4 reseptör agonistleri olarak amid bileşikleri.
CN109444301A (zh) * 2018-12-18 2019-03-08 江苏省中医院 一种测定血浆中普芦卡必利浓度的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5150393A (en) * 1992-10-13 1994-05-09 Smithkline Beecham Plc Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists
AU680453B2 (en) 1992-11-05 1997-07-31 Smithkline Beecham Plc Piperidine derivatives as 5-HT4 receptor antagonists
FR2756564B1 (fr) * 1996-12-04 2004-05-14 Synthelabo Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique
WO2001095902A1 (en) * 2000-06-15 2001-12-20 Respiratorius Ab A composition comprising a combination of receptor agonists and antagonists
AU2004254193B2 (en) * 2003-06-19 2010-02-18 Janssen Pharmaceutica N.V. 5ht4-antagonistic 4-(aminomethyl)-piperidine benzamides
ES2338882T3 (es) 2003-11-24 2010-05-13 Pfizer, Inc. Compuestos de acido quinolona-carboxilico que tienen actividad agonista del receptor 5-ht4.
EP1701951B1 (de) * 2003-12-23 2010-02-10 Serodus AS Modulatoren von peripheren 5-ht-rezeptoren
WO2005092882A1 (en) * 2004-03-01 2005-10-06 Pfizer Japan, Inc. 4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders
DK1856114T3 (en) 2005-02-25 2014-11-17 Raqualia Pharma Inc Benzisoxazol-DERIVATIVES
US7906532B2 (en) 2005-07-22 2011-03-15 Pfizer Inc. Indazole derivatives
GB0525661D0 (en) * 2005-12-16 2006-01-25 Glaxo Group Ltd Novel compounds
RU2569733C2 (ru) * 2010-02-12 2015-11-27 Раквалиа Фарма Инк. Агонисты 5-нт4-рецепторов для лечения деменции
CN102762554A (zh) 2010-02-16 2012-10-31 辉瑞大药厂 5-ht4受体的部分激动剂(r)-4-((4-((4-(四氢呋喃-3-基氧基)苯并[d]异*唑-3-基氧基)甲基)哌啶-1-基)甲基)四氢-2h-吡喃-4-醇

Also Published As

Publication number Publication date
NZ712369A (en) 2016-11-25
AP2015008742A0 (en) 2015-09-30
SG11201507763RA (en) 2015-10-29
KR20160004274A (ko) 2016-01-12
BR112015024060A2 (pt) 2017-07-18
ES2674993T3 (es) 2018-07-05
JP2016516089A (ja) 2016-06-02
US9790211B2 (en) 2017-10-17
EP2976337A1 (de) 2016-01-27
KR101815307B1 (ko) 2018-01-04
ZA201506804B (en) 2016-07-27
JP6185650B2 (ja) 2017-08-23
MX364929B (es) 2019-05-14
EP2976337B1 (de) 2018-05-02
CN105164119A (zh) 2015-12-16
CA2907620A1 (en) 2014-09-25
HK1217483A1 (zh) 2017-01-13
EA201591844A1 (ru) 2016-08-31
CN105164119B (zh) 2017-12-08
AU2013382944B2 (en) 2016-08-04
AU2013382944A1 (en) 2015-10-08
US20160280694A1 (en) 2016-09-29
CA2907620C (en) 2018-03-13
MX2015012350A (es) 2016-05-09
WO2014147636A1 (en) 2014-09-25
DK2976337T3 (en) 2018-07-16
EA029365B1 (ru) 2018-03-30
WO2014147636A8 (en) 2014-12-04

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