AP2015008742A0 - 5-amino quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists - Google Patents
5-amino quinoline-8-carboxamide derivatives as 5-ht4 receptor agonistsInfo
- Publication number
- AP2015008742A0 AP2015008742A0 AP2015008742A AP2015008742A AP2015008742A0 AP 2015008742 A0 AP2015008742 A0 AP 2015008742A0 AP 2015008742 A AP2015008742 A AP 2015008742A AP 2015008742 A AP2015008742 A AP 2015008742A AP 2015008742 A0 AP2015008742 A0 AP 2015008742A0
- Authority
- AP
- ARIPO
- Prior art keywords
- receptor agonists
- carboxamide derivatives
- amino quinoline
- quinoline
- amino
- Prior art date
Links
- 108091005482 5-HT4 receptors Proteins 0.000 title 1
- RPMSTHVPCJNFMM-UHFFFAOYSA-N 5-aminoquinoline-8-carboxamide Chemical class C1=CN=C2C(C(=O)N)=CC=C(N)C2=C1 RPMSTHVPCJNFMM-UHFFFAOYSA-N 0.000 title 1
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/82—Translation products from oncogenes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2013/000639 WO2014147636A1 (en) | 2013-03-20 | 2013-10-18 | 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists |
| IN1199CH2013 IN2013CH01199A (xx) | 2013-03-20 | 2013-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2015008742A0 true AP2015008742A0 (en) | 2015-09-30 |
Family
ID=54325095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2015008742A AP2015008742A0 (en) | 2013-03-20 | 2013-10-18 | 5-amino quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US9790211B2 (xx) |
| EP (1) | EP2976337B1 (xx) |
| JP (1) | JP6185650B2 (xx) |
| KR (1) | KR101815307B1 (xx) |
| CN (1) | CN105164119B (xx) |
| AP (1) | AP2015008742A0 (xx) |
| AU (1) | AU2013382944B2 (xx) |
| BR (1) | BR112015024060A2 (xx) |
| CA (1) | CA2907620C (xx) |
| DK (1) | DK2976337T3 (xx) |
| EA (1) | EA029365B1 (xx) |
| ES (1) | ES2674993T3 (xx) |
| HK (1) | HK1217483A1 (xx) |
| IN (1) | IN2013CH01199A (xx) |
| MX (1) | MX364929B (xx) |
| NZ (1) | NZ712369A (xx) |
| SG (1) | SG11201507763RA (xx) |
| WO (1) | WO2014147636A1 (xx) |
| ZA (1) | ZA201506804B (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD3265459T2 (ro) * | 2015-02-13 | 2019-09-30 | Suven Life Sciences Ltd | Compuși amidici în calitate de agoniști ai receptorilor 5-HT4 |
| CN109444301A (zh) * | 2018-12-18 | 2019-03-08 | 江苏省中医院 | 一种测定血浆中普芦卡必利浓度的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0664805A1 (en) | 1992-10-13 | 1995-08-02 | Smithkline Beecham Plc | Heterocyclic -esters or -amides used as 5-ht 4? receptor antagonists |
| US5705498A (en) | 1992-11-05 | 1998-01-06 | Smithkline Beecham Plc. | Piperidine derivatives as 5-HT4 receptor antagonists |
| FR2756564B1 (fr) * | 1996-12-04 | 2004-05-14 | Synthelabo | Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique |
| AU2001225663A1 (en) * | 2000-06-15 | 2001-12-24 | Respiratorius Ab | A composition comprising a combination of receptor agonists and antagonists |
| KR20060022702A (ko) * | 2003-06-19 | 2006-03-10 | 얀센 파마슈티카 엔.브이. | 5ｈｔ4-길항성 4-(아미노메틸)-피페리딘벤즈아미드 |
| BRPI0416813A (pt) | 2003-11-24 | 2007-03-06 | Pfizer | compostos de ácido quinolonacarboxìlico com atividade agonista do receptor 5-ht4 |
| DE602004025508D1 (de) * | 2003-12-23 | 2010-03-25 | Serodus As | Modulatoren von peripheren 5-ht-rezeptoren |
| WO2005092882A1 (en) * | 2004-03-01 | 2005-10-06 | Pfizer Japan, Inc. | 4-amino-5-halogeno-benzamide derivatives as 5-ht4 receptor agonists for the treatment of gastrointestinal, cns, neurological and cardiovascular disorders |
| ES2523459T3 (es) | 2005-02-25 | 2014-11-26 | Raqualia Pharma Inc | Derivados de benzisoxazol |
| ATE449092T1 (de) | 2005-07-22 | 2009-12-15 | Pfizer | Indazolcarbonsäureamidderivate als agonisten des 5ht4-rezeptors |
| GB0525661D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Novel compounds |
| US8980922B2 (en) * | 2010-02-12 | 2015-03-17 | Raqualia Pharma Inc. | 5-HT4 receptor agonists for the treatment of dementia |
| EP2536713A1 (en) | 2010-02-16 | 2012-12-26 | Pfizer Inc. | (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors |
-
2013
- 2013-10-18 DK DK13811624.9T patent/DK2976337T3/en active
- 2013-10-18 MX MX2015012350A patent/MX364929B/es active IP Right Grant
- 2013-10-18 CA CA2907620A patent/CA2907620C/en not_active Expired - Fee Related
- 2013-10-18 US US14/777,925 patent/US9790211B2/en not_active Expired - Fee Related
- 2013-10-18 EA EA201591844A patent/EA029365B1/ru not_active IP Right Cessation
- 2013-10-18 CN CN201380074877.9A patent/CN105164119B/zh not_active Expired - Fee Related
- 2013-10-18 NZ NZ712369A patent/NZ712369A/en not_active IP Right Cessation
- 2013-10-18 WO PCT/IN2013/000639 patent/WO2014147636A1/en active Application Filing
- 2013-10-18 IN IN1199CH2013 patent/IN2013CH01199A/en unknown
- 2013-10-18 KR KR1020157030158A patent/KR101815307B1/ko active IP Right Grant
- 2013-10-18 BR BR112015024060A patent/BR112015024060A2/pt not_active IP Right Cessation
- 2013-10-18 EP EP13811624.9A patent/EP2976337B1/en active Active
- 2013-10-18 JP JP2016504852A patent/JP6185650B2/ja not_active Expired - Fee Related
- 2013-10-18 AU AU2013382944A patent/AU2013382944B2/en not_active Ceased
- 2013-10-18 ES ES13811624.9T patent/ES2674993T3/es active Active
- 2013-10-18 AP AP2015008742A patent/AP2015008742A0/xx unknown
- 2013-10-18 SG SG11201507763RA patent/SG11201507763RA/en unknown
-
2015
- 2015-09-14 ZA ZA2015/06804A patent/ZA201506804B/en unknown
-
2016
- 2016-05-12 HK HK16105434.5A patent/HK1217483A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2976337A1 (en) | 2016-01-27 |
| IN2013CH01199A (xx) | 2015-08-14 |
| JP6185650B2 (ja) | 2017-08-23 |
| JP2016516089A (ja) | 2016-06-02 |
| US20160280694A1 (en) | 2016-09-29 |
| US9790211B2 (en) | 2017-10-17 |
| ZA201506804B (en) | 2016-07-27 |
| SG11201507763RA (en) | 2015-10-29 |
| KR101815307B1 (ko) | 2018-01-04 |
| WO2014147636A8 (en) | 2014-12-04 |
| CN105164119B (zh) | 2017-12-08 |
| CA2907620C (en) | 2018-03-13 |
| HK1217483A1 (zh) | 2017-01-13 |
| WO2014147636A1 (en) | 2014-09-25 |
| ES2674993T3 (es) | 2018-07-05 |
| NZ712369A (en) | 2016-11-25 |
| EA201591844A1 (ru) | 2016-08-31 |
| EA029365B1 (ru) | 2018-03-30 |
| AU2013382944A1 (en) | 2015-10-08 |
| CA2907620A1 (en) | 2014-09-25 |
| BR112015024060A2 (pt) | 2017-07-18 |
| DK2976337T3 (en) | 2018-07-16 |
| KR20160004274A (ko) | 2016-01-12 |
| MX364929B (es) | 2019-05-14 |
| AU2013382944B2 (en) | 2016-08-04 |
| EP2976337B1 (en) | 2018-05-02 |
| MX2015012350A (es) | 2016-05-09 |
| CN105164119A (zh) | 2015-12-16 |
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