IN2012DN03391A - - Google Patents
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- Publication number
- IN2012DN03391A IN2012DN03391A IN3391DEN2012A IN2012DN03391A IN 2012DN03391 A IN2012DN03391 A IN 2012DN03391A IN 3391DEN2012 A IN3391DEN2012 A IN 3391DEN2012A IN 2012DN03391 A IN2012DN03391 A IN 2012DN03391A
- Authority
- IN
- India
- Prior art keywords
- compound
- methyl
- processes
- relates
- luoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26226309P | 2009-11-18 | 2009-11-18 | |
| PCT/SE2010/051269 WO2011062550A1 (en) | 2009-11-18 | 2010-11-17 | Benzoimidazole compounds and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN03391A true IN2012DN03391A (ru) | 2015-10-23 |
Family
ID=44059844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN3391DEN2012 IN2012DN03391A (ru) | 2009-11-18 | 2010-11-17 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8530467B2 (ru) |
| EP (1) | EP2501697B1 (ru) |
| JP (1) | JP5657018B2 (ru) |
| KR (1) | KR20120113709A (ru) |
| CN (1) | CN102741245B (ru) |
| AR (1) | AR079050A1 (ru) |
| AU (1) | AU2010322478B2 (ru) |
| BR (1) | BR112012011518B8 (ru) |
| CA (1) | CA2777746C (ru) |
| ES (1) | ES2442797T3 (ru) |
| IN (1) | IN2012DN03391A (ru) |
| MX (1) | MX2012005329A (ru) |
| RU (1) | RU2542582C2 (ru) |
| TW (1) | TW201121957A (ru) |
| UY (1) | UY33037A (ru) |
| WO (1) | WO2011062550A1 (ru) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012158117A1 (en) * | 2011-05-17 | 2012-11-22 | Astrazeneca Ab | Combination therapies for treating pain |
| CA2898665C (en) * | 2013-01-31 | 2021-02-16 | Neomed Institute | Imidazopyridine compounds and their use as p2x purinoreceptor modulators |
| CN105992761A (zh) * | 2013-12-20 | 2016-10-05 | 盐野义制药株式会社 | 具有血小板生成素受体激动作用的光学活性的化合物及其中间体的制备方法 |
| EP3981406A1 (en) * | 2014-07-03 | 2022-04-13 | Afferent Pharmaceuticals Inc. | Methods and compositions for treating diseases and conditions |
| US10111883B1 (en) * | 2017-09-18 | 2018-10-30 | Bellus Health Cough Inc. | Selective P2X3 modulators |
| CN108904507A (zh) * | 2018-02-11 | 2018-11-30 | 赖英杰 | P2x3受体调节剂苯并咪唑化合物在制备抗呼吸疾病药物中的应用 |
| SG11202106706TA (en) * | 2018-12-29 | 2021-07-29 | Wuhan Ll Science And Technology Development Co Ltd | Heterocyclic compound intermediate, preparation method therefor and application thereof |
| EP4198034A4 (en) * | 2020-08-13 | 2024-01-17 | Tuojie Biotech Shanghai Co Ltd | BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR MEDICAL USE |
| WO2022117062A1 (zh) * | 2020-12-04 | 2022-06-09 | 上海拓界生物医药科技有限公司 | 含有稠合三环的化合物及其医药用途 |
| CN114478508A (zh) * | 2021-12-31 | 2022-05-13 | 淮北师范大学 | 一种苯并咪唑化合物的结晶形式 |
| WO2023151658A1 (zh) * | 2022-02-11 | 2023-08-17 | 江苏恒瑞医药股份有限公司 | 一种p2x3受体拮抗剂的可药用盐及其制备方法 |
| TW202342468A (zh) * | 2022-02-11 | 2023-11-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | P2x3受體拮抗劑的晶型及其製備方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6026A (en) * | 1849-01-09 | Cast-iron car-wheel | ||
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| IL125686A (en) | 1996-02-13 | 2002-11-10 | Zeneca Ltd | Quinazoline derivatives, processes for their preparation, pharmaceutical preparations containing them and their use in the manufacture of a drug with an anti-angiogenic effect and / or an effect of reducing vascular permeability |
| DE69709319T2 (de) | 1996-03-05 | 2002-08-14 | Astrazeneca Ab | 4-anilinochinazolin derivate |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| KR20080015482A (ko) | 1999-02-10 | 2008-02-19 | 아스트라제네카 아베 | 혈관형성 억제제로서의 퀴나졸린 유도체 |
| EP1249450B1 (en) * | 2000-01-17 | 2007-10-10 | Teijin Pharma Limited | Benzimidazole derivatives as human chymase inhibitors |
| CN1431999A (zh) | 2000-05-31 | 2003-07-23 | 阿斯特拉曾尼卡有限公司 | 具有血管损伤活性的吲哚衍生物 |
| UA73993C2 (ru) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хиназолиновые производные для лечения опухолей и фармацевтическая композиция |
| MXPA02012903A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como inhibidores de angiogenesis. |
| CN1255391C (zh) | 2000-07-07 | 2006-05-10 | 安吉奥金尼药品有限公司 | 作为血管破坏剂的colchinol衍生物 |
| BRPI0515897A (pt) * | 2004-09-24 | 2008-08-12 | Astrazeneca Ab | composto, uso do mesmo, composição farmacêutica, e, método para a terapia de dor em um animal de sangue quente, e para a preparação de um composto |
| CN101674827A (zh) * | 2007-03-02 | 2010-03-17 | 先灵公司 | 苯并咪唑衍生物及其使用方法 |
| US20090099195A1 (en) | 2007-05-08 | 2009-04-16 | Astrazeneca Ab | Therapeutic Compounds 570 |
| CA2703909A1 (en) * | 2007-10-31 | 2009-05-07 | Merck Sharp & Dohme Corp. | P2x3, receptor antagonists for treatment of pain |
-
2010
- 2010-11-17 WO PCT/SE2010/051269 patent/WO2011062550A1/en active Application Filing
- 2010-11-17 CN CN201080061596.6A patent/CN102741245B/zh active Active
- 2010-11-17 AU AU2010322478A patent/AU2010322478B2/en active Active
- 2010-11-17 CA CA2777746A patent/CA2777746C/en active Active
- 2010-11-17 EP EP10831876.7A patent/EP2501697B1/en active Active
- 2010-11-17 BR BR112012011518A patent/BR112012011518B8/pt active IP Right Grant
- 2010-11-17 ES ES10831876.7T patent/ES2442797T3/es active Active
- 2010-11-17 AR ARP100104240A patent/AR079050A1/es unknown
- 2010-11-17 MX MX2012005329A patent/MX2012005329A/es active IP Right Grant
- 2010-11-17 IN IN3391DEN2012 patent/IN2012DN03391A/en unknown
- 2010-11-17 KR KR1020127012726A patent/KR20120113709A/ko not_active Application Discontinuation
- 2010-11-17 JP JP2012539853A patent/JP5657018B2/ja active Active
- 2010-11-17 TW TW099139607A patent/TW201121957A/zh unknown
- 2010-11-17 RU RU2012124268/04A patent/RU2542582C2/ru active
- 2010-11-18 UY UY0001033037A patent/UY33037A/es not_active Application Discontinuation
-
2012
- 2012-05-16 US US13/472,825 patent/US8530467B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013511517A (ja) | 2013-04-04 |
| CA2777746C (en) | 2019-05-14 |
| JP5657018B2 (ja) | 2015-01-21 |
| BR112012011518A2 (pt) | 2016-06-28 |
| US20120289504A1 (en) | 2012-11-15 |
| TW201121957A (en) | 2011-07-01 |
| CA2777746A1 (en) | 2011-05-26 |
| KR20120113709A (ko) | 2012-10-15 |
| RU2542582C2 (ru) | 2015-02-20 |
| EP2501697A4 (en) | 2013-04-24 |
| BR112012011518B1 (pt) | 2020-03-10 |
| AR079050A1 (es) | 2011-12-21 |
| UY33037A (es) | 2011-06-30 |
| CN102741245A (zh) | 2012-10-17 |
| WO2011062550A1 (en) | 2011-05-26 |
| EP2501697B1 (en) | 2013-10-23 |
| RU2012124268A (ru) | 2013-12-27 |
| MX2012005329A (es) | 2012-05-29 |
| EP2501697A1 (en) | 2012-09-26 |
| AU2010322478A1 (en) | 2012-05-31 |
| BR112012011518B8 (pt) | 2023-01-10 |
| ES2442797T3 (es) | 2014-02-13 |
| US8530467B2 (en) | 2013-09-10 |
| CN102741245B (zh) | 2014-11-05 |
| AU2010322478B2 (en) | 2013-11-14 |
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