IN2012DN02968A - - Google Patents
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- Publication number
- IN2012DN02968A IN2012DN02968A IN2968DEN2012A IN2012DN02968A IN 2012DN02968 A IN2012DN02968 A IN 2012DN02968A IN 2968DEN2012 A IN2968DEN2012 A IN 2968DEN2012A IN 2012DN02968 A IN2012DN02968 A IN 2012DN02968A
- Authority
- IN
- India
- Prior art keywords
- present
- relates
- heterocyclic
- schizophrenia
- solvate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25110109P | 2009-10-13 | 2009-10-13 | |
| EP09172872 | 2009-10-13 | ||
| PCT/EP2010/065160 WO2011045258A1 (en) | 2009-10-13 | 2010-10-11 | Condensed azine - derivatives for the treatment of diseases related to the acetylcholine receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02968A true IN2012DN02968A (de) | 2015-07-31 |
Family
ID=42040651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2968DEN2012 IN2012DN02968A (de) | 2009-10-13 | 2010-10-11 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8841289B2 (de) |
| EP (1) | EP2488520B1 (de) |
| JP (1) | JP2013507417A (de) |
| KR (1) | KR20120100913A (de) |
| CN (1) | CN102666540A (de) |
| AU (1) | AU2010305825A1 (de) |
| BR (1) | BR112012008518A2 (de) |
| CA (1) | CA2776835A1 (de) |
| IN (1) | IN2012DN02968A (de) |
| MX (1) | MX2012004289A (de) |
| RU (1) | RU2012119488A (de) |
| WO (1) | WO2011045258A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX336268B (es) | 2011-07-29 | 2016-01-13 | Toyama Chemical Co Ltd | Compuesto de amidina o sal del mismo. |
| ES2611504T3 (es) | 2012-03-07 | 2017-05-09 | Institute Of Cancer Research: Royal Cancer Hospital (The) | Compuestos de isoquinolin-1-ona 3-aril-5-sustituida y sus usos terapéuticos |
| AU2013264943B2 (en) * | 2012-05-22 | 2018-02-01 | King Abdullah University Of Science And Technology | Combination comprising parthenolide for use in the treatment of Alzheimer's Disease and other neurodegenerative disorders |
| DK3044221T3 (en) | 2013-09-11 | 2018-04-23 | Institute Of Cancer Res Royal Cancer Hospital The | 3-ARYL-5-SUBSTITUTED-ISOQUINOLIN-1-ON COMPOUNDS AND THERAPEUTIC APPLICATION THEREOF |
| EP3191459A1 (de) | 2014-09-05 | 2017-07-19 | AbbVie Deutschland GmbH & Co. KG | Kondensierte heterocyclischen oder carbocyclischen verbindungen mit substituierten cycloaliphatischen rest und verwendung zur behandlung von vasopressin-erkrankungen |
| CA2971413A1 (en) | 2014-12-16 | 2016-06-23 | Axovant Sciences Gmbh | Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors |
| TWI698436B (zh) | 2014-12-30 | 2020-07-11 | 美商佛瑪治療公司 | 作為泛素特異性蛋白酶７抑制劑之吡咯并及吡唑并嘧啶 |
| MA41291A (fr) | 2014-12-30 | 2017-11-07 | Forma Therapeutics Inc | Dérivés de la pyrrolotriazinone et de l'imidazotriazinone en tant qu'inhibiteurs de la protéase spécifique de l'ubiquitine n° 7 (usp7) pour le traitement d'un cancer |
| EP3253759A1 (de) | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Isothiazolpyrimidinone, pyrazolopyrimidinone und pyrrolopyrimidinone als ubiquitin-spezifische protease-7-hemmer |
| WO2016126926A1 (en) | 2015-02-05 | 2016-08-11 | Forma Therapeutics, Inc. | Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors |
| EP3253765A1 (de) | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Thienopyrimidinone als ubiquitin-spezifische protease 7-inhibitoren |
| CN106146410B (zh) * | 2015-04-03 | 2018-10-12 | 中南大学 | 6-氨基-4(3h)-喹唑啉酮衍生物及其合成方法和用途 |
| CN106279211B (zh) * | 2015-06-03 | 2020-09-15 | 北京大学 | 一种噻唑并嘧啶酮化合物及其制备方法和应用 |
| MX2017016231A (es) | 2015-06-10 | 2018-11-29 | Axovant Sciences Gmbh | Compuestos de aminobencisoxazol como agonistas de receptores a7-nicotínicos de acetilcolina. |
| JP2018523707A (ja) | 2015-08-12 | 2018-08-23 | アクソバント サイエンシズ ゲーエムベーハー | α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換アミノベンゾイソオキサゾール化合物 |
| EP3386990B1 (de) | 2015-12-09 | 2023-04-19 | Novartis AG | Thienopyrimidinon-nmda-rezeptor-modulatoren und verwendungen davon |
| DK3386591T3 (da) * | 2015-12-09 | 2020-09-28 | Cadent Therapeutics Inc | Heteroaromatic nmda receptor modulators and uses thereof |
| AU2017382339B2 (en) | 2016-12-22 | 2024-02-15 | Novartis Ag | NMDA receptor modulators and uses thereof |
| US20220287748A1 (en) * | 2018-06-27 | 2022-09-15 | Reborna Biosciences, Inc. | Prophylactic or therapeutic agent for spinal muscular atrophy |
| HU231414B1 (hu) * | 2018-07-13 | 2023-08-28 | Richter Gedeon Nyrt. | Tiadiazin származékok |
| US20220089609A1 (en) | 2018-07-26 | 2022-03-24 | Domain Therapeutics | Substituted quinazolinone derivatives and their use as positive allosteric modulators of mglur4 |
| PE20210948A1 (es) | 2018-08-03 | 2021-05-24 | Cadent Therapeutics Inc | Moduladores del receptor nmda heteroaromatico y usos de los mismos |
| EP4126847A1 (de) | 2020-03-30 | 2023-02-08 | ENYO Pharma | Chinazolinonderivate und verwendungen davon zur behandlung von krebs |
| WO2021198191A1 (en) | 2020-03-30 | 2021-10-07 | Enyo Pharma | Quinazolinone derivatives and uses thereof for treating a cancer |
| CN112898290B (zh) * | 2021-01-29 | 2022-08-05 | 中南大学 | 异噁唑甲酰胺基-4(3h)-喹唑啉酮衍生物及其合成方法和用途 |
| US11957759B1 (en) | 2022-09-07 | 2024-04-16 | Arvinas Operations, Inc. | Rapidly accelerated fibrosarcoma (RAF) degrading compounds and associated methods of use |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0000540D0 (sv) | 2000-02-18 | 2000-02-18 | Astrazeneca Ab | New compounds |
| MXPA03009650A (es) * | 2001-04-20 | 2005-03-07 | Vertex Pharma | Derivados de 9-deazoguanidina como inhibidores de gsk-3. |
| US7148236B2 (en) * | 2002-01-17 | 2006-12-12 | Merck & Co., Inc. | Modulators of acetylcholine receptors |
| GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| TW200536830A (en) * | 2004-02-06 | 2005-11-16 | Chugai Pharmaceutical Co Ltd | 1-(2H)-isoquinolone derivative |
| CN101228149B (zh) * | 2005-07-26 | 2013-01-02 | 塞诺菲-安万特股份有限公司 | 作为Rho-激酶抑制剂的哌啶基取代的异喹啉酮衍生物 |
| JP5256202B2 (ja) * | 2006-09-11 | 2013-08-07 | エム・エス・ディー・オス・ベー・フェー | キナゾリノンおよびイソキノリノンアセトアミド誘導体 |
| DK2132194T3 (da) * | 2006-12-27 | 2011-06-27 | Sanofi Aventis | Substituerede isoquinoliner og deres anvendelse som Rho-kinase inhibitorer |
| JP2010229035A (ja) * | 2007-08-01 | 2010-10-14 | Taisho Pharmaceutical Co Ltd | ピリドピリミジン−４−オン誘導体 |
| US8343960B2 (en) * | 2007-11-14 | 2013-01-01 | Neurosearch A/S | 1,4-diaza-bicyclo[3.2.2]nonyl pyrimidine derivatives and their medical use |
| US20100327809A1 (en) | 2008-02-29 | 2010-12-30 | Techno Core International Co., Ltd. | Charging apparatus and quality judging apparatus for packed battery |
-
2010
- 2010-10-11 IN IN2968DEN2012 patent/IN2012DN02968A/en unknown
- 2010-10-11 KR KR1020127009340A patent/KR20120100913A/ko not_active Application Discontinuation
- 2010-10-11 WO PCT/EP2010/065160 patent/WO2011045258A1/en active Application Filing
- 2010-10-11 MX MX2012004289A patent/MX2012004289A/es not_active Application Discontinuation
- 2010-10-11 RU RU2012119488/04A patent/RU2012119488A/ru unknown
- 2010-10-11 JP JP2012533593A patent/JP2013507417A/ja active Pending
- 2010-10-11 AU AU2010305825A patent/AU2010305825A1/en not_active Abandoned
- 2010-10-11 BR BR112012008518A patent/BR112012008518A2/pt not_active Application Discontinuation
- 2010-10-11 EP EP10771062.6A patent/EP2488520B1/de active Active
- 2010-10-11 CA CA2776835A patent/CA2776835A1/en not_active Abandoned
- 2010-10-11 CN CN2010800465507A patent/CN102666540A/zh active Pending
- 2010-10-11 US US13/501,587 patent/US8841289B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2012004289A (es) | 2012-06-12 |
| CN102666540A (zh) | 2012-09-12 |
| KR20120100913A (ko) | 2012-09-12 |
| BR112012008518A2 (pt) | 2016-04-05 |
| WO2011045258A1 (en) | 2011-04-21 |
| US8841289B2 (en) | 2014-09-23 |
| EP2488520A1 (de) | 2012-08-22 |
| CA2776835A1 (en) | 2011-04-21 |
| AU2010305825A1 (en) | 2012-04-19 |
| US20120208796A1 (en) | 2012-08-16 |
| RU2012119488A (ru) | 2013-11-20 |
| EP2488520B1 (de) | 2015-09-02 |
| JP2013507417A (ja) | 2013-03-04 |
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