IN2012DN01342A - - Google Patents
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- Publication number
- IN2012DN01342A IN2012DN01342A IN1342DEN2012A IN2012DN01342A IN 2012DN01342 A IN2012DN01342 A IN 2012DN01342A IN 1342DEN2012 A IN1342DEN2012 A IN 1342DEN2012A IN 2012DN01342 A IN2012DN01342 A IN 2012DN01342A
- Authority
- IN
- India
- Prior art keywords
- pyrimidines
- meanings
- iii
- formula
- making
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09167934 | 2009-08-14 | ||
PCT/EP2010/061840 WO2011018518A1 (en) | 2009-08-14 | 2010-08-13 | Regioselective preparation of 2 -amino-5-trifluoromethylpyrimidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN01342A true IN2012DN01342A (en, 2012) | 2015-06-05 |
Family
ID=42712695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1342DEN2012 IN2012DN01342A (en, 2012) | 2009-08-14 | 2010-08-13 |
Country Status (17)
Country | Link |
---|---|
US (1) | US8933227B2 (en, 2012) |
EP (1) | EP2464634B1 (en, 2012) |
JP (1) | JP5539519B2 (en, 2012) |
KR (1) | KR20120046248A (en, 2012) |
CN (1) | CN102471287A (en, 2012) |
AR (1) | AR077925A1 (en, 2012) |
AU (1) | AU2010283713A1 (en, 2012) |
BR (1) | BR112012002971A2 (en, 2012) |
CA (1) | CA2767965A1 (en, 2012) |
CL (1) | CL2012000278A1 (en, 2012) |
EA (1) | EA201200282A1 (en, 2012) |
IL (1) | IL217112A0 (en, 2012) |
IN (1) | IN2012DN01342A (en, 2012) |
MX (1) | MX2012001469A (en, 2012) |
NZ (1) | NZ597538A (en, 2012) |
TW (1) | TW201124385A (en, 2012) |
WO (1) | WO2011018518A1 (en, 2012) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8372974B2 (en) * | 2008-03-20 | 2013-02-12 | Boehringer Ingelheim International Gmbh | Regioselective preparation of substituted pyrimidines |
UY31714A (es) * | 2008-03-20 | 2009-11-10 | Boehringer Ingelheim Int | Preparación selectiva de pirimidinas sustituidas |
US8933227B2 (en) | 2009-08-14 | 2015-01-13 | Boehringer Ingelheim International Gmbh | Selective synthesis of functionalized pyrimidines |
WO2011018517A1 (en) | 2009-08-14 | 2011-02-17 | Boehringer Ingelheim International Gmbh | Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives |
CN102887860B (zh) * | 2012-09-29 | 2015-07-01 | 上海泰坦科技有限公司 | 4-氯-6-三氟甲基嘧啶类化合物的制备方法 |
JP6391985B2 (ja) * | 2014-05-16 | 2018-09-19 | 東ソー・ファインケム株式会社 | 2−置換−4−(2,2,2−トリフルオロエトキシ)−5−(トリフルオロメチル)ピリミジン誘導体及びその製造方法 |
JP6391988B2 (ja) * | 2014-05-21 | 2018-09-19 | 東ソー・ファインケム株式会社 | 5−(トリフルオロメチル)ピリミジン誘導体の製造方法及び新規5−(トリフルオロメチル)ピリミジン誘導体 |
JP6262079B2 (ja) * | 2014-06-02 | 2018-01-17 | 東ソー・ファインケム株式会社 | 4−(2,2,2−トリフルオロエトキシ)−5−(トリフルオロメチル)ピリミジン誘導体及びその製造方法 |
JP6431294B2 (ja) * | 2014-06-16 | 2018-11-28 | 東ソー・ファインケム株式会社 | 5−(トリフルオロメチル)ピリミジン誘導体及びその製造法 |
JP6479486B2 (ja) * | 2015-01-16 | 2019-03-06 | 東ソー・ファインケム株式会社 | 4−アルコキシ−5−(トリフルオロメチル)ピリミジン誘導体及びその製造方法 |
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DE10161763A1 (de) | 2001-12-15 | 2003-07-17 | Bayer Cropsience Ltd | Neues herbizides Verfahren |
GB0206215D0 (en) | 2002-03-15 | 2002-05-01 | Novartis Ag | Organic compounds |
AU2003231231A1 (en) | 2002-05-06 | 2003-11-11 | Bayer Pharmaceuticals Corporation | Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders |
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JP2006508997A (ja) | 2002-11-28 | 2006-03-16 | シエーリング アクチエンゲゼルシャフト | Chk−、Pdk−およびAkt−阻害性ピリミジン、それらの製造および薬剤としての使用 |
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EP1598343A1 (de) | 2004-05-19 | 2005-11-23 | Boehringer Ingelheim International GmbH | 2-Arylaminopyrimidine als PLK Inhibitoren |
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EP1705177A1 (en) | 2005-03-23 | 2006-09-27 | Schering Aktiengesellschaft | N-aryl-sulfoximine-substituted pyrimidines as CDK- and/or VEGF inhibitors, their production and use as pharmaceutical agents |
CN101218229A (zh) | 2005-05-05 | 2008-07-09 | 阿斯利康(瑞典)有限公司 | 吡唑基-氨基取代的嘧啶及其在癌症治疗中的应用 |
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US8623887B2 (en) | 2006-05-15 | 2014-01-07 | Boehringer Ingelheim International Gmbh | Compounds |
EP2027083B1 (en) | 2006-05-18 | 2012-07-11 | Boehringer Ingelheim International GmbH | Method of preparing chiral cyclic beta-aminocarboxamides |
DE102006027156A1 (de) | 2006-06-08 | 2007-12-13 | Bayer Schering Pharma Ag | Sulfimide als Proteinkinaseinhibitoren |
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UY31714A (es) | 2008-03-20 | 2009-11-10 | Boehringer Ingelheim Int | Preparación selectiva de pirimidinas sustituidas |
EA201100078A1 (ru) | 2008-06-25 | 2011-08-30 | Айрм Ллк | Производные пиримидина в качестве ингибиторов киназы |
PE20100087A1 (es) | 2008-06-25 | 2010-02-08 | Irm Llc | Compuestos y composiciones como inhibidores de cinasa |
NZ603525A (en) | 2008-06-27 | 2015-02-27 | Celgene Avilomics Res Inc | Pyrimidine based compound and uses thereof |
EP2179991A1 (de) | 2008-10-21 | 2010-04-28 | Bayer Schering Pharma Aktiengesellschaft | Sulfoximinsubstituierte Anilino-Pyrimidinderivate als CDK-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel |
EP2179992A1 (de) | 2008-10-21 | 2010-04-28 | Bayer Schering Pharma Aktiengesellschaft | Sulfonsubstituierte Anlinopyrimidinderivative als CDK-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel |
UY32240A (es) | 2008-11-14 | 2010-06-30 | Boeringer Ingelheim Kg | Nuevas 2,4-diaminopirimidinas, sus sales farmacéuticamente aceptables, composiciones conteniéndolas y aplicaciones. |
TWI491605B (zh) | 2008-11-24 | 2015-07-11 | Boehringer Ingelheim Int | 新穎化合物 |
TW201024281A (en) | 2008-11-24 | 2010-07-01 | Boehringer Ingelheim Int | New compounds |
US8933227B2 (en) | 2009-08-14 | 2015-01-13 | Boehringer Ingelheim International Gmbh | Selective synthesis of functionalized pyrimidines |
WO2011018517A1 (en) | 2009-08-14 | 2011-02-17 | Boehringer Ingelheim International Gmbh | Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives |
-
2010
- 2010-08-10 US US12/853,732 patent/US8933227B2/en active Active
- 2010-08-13 EA EA201200282A patent/EA201200282A1/ru unknown
- 2010-08-13 AU AU2010283713A patent/AU2010283713A1/en not_active Abandoned
- 2010-08-13 AR ARP100103001A patent/AR077925A1/es unknown
- 2010-08-13 EP EP10744917.5A patent/EP2464634B1/en active Active
- 2010-08-13 JP JP2012524242A patent/JP5539519B2/ja active Active
- 2010-08-13 KR KR1020127003436A patent/KR20120046248A/ko not_active Withdrawn
- 2010-08-13 IN IN1342DEN2012 patent/IN2012DN01342A/en unknown
- 2010-08-13 BR BR112012002971A patent/BR112012002971A2/pt not_active IP Right Cessation
- 2010-08-13 TW TW099127176A patent/TW201124385A/zh unknown
- 2010-08-13 CN CN2010800346368A patent/CN102471287A/zh active Pending
- 2010-08-13 NZ NZ597538A patent/NZ597538A/en not_active IP Right Cessation
- 2010-08-13 MX MX2012001469A patent/MX2012001469A/es not_active Application Discontinuation
- 2010-08-13 CA CA2767965A patent/CA2767965A1/en not_active Abandoned
- 2010-08-13 WO PCT/EP2010/061840 patent/WO2011018518A1/en active Application Filing
-
2011
- 2011-12-21 IL IL217112A patent/IL217112A0/en unknown
-
2012
- 2012-02-02 CL CL2012000278A patent/CL2012000278A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2013501759A (ja) | 2013-01-17 |
MX2012001469A (es) | 2012-02-22 |
AR077925A1 (es) | 2011-10-05 |
JP5539519B2 (ja) | 2014-07-02 |
EA201200282A1 (ru) | 2012-09-28 |
NZ597538A (en) | 2014-05-30 |
AU2010283713A1 (en) | 2012-02-02 |
BR112012002971A2 (pt) | 2015-10-13 |
CA2767965A1 (en) | 2011-02-17 |
EP2464634A1 (en) | 2012-06-20 |
CL2012000278A1 (es) | 2012-10-12 |
KR20120046248A (ko) | 2012-05-09 |
WO2011018518A1 (en) | 2011-02-17 |
IL217112A0 (en) | 2012-02-29 |
CN102471287A (zh) | 2012-05-23 |
US8933227B2 (en) | 2015-01-13 |
EP2464634B1 (en) | 2016-11-30 |
US20110190499A1 (en) | 2011-08-04 |
TW201124385A (en) | 2011-07-16 |
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