WO2012063115A3 - Process for the preparation of rosuvastatin calcium via novel amine intermediate - Google Patents
Process for the preparation of rosuvastatin calcium via novel amine intermediate Download PDFInfo
- Publication number
- WO2012063115A3 WO2012063115A3 PCT/IB2011/002633 IB2011002633W WO2012063115A3 WO 2012063115 A3 WO2012063115 A3 WO 2012063115A3 IB 2011002633 W IB2011002633 W IB 2011002633W WO 2012063115 A3 WO2012063115 A3 WO 2012063115A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- novel amine
- rosuvastatin calcium
- amine intermediate
- via novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
Abstract
The present invention, relates to novel amine salts of rosuvastatin and its process for the preparation. Moreover, the present invention also relates to improved process for the preparation of rosuvastatin calcium, employing novel amine salts as an intermediate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2702DE2010 | 2010-11-11 | ||
IN2702/DEL/2010 | 2010-11-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012063115A2 WO2012063115A2 (en) | 2012-05-18 |
WO2012063115A3 true WO2012063115A3 (en) | 2012-10-26 |
Family
ID=45444648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2011/002633 WO2012063115A2 (en) | 2010-11-11 | 2011-11-09 | Process for the preparation of rosuvastatin calcium via novel amine intermediate |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2012063115A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102967683B (en) * | 2012-11-16 | 2014-10-08 | 峨眉山天梁星制药有限公司 | High-performance liquid chromatography method for methyl(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphos phoranylidenehexanoate |
MX361000B (en) * | 2013-03-29 | 2018-11-23 | Dsm Sinochem Pharm Nl Bv | Amine salts of pitavastatin and rosuvastatin. |
MX2015013696A (en) * | 2013-03-29 | 2016-02-26 | Dsm Sinochem Pharm Nl Bv | Amine salts of pitavastatin and rosuvastatin. |
JP6114475B2 (en) | 2013-07-16 | 2017-04-12 | スヴェン・ライフ・サイエンシズ・リミテッド | Method for producing rosuvastatin calcium and method for producing novel intermediate thereof |
JP6596339B2 (en) * | 2014-02-06 | 2019-10-23 | 株式会社エーピーアイ コーポレーション | Method for producing rosuvastatin calcium and intermediates thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005077916A1 (en) * | 2004-01-19 | 2005-08-25 | Ranbaxy Laboratories Limited | Salts of hmg-coa reductase inhibitors and use thereof |
WO2008038132A1 (en) * | 2006-09-28 | 2008-04-03 | Aurobindo Pharma Limited | Crystalline diamine salts of rosuvastatin |
WO2010035284A2 (en) * | 2008-09-26 | 2010-04-01 | Matrix Laboratories Ltd | An improved process for the preparation of rosuvastatin calcium |
WO2010081861A1 (en) * | 2009-01-14 | 2010-07-22 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of rosuvastatin |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2648897B2 (en) | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | Pyrimidine derivatives |
SI20070A (en) | 1998-09-18 | 2000-04-30 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | NOVEL SALTS OF INHIBITORS OF HMG-CoA REDUCTASE |
GB0003305D0 (en) | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
EP1601658A1 (en) | 2003-11-24 | 2005-12-07 | Teva Pharmaceutical Industries Limited | Crystalline ammonium salts of rosuvastatin |
US20100069635A1 (en) | 2006-11-29 | 2010-03-18 | Dr. Reddy's Laboratories Ltd. | Rosuvastatin dehydroabietylamine salt |
-
2011
- 2011-11-09 WO PCT/IB2011/002633 patent/WO2012063115A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005077916A1 (en) * | 2004-01-19 | 2005-08-25 | Ranbaxy Laboratories Limited | Salts of hmg-coa reductase inhibitors and use thereof |
WO2008038132A1 (en) * | 2006-09-28 | 2008-04-03 | Aurobindo Pharma Limited | Crystalline diamine salts of rosuvastatin |
WO2010035284A2 (en) * | 2008-09-26 | 2010-04-01 | Matrix Laboratories Ltd | An improved process for the preparation of rosuvastatin calcium |
WO2010081861A1 (en) * | 2009-01-14 | 2010-07-22 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of rosuvastatin |
Also Published As
Publication number | Publication date |
---|---|
WO2012063115A2 (en) | 2012-05-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2014014835A3 (en) | Criystalline forms of the prolyl hydroxylase inhibitor [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid | |
WO2012025944A3 (en) | Sitagliptin, salts and polymorphs thereof | |
CA2830549C (en) | Methods and compositions for preparing noribogaine from voacangine | |
TN2011000673A1 (en) | Bace inhibitors | |
EP3778606A3 (en) | Condensed imidazolylimidazoles as antiviral compounds | |
WO2013098833A3 (en) | Processes and intermediates for preparing rivaroxaban | |
MX341456B (en) | Amino-quinolines as kinase inhibitors. | |
EP2566477A4 (en) | Amino-quinolines as kinase inhibitors | |
WO2010070658A3 (en) | Improved process for the preparation of endothelin receptor antagonists | |
WO2013121436A3 (en) | A process for preparation of rivaroxaban and intermediates thereof | |
MX2012008141A (en) | Compounds and methods. | |
WO2010102778A3 (en) | Substituted 3-aminoisoxazolopyridines as kcnq2/3 modulators | |
WO2010140765A2 (en) | Novel method for preparing rosuvastatin, intermediate compounds useful for preparing same, and method for preparing same | |
WO2012015999A3 (en) | Process for the preparation of imatinib mesylate | |
MY160677A (en) | Fermented infant formula | |
WO2008053334A3 (en) | An improved process for preparing rosuvastatin calcium | |
WO2012075117A3 (en) | Small molecule-polymer conjugates and methods of making same | |
WO2012017321A3 (en) | Treatment for dyslipidemia | |
WO2012063115A3 (en) | Process for the preparation of rosuvastatin calcium via novel amine intermediate | |
WO2010035284A3 (en) | An improved process for the preparation of rosuvastatin calcium | |
WO2010098583A2 (en) | Novel method for preparing statin compounds or salts thereof, and intermediate compounds used in same | |
MX351610B (en) | ACID ADDITION SALTS OF 5a-HYDROXY-6ß-[2-(1H-IMIDAZOL-4-YL)ETHYL AMINO]CHOLESTAN-3ß-OL. | |
WO2012140490A3 (en) | Processes for preparing pitavastatin calcium | |
EA201290243A1 (en) | Quinazoline compounds | |
WO2009062659A3 (en) | Polymorphs of enantiopure erdosteine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 11804778 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 11804778 Country of ref document: EP Kind code of ref document: A2 |