IN2012DN00338A - - Google Patents
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- Publication number
- IN2012DN00338A IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
- Authority
- IN
- India
- Prior art keywords
- methods
- relates
- present
- region containing
- containing protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27370909P | 2009-08-07 | 2009-08-07 | |
PCT/US2010/044539 WO2011017514A1 (en) | 2009-08-07 | 2010-08-05 | Methods for purifying a target protein from one or more impurities in a sample |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00338A true IN2012DN00338A (sr) | 2015-05-22 |
Family
ID=43544660
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN338DEN2012 IN2012DN00338A (sr) | 2009-08-07 | 2010-08-05 |
Country Status (9)
Country | Link |
---|---|
US (1) | US8536316B2 (sr) |
EP (1) | EP2462157B1 (sr) |
JP (2) | JP5791602B2 (sr) |
KR (1) | KR101415660B1 (sr) |
CN (2) | CN107188960A (sr) |
ES (1) | ES2817802T3 (sr) |
IN (1) | IN2012DN00338A (sr) |
SG (1) | SG177577A1 (sr) |
WO (1) | WO2011017514A1 (sr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2695889A1 (en) * | 2009-12-29 | 2014-02-12 | Dr. Reddy's Laboratories Limited | Protein purification by ion exchange |
WO2012015908A2 (en) | 2010-07-30 | 2012-02-02 | Millipore Corporation | Chromatography media and method |
US20120301429A1 (en) | 2011-05-27 | 2012-11-29 | Hartman Taymar E | Dac hyp compositions and methods |
CA2838476A1 (en) * | 2011-06-16 | 2012-12-20 | Dsm Ip Assets B.V. | Single unit chromatography antibody purification |
JP6280499B2 (ja) * | 2011-07-08 | 2018-02-14 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | Fc融合タンパク質の精製方法 |
BR112014001120A2 (pt) * | 2011-07-20 | 2017-02-21 | Zepteon Incorporated | métodos de separação de polipeptídeos |
JP2014527957A (ja) * | 2011-08-01 | 2014-10-23 | アヴァクシア バイオロジクス,インコーポレーテッド | ヒトtnfに特異的なウシポリクローナル抗体 |
US9096648B2 (en) * | 2011-08-19 | 2015-08-04 | Emd Millipore Corporation | Methods of reducing level of one or more impurities in a sample during protein purification |
AU2012301751A1 (en) * | 2011-09-01 | 2014-03-13 | Human Genome Sciences, Inc. | Viral clearance methods |
EP2578286A1 (en) | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Method and apparatus for chromatographic purification |
PL2773438T5 (pl) * | 2011-11-02 | 2022-01-17 | F.Hoffmann-La Roche Ag | Chromatografia przeciążenia i elucji |
WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
CN102492040B (zh) * | 2011-12-29 | 2014-06-25 | 嘉和生物药业有限公司 | 一种抗her2或/和抗her3抗体蛋白的纯化方法 |
SG10201701224UA (en) * | 2012-03-12 | 2017-04-27 | Merck Patent Gmbh | Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode |
EP2682168A1 (en) * | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
JP6253584B2 (ja) * | 2012-08-27 | 2017-12-27 | 旭化成メディカル株式会社 | 温度応答性クロマトグラフィーによる抗体の精製方法 |
LT2895188T (lt) | 2012-09-11 | 2018-04-10 | Coherus Biosciences, Inc. | Aukšto grynumo ir geros išeigos teisingos struktūros etanerceptas |
CN104968403A (zh) | 2012-09-17 | 2015-10-07 | 格雷斯公司 | 色谱介质和装置 |
EP2931301B2 (en) * | 2012-12-17 | 2021-09-15 | Merck Sharp & Dohme Corp. | Process for purifying insulin and analogues thereof |
JP2016507671A (ja) | 2013-02-14 | 2016-03-10 | ナノパレイル,エルエルシー | 電界紡糸ナノファイバーのハイブリッドフェルト |
CN105358572A (zh) * | 2013-05-06 | 2016-02-24 | 赛诺菲 | 用于纯化抗体的连续多步骤方法 |
WO2015035180A1 (en) * | 2013-09-05 | 2015-03-12 | Genentech, Inc. | Method for chromatography reuse |
WO2015041218A1 (ja) | 2013-09-17 | 2015-03-26 | 株式会社カネカ | 新規抗体精製方法及びそれから得られる抗体(Novel Antibody Purification Method and Antibody obtained therefrom)、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体(Novel Antibody Purification method using Cation Exchanger and Antibody obtained therefrom) |
EP3079808B1 (en) | 2013-12-12 | 2020-05-27 | EMD Millipore Corporation | Method of separating monomeric protein from protein agregates with a porous membrane comprising a co-polymer of benzyl acrylamide and acrylamide |
EP3105580B1 (en) * | 2014-02-14 | 2023-10-04 | Cytiva Sweden AB | Automated multi-step purification system |
WO2015135884A1 (en) * | 2014-03-10 | 2015-09-17 | Richter Gedeon Nyrt. | Immunoglobulin purification using pre-cleaning steps |
CN104826617B (zh) * | 2014-03-25 | 2017-06-13 | 西北大学 | 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法 |
PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
WO2015198320A1 (en) * | 2014-06-24 | 2015-12-30 | Insight Biopharmaceuticals Ltd. | Methods of purifying antibodies |
DE102014010353A1 (de) | 2014-07-10 | 2016-01-14 | Sartorius Stedim Biotech Gmbh | Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien |
CA2966515C (en) | 2014-12-08 | 2021-04-27 | Emd Millipore Corporation | Mixed bed ion exchange adsorber |
PL3302784T3 (pl) | 2015-06-05 | 2022-01-17 | W.R. Grace & Co.-Conn. | Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania |
CN109071598A (zh) * | 2016-04-05 | 2018-12-21 | 美国血液技术公司 | 从血液中富集免疫球蛋白的方法和装置 |
CN107964044B (zh) * | 2016-10-19 | 2021-11-19 | 无锡科捷诺生物科技有限责任公司 | 从乳样中纯化抗cd20单克隆抗体的方法 |
EP3769083A1 (en) | 2018-03-21 | 2021-01-27 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods |
WO2020125757A1 (en) * | 2018-12-21 | 2020-06-25 | Wuxi Biologics (Shanghai) Co., Ltd. | A method for improving aggregate removal by protein a chromatography |
FR3099066B1 (fr) * | 2019-07-26 | 2021-08-13 | Novasep Process | Procédé de purification d’une substance cible avec inactivation virale |
TW202128264A (zh) * | 2019-09-25 | 2021-08-01 | 瑞士商赫孚孟拉羅股份公司 | 使用經預測之溶離緩衝鹽濃度的陽離子層析法 |
CN110724204B (zh) * | 2019-11-18 | 2021-10-22 | 广东菲鹏制药股份有限公司 | Fc融合蛋白的纯化方法 |
CN113845562A (zh) * | 2020-06-28 | 2021-12-28 | 佛山汉腾生物科技有限公司 | 目的蛋白纯化方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4490937A (en) | 1981-12-07 | 1985-01-01 | Amcor Ltd. | Insect electrocution device |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5256694A (en) | 1984-09-22 | 1993-10-26 | Basf Aktiengesellschaft | Diarylacetylenes, their preparation and their use |
US5091178A (en) | 1986-02-21 | 1992-02-25 | Oncogen | Tumor therapy with biologically active anti-tumor antibodies |
US6054051A (en) | 1996-01-17 | 2000-04-25 | Genentech, Inc. | Tangential-flow filtration system |
PT1501369E (pt) | 2002-04-26 | 2015-09-21 | Genentech Inc | Purificação de proteínas com base na não afinidade |
AU2003262087B2 (en) * | 2002-09-11 | 2010-11-11 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
GB0304576D0 (en) | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
WO2006024497A1 (en) * | 2004-08-30 | 2006-03-09 | Lonza Biologics Plc. | Affinity- plus ion exchange- chromatography for purifying antibodies |
JP2010510963A (ja) * | 2006-06-14 | 2010-04-08 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | セラミックヒドロキシアパタイトを使用する抗体の精製方法 |
WO2008025747A1 (en) * | 2006-08-28 | 2008-03-06 | Ares Trading S.A. | Process for the purification of fc-fusion proteins |
EP2061803B2 (en) * | 2006-08-28 | 2022-11-16 | Ares Trading S.A. | Process for the purification of fc-containing proteins |
JP2010516651A (ja) * | 2007-01-17 | 2010-05-20 | メルク セローノ ソシエテ アノニム | Fc含有タンパク質の精製のための方法 |
US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
WO2009045897A1 (en) | 2007-10-03 | 2009-04-09 | Dyax Corp. | Systems and methods for purifying proteins |
CN102027010A (zh) | 2008-05-15 | 2011-04-20 | 诺沃-诺迪斯克有限公司 | 抗体纯化方法 |
MX2011004201A (es) * | 2008-10-20 | 2011-05-24 | Abbott Lab | Desactivacion viral durante purificacion de anticuerpos. |
-
2010
- 2010-08-05 IN IN338DEN2012 patent/IN2012DN00338A/en unknown
- 2010-08-05 CN CN201710418825.9A patent/CN107188960A/zh active Pending
- 2010-08-05 KR KR1020127001161A patent/KR101415660B1/ko active IP Right Grant
- 2010-08-05 US US12/851,082 patent/US8536316B2/en active Active
- 2010-08-05 WO PCT/US2010/044539 patent/WO2011017514A1/en active Application Filing
- 2010-08-05 CN CN201080035153.XA patent/CN102574911B/zh not_active Expired - Fee Related
- 2010-08-05 JP JP2012523945A patent/JP5791602B2/ja not_active Expired - Fee Related
- 2010-08-05 SG SG2012001483A patent/SG177577A1/en unknown
- 2010-08-05 ES ES10807153T patent/ES2817802T3/es active Active
- 2010-08-05 EP EP10807153.1A patent/EP2462157B1/en active Active
-
2015
- 2015-05-01 JP JP2015093970A patent/JP6335838B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2462157A4 (en) | 2012-12-26 |
ES2817802T3 (es) | 2021-04-08 |
EP2462157A1 (en) | 2012-06-13 |
WO2011017514A1 (en) | 2011-02-10 |
JP2015157846A (ja) | 2015-09-03 |
JP5791602B2 (ja) | 2015-10-07 |
JP6335838B2 (ja) | 2018-05-30 |
KR20120089432A (ko) | 2012-08-10 |
US8536316B2 (en) | 2013-09-17 |
CN102574911A (zh) | 2012-07-11 |
CN102574911B (zh) | 2017-06-06 |
JP2013501721A (ja) | 2013-01-17 |
US20110065901A1 (en) | 2011-03-17 |
SG177577A1 (en) | 2012-03-29 |
EP2462157B1 (en) | 2020-06-17 |
KR101415660B1 (ko) | 2014-07-16 |
CN107188960A (zh) | 2017-09-22 |
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