IN2012DN00302A - - Google Patents

Info

Publication number
IN2012DN00302A
IN2012DN00302A IN302DEN2012A IN2012DN00302A IN 2012DN00302 A IN2012DN00302 A IN 2012DN00302A IN 302DEN2012 A IN302DEN2012 A IN 302DEN2012A IN 2012DN00302 A IN2012DN00302 A IN 2012DN00302A
Authority
IN
India
Prior art keywords
enzyme
mgs
methylglyoxal synthase
mutant
biochemical
Prior art date
Application number
Other languages
English (en)
Inventor
Francois Voelker
Laurence Dumon-Seignovert
Philippe Soucaille
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of IN2012DN00302A publication Critical patent/IN2012DN00302A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03003—Methylglyoxal synthase (4.2.3.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
IN302DEN2012 2009-07-30 2010-07-30 IN2012DN00302A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23007609P 2009-07-30 2009-07-30
EP09166815 2009-07-30
PCT/EP2010/061094 WO2011012693A1 (fr) 2009-07-30 2010-07-30 Méthylglyoxal synthétase (mgs) mutante pour la production d'un agent biochimique par fermentation

Publications (1)

Publication Number Publication Date
IN2012DN00302A true IN2012DN00302A (fr) 2015-05-08

Family

ID=41014566

Family Applications (1)

Application Number Title Priority Date Filing Date
IN302DEN2012 IN2012DN00302A (fr) 2009-07-30 2010-07-30

Country Status (9)

Country Link
US (1) US8497102B2 (fr)
EP (1) EP2459710B1 (fr)
JP (1) JP5913099B2 (fr)
KR (1) KR101771266B1 (fr)
CN (1) CN102575235B (fr)
BR (1) BR112012002153A2 (fr)
CA (1) CA2767962C (fr)
IN (1) IN2012DN00302A (fr)
WO (1) WO2011012693A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2532751A1 (fr) 2011-06-10 2012-12-12 Metabolic Explorer Utilisation de promoteurs inductibles dans la production fermentative de 1,2-propanediol
CA2839373A1 (fr) 2011-06-15 2012-12-20 B.R.A.I.N. Biotechnology Research And Information Network Ag Nouveaux moyens et procedes de production de propanediol
US9745556B2 (en) 2011-10-04 2017-08-29 University Of Florida Research Foundation, Incorporated Variants of glycerol dehydrogenase having D-lactate dehydrogenase activity and uses thereof
US11072807B2 (en) * 2012-09-14 2021-07-27 Ptt Global Chemical Public Company Limited Production of organic acids by fermentation of genetically engineered yeast cells at low pH
CN102994577B (zh) * 2012-10-26 2015-01-21 上海交通大学 微生物细胞转化法生产丙酮醇的方法
JP6446807B2 (ja) * 2014-03-26 2019-01-09 三菱ケミカル株式会社 微生物を用いた有機化合物の製造方法
EP3347478B1 (fr) 2015-09-10 2022-09-21 Metabolic Explorer Nouvelles lactaldéhydes réductases pour la production de 1,2-propanédiol
EP3342873A1 (fr) 2016-12-29 2018-07-04 Metabolic Explorer Conversion de méthylglyoxale en hydroxyacétone utilisant des enzymes et applications associées
KR102488646B1 (ko) * 2020-04-02 2023-01-16 서강대학교산학협력단 스트렙-태그를 포함하는 오셔니써머스 프로펀더스 dsm 14977 균주 유래 초고내열성 메틸글라이옥살 합성효소 및 이를 이용한 메틸글라이옥살의 제조 방법
KR102489629B1 (ko) * 2020-04-02 2023-01-18 서강대학교산학협력단 스트렙-태그를 포함하는 클로스트리디움 디피실리 630 균주 유래 메틸글라이옥살 합성효소 및 이를 이용한 메틸글라이옥살의 제조 방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336051A1 (de) 1983-10-04 1985-04-25 Maizena Gmbh, 2000 Hamburg Verfahren zur herstellung von 1,2-propandiol, insbesondere d(-)-1,2-propandiol
DE3820040A1 (de) 1988-06-13 1989-12-14 Henkel Kgaa Verfahren und vorrichtung zum abtrennen von propylenglykol
DE4128692A1 (de) 1991-08-29 1993-03-04 Henkel Kgaa Verfahren zum herstellen von acetol
WO1999028481A1 (fr) 1997-02-19 1999-06-10 Wisconsin Alumni Research Foundation Production microbienne d'hydroxyacetone et de 1,2-propanediol
US6087140A (en) 1997-02-19 2000-07-11 Wisconsin Alumni Research Foundation Microbial production of 1,2-propanediol from sugar
EP1513940A4 (fr) 2002-05-30 2006-10-25 Cargill Dow Llc Procedes et materiaux permettant la production d'acide lactique dans des levures
US7300787B2 (en) 2002-07-05 2007-11-27 Archer-Daniels-Midland Company Lactobacillus strains and use thereof in fermentation for L-lactic acid production
KR100864672B1 (ko) 2003-04-02 2008-10-23 씨제이제일제당 (주) 클렙시엘라 뉴모니아를 이용한 1,2-프로판디올의 생산방법
JP4473219B2 (ja) 2003-09-30 2010-06-02 三井化学株式会社 Ｄ−乳酸生産用生体触媒
US20050112737A1 (en) 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
EP2298721B1 (fr) 2004-03-25 2014-06-04 Galen J. Suppes Procédé pour préparer une composition antigel contenant d'alcools inférieurs et du glycérol par alcoolyse d'une glycéride
ES2401339T3 (es) 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
RU2412929C9 (ru) 2005-12-29 2012-04-10 Басф Се Способ выделения пропиленгликоля из водных композиций
WO2008116849A1 (fr) 2007-03-23 2008-10-02 Metabolic Explorer Nouveaux micro-organismes servant à produire acétol au moyen d'une combinaison évolutive et rationnelle
CN101679940A (zh) 2007-03-23 2010-03-24 代谢探索者公司 用于产生1,2-丙二醇的代谢工程改造的微生物
WO2008116851A1 (fr) 2007-03-23 2008-10-02 Metabolic Explorer Micro-organisme obtenu par génie métabolique utile pour produire acétol
JP5570821B2 (ja) 2007-03-23 2014-08-13 メタボリック エクスプローラー 進化と合理的設計の組合せによって得られた、１，２−プロパンジオールの製造のための新規微生物

Also Published As

Publication number Publication date
EP2459710A1 (fr) 2012-06-06
US8497102B2 (en) 2013-07-30
BR112012002153A2 (pt) 2015-09-15
KR101771266B1 (ko) 2017-08-24
US20120122166A1 (en) 2012-05-17
JP2013500032A (ja) 2013-01-07
EP2459710B1 (fr) 2016-11-09
CA2767962A1 (fr) 2011-02-03
JP5913099B2 (ja) 2016-04-27
WO2011012693A1 (fr) 2011-02-03
CN102575235A (zh) 2012-07-11
CA2767962C (fr) 2017-11-28
KR20120047276A (ko) 2012-05-11
CN102575235B (zh) 2015-05-20

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