IN170659B - - Google Patents

Info

Publication number
IN170659B
IN170659B IN383/DEL/89A IN383DE1989A IN170659B IN 170659 B IN170659 B IN 170659B IN 383DE1989 A IN383DE1989 A IN 383DE1989A IN 170659 B IN170659 B IN 170659B
Authority
IN
India
Application number
IN383/DEL/89A
Other languages
English (en)
Inventor
Hector Floyd Deluca
Heinrich Konstantive Schnoes
Kato Lenard Perlman
Andrzej Kutner
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IN170659B publication Critical patent/IN170659B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IN383/DEL/89A 1988-04-29 1989-05-01 IN170659B (browse.php)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/187,680 US4927815A (en) 1988-04-29 1988-04-29 Compounds effective in inducing cell differentiation and process for preparing same

Publications (1)

Publication Number Publication Date
IN170659B true IN170659B (browse.php) 1992-05-02

Family

ID=22690003

Family Applications (1)

Application Number Title Priority Date Filing Date
IN383/DEL/89A IN170659B (browse.php) 1988-04-29 1989-05-01

Country Status (15)

Country Link
US (2) US4927815A (browse.php)
EP (1) EP0375757A1 (browse.php)
JP (2) JPH0725730B2 (browse.php)
KR (1) KR930011151B1 (browse.php)
AU (1) AU630096B2 (browse.php)
CA (1) CA1340615C (browse.php)
DK (2) DK666589A (browse.php)
FR (1) FR2630740A1 (browse.php)
GB (1) GB2217715A (browse.php)
HU (1) HU206083B (browse.php)
IE (1) IE67868B1 (browse.php)
IL (1) IL90066A (browse.php)
IN (1) IN170659B (browse.php)
NL (1) NL8920414A (browse.php)
WO (1) WO1989010353A1 (browse.php)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
CA1339383C (en) * 1989-03-09 1997-08-26 Hector Floyd Deluca Method for preparing intermediates for the synthesis of steroid side chains in optically active form
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
RU2123338C1 (ru) * 1990-06-15 1998-12-20 Сайтел Корпорейшн Фармацевтическая композиция на основе медиатора межклеточной адгезии (варианты), способ ингибирования межклеточной адгезии, способ лечения воспалительного заболевания, способ анализа тестируемого соединения на способность ингибировать клеточную адгезию, способ получения соединения
US5276061A (en) * 1990-08-24 1994-01-04 Wisconsin Alumni Research Foundation Cosmetic compositions containing 1α-hydroxyvitamin D homologs
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
DE4221961A1 (de) * 1992-06-30 1994-01-05 Schering Ag 22-En-25-oxa-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, diese Derivate enthaltenen pharmazeutische Präparate sowie deren Verwendung als Arzneimittel
US5380720A (en) * 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
AU683112B2 (en) * 1993-12-01 1997-10-30 Sankyo Company Limited Inflammatory cytokine production inhibitor containing polyprenyl derivative as active ingredient
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
US5744128A (en) * 1995-05-03 1998-04-28 Holick; Michael F. Use of emu oil for stimulating skin and hair growth
IL118156A (en) * 1995-05-09 2001-08-26 Duphar Int Res Vitamin d compounds, their preparation and pharmaceutical compositions containing them
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
EP2340840B1 (en) * 1998-03-27 2012-08-29 Oregon Health Sciences University Pulse dose Vitamin D drug for the treatment of hyperproliferative skin diseases
ES2614632T3 (es) * 1999-04-01 2017-06-01 Johns Hopkins University Análogos no calcémicos, antiproliferativos, transcripcionalmente activos de 1-alfa 25-dihidroxi vitamina D3 que contienen azufre
AU2058701A (en) 1999-12-02 2001-06-12 F. Hoffmann-La Roche Ag Esters of vitamin D3 and uses thereof
US7166585B2 (en) * 2001-08-22 2007-01-23 Cytochroma Inc. 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3
EP1497264A2 (en) * 2002-04-11 2005-01-19 Instytut Farmaceutyczny Preparation of 24-alkyl analogs of cholecalciferol and non-racemic compounds
EP1737468A2 (en) 2004-03-01 2007-01-03 Bioxell S.p.a. Treatment of interstitial cystitis with vitamin d compounds
JP2008519808A (ja) 2004-11-12 2008-06-12 ビオエクセル エスピーエー 膀胱癌治療のためのビタミンd誘導体及び抗増殖薬の併用
EP2144872A2 (en) * 2007-04-18 2010-01-20 Johns Hopkins University Low calcemic, highly antiproliferative, analogs of calcitriol
WO2010088304A1 (en) 2009-01-27 2010-08-05 Cytotech Labs, Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CA2770683C (en) 2009-08-14 2018-09-04 Berg Biosystems, Llc Vitamin d3 and analogs thereof for treating alopecia
WO2012065050A1 (en) 2010-11-12 2012-05-18 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
CN110981765A (zh) * 2019-11-07 2020-04-10 肇庆巨元生化有限公司 一种25-羟基维生素d3中间体的制备方法
CN112920096A (zh) * 2019-12-05 2021-06-08 四川大学 一种制备2-甲基-4-(苯磺酰基)-2-丁醇的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500301A (ja) * 1984-10-04 1987-02-05 ウイスコンシン アラムナイ リサ−チ フオンデ−シヨン 24―ホモビタミンd誘導体
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
DE3687377T2 (de) * 1985-01-17 1993-04-29 Wisconsin Alumni Res Found Vitamin-d-abkoemmlinge und deren herstellungsverfahren.
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
WO1989010351A1 (en) * 1988-04-21 1989-11-02 Leo Pharmaceutical Products Ltd. A/S (Løvens Kemis Novel vitamin d analogues
RU2057117C1 (ru) * 1988-04-29 1996-03-27 Висконсин Алюмни Рисерч Фаундейшн ГОМОЛОГИ 1α - ГИДРОКСИВИТАМИНА D3 С НЕНАСЫЩЕННОЙ БОКОВОЙ ЦЕПЬЮ, КОМПОЗИЦИЯ, СПОСОБСТВУЮЩАЯ СТИМУЛЯЦИИ И УСИЛЕНИЮ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА, СПОСОБ СТИМУЛЯЦИИ И УСИЛЕНИЯ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА

Also Published As

Publication number Publication date
KR930011151B1 (ko) 1993-11-24
IE67868B1 (en) 1996-05-01
JPH0748343A (ja) 1995-02-21
US5061699A (en) 1991-10-29
IE891406L (en) 1989-10-29
CA1340615C (en) 1999-06-29
WO1989010353A1 (en) 1989-11-02
JP2505713B2 (ja) 1996-06-12
KR900700449A (ko) 1990-08-13
AU3573089A (en) 1989-11-24
EP0375757A1 (en) 1990-07-04
DK89091A (da) 1991-05-13
HU892989D0 (en) 1990-06-28
HU206083B (en) 1992-08-28
IL90066A0 (en) 1989-12-15
DK666589A (da) 1990-02-28
DK89091D0 (da) 1991-05-13
DK666589D0 (da) 1989-12-22
AU630096B2 (en) 1992-10-22
FR2630740A1 (fr) 1989-11-03
NL8920414A (nl) 1990-04-02
JPH02504154A (ja) 1990-11-29
IL90066A (en) 1995-12-08
GB8909570D0 (en) 1989-06-14
GB2217715A (en) 1989-11-01
JPH0725730B2 (ja) 1995-03-22
US4927815A (en) 1990-05-22
HUT52475A (en) 1990-07-28

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