IN163939B - - Google Patents

Info

Publication number
IN163939B
IN163939B IN174/MAS/87A IN174MA1987A IN163939B IN 163939 B IN163939 B IN 163939B IN 174MA1987 A IN174MA1987 A IN 174MA1987A IN 163939 B IN163939 B IN 163939B
Authority
IN
India
Prior art keywords
compaction
ibuprofen
composition
crystalline ibuprofen
crystalline
Prior art date
Application number
IN174/MAS/87A
Other languages
English (en)
Inventor
Allan Keith
Wesley Bogan David
Chen Jivn-Ren
Michael Slater Richard
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of IN163939B publication Critical patent/IN163939B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polyurethanes Or Polyureas (AREA)
IN174/MAS/87A 1986-03-19 1987-03-12 IN163939B (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868606762A GB8606762D0 (en) 1986-03-19 1986-03-19 Therapeutic agents

Publications (1)

Publication Number Publication Date
IN163939B true IN163939B (fi) 1988-12-10

Family

ID=10594868

Family Applications (1)

Application Number Title Priority Date Filing Date
IN174/MAS/87A IN163939B (fi) 1986-03-19 1987-03-12

Country Status (21)

Country Link
EP (1) EP0241126B1 (fi)
JP (1) JPS62230723A (fi)
KR (1) KR870008582A (fi)
CN (1) CN87101974A (fi)
AT (1) ATE65393T1 (fi)
AU (1) AU7017787A (fi)
CS (1) CS182787A2 (fi)
DD (1) DD263232A5 (fi)
DE (1) DE3771544D1 (fi)
DK (1) DK136487A (fi)
FI (1) FI871112A (fi)
GB (2) GB8606762D0 (fi)
HU (1) HU195422B (fi)
IL (1) IL81884A0 (fi)
IN (1) IN163939B (fi)
NO (1) NO871120L (fi)
NZ (1) NZ219560A (fi)
PL (1) PL264695A1 (fi)
PT (1) PT84526B (fi)
YU (1) YU47087A (fi)
ZA (1) ZA871836B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833448A1 (de) * 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
CA2063141C (en) * 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
WO1993013756A1 (en) * 1992-01-10 1993-07-22 Obschestvo S Ogranichennoy Otvetstvennostyu Meditsinsky Nauchno-Proizvodstvennoy Komplex 'biotiki' Granulated pharmaceutical composition and method of obtaining it
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
PL175564B1 (pl) * 1993-10-01 1999-01-29 Astra Ab Sposób i urządzenie do formowania leku w proszku oraz lek w proszku
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
FR2804603B1 (fr) * 2000-02-04 2004-01-23 Rhodia Chimie Sa Procede continu pour formuler sous forme de granules une ou plusieurs matieres actives pharmaceutiques
DE102005037630A1 (de) 2005-08-09 2007-02-15 Glatt Gmbh Verfahren zur Herstellung von Teilchen aus pharmazeutischen Substanzen, Teilchen aus pharmazeutischen Substanzen sowie deren Verwendung
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476248A (en) * 1983-02-28 1984-10-09 The Upjohn Company Crystallization of ibuprofen
JPS60120616A (ja) * 1983-12-05 1985-06-28 Yaskawa Electric Mfg Co Ltd プリセット型可逆カウンタ装置
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing

Also Published As

Publication number Publication date
EP0241126B1 (en) 1991-07-24
ZA871836B (en) 1987-09-02
DD263232A5 (de) 1988-12-28
CS182787A2 (en) 1991-05-14
GB8704987D0 (en) 1987-04-08
PT84526A (en) 1987-04-01
NO871120L (no) 1987-09-21
DK136487A (da) 1987-09-20
DK136487D0 (da) 1987-03-17
ATE65393T1 (de) 1991-08-15
NO871120D0 (no) 1987-03-18
PL264695A1 (en) 1988-05-12
EP0241126A1 (en) 1987-10-14
JPS62230723A (ja) 1987-10-09
GB2187952A (en) 1987-09-23
GB8606762D0 (en) 1986-04-23
FI871112A0 (fi) 1987-03-13
PT84526B (pt) 1989-11-10
NZ219560A (en) 1989-05-29
IL81884A0 (en) 1987-10-20
KR870008582A (ko) 1987-10-19
DE3771544D1 (de) 1991-08-29
HUT42939A (en) 1987-09-28
AU7017787A (en) 1987-09-24
FI871112A (fi) 1987-09-20
CN87101974A (zh) 1987-10-21
YU47087A (en) 1988-04-30
HU195422B (en) 1988-05-30
GB2187952B (en) 1990-05-09

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