IL98224A - 6-Substituted purine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

6-Substituted purine derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL98224A
IL98224A IL9822491A IL9822491A IL98224A IL 98224 A IL98224 A IL 98224A IL 9822491 A IL9822491 A IL 9822491A IL 9822491 A IL9822491 A IL 9822491A IL 98224 A IL98224 A IL 98224A
Authority
IL
Israel
Prior art keywords
compound
formula
phenyl
alkyl
propanylthio
Prior art date
Application number
IL9822491A
Other languages
English (en)
Other versions
IL98224A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL98224A0 publication Critical patent/IL98224A0/xx
Publication of IL98224A publication Critical patent/IL98224A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL9822491A 1990-05-23 1991-05-22 6-Substituted purine derivatives, their preparation and pharmaceutical compositions containing them IL98224A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52762590A 1990-05-23 1990-05-23

Publications (2)

Publication Number Publication Date
IL98224A0 IL98224A0 (en) 1992-06-21
IL98224A true IL98224A (en) 1995-07-31

Family

ID=24102273

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9822491A IL98224A (en) 1990-05-23 1991-05-22 6-Substituted purine derivatives, their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
EP (1) EP0458618A1 (enExample)
JP (1) JPH04226986A (enExample)
KR (1) KR910020011A (enExample)
CN (1) CN1031642C (enExample)
AU (1) AU636034B2 (enExample)
CA (1) CA2042944A1 (enExample)
FI (1) FI912486A7 (enExample)
HU (1) HUT57768A (enExample)
IE (1) IE911751A1 (enExample)
IL (1) IL98224A (enExample)
MY (1) MY106167A (enExample)
NO (1) NO179909C (enExample)
NZ (1) NZ238122A (enExample)
PT (1) PT97741B (enExample)
TN (1) TNSN91037A1 (enExample)
TW (1) TW211012B (enExample)
ZA (1) ZA913880B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU648070B2 (en) * 1990-04-23 1994-04-14 Ortho Pharmaceutical Corporation Process for preparing optically active isomers of 6-substituted purinyl piperazine derivatives
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
ATE311884T1 (de) * 1997-07-12 2005-12-15 Cancer Rec Tech Ltd Cyclin-abhängige-kinase inhibierende purinderivate
ES2329595T3 (es) * 2004-05-12 2009-11-27 Bayer Cropscience Ag Regulacion del crecimiento de las plantas.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2334009A1 (de) * 1973-07-04 1975-01-23 Boehringer Mannheim Gmbh Purin-derivate sowie verfahren zu ihrer herstellung
DE3703633A1 (de) * 1986-02-14 1987-08-20 Sandoz Ag Purin-derivate, ihre herstellung und sie enthaltende arzneimittel
US4876257A (en) * 1988-03-03 1989-10-24 Ortho Pharmaceutical Corporation 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents

Also Published As

Publication number Publication date
JPH04226986A (ja) 1992-08-17
NZ238122A (en) 1994-01-26
EP0458618A1 (en) 1991-11-27
AU7723391A (en) 1991-11-28
PT97741A (pt) 1992-02-28
AU636034B2 (en) 1993-04-08
NO179909C (no) 1997-01-08
MY106167A (en) 1995-03-31
FI912486L (fi) 1991-11-24
NO911973L (no) 1991-11-25
NO179909B (no) 1996-09-30
NO911973D0 (no) 1991-05-22
CA2042944A1 (en) 1991-11-24
PT97741B (pt) 1998-10-30
ZA913880B (en) 1993-01-27
IL98224A0 (en) 1992-06-21
FI912486A7 (fi) 1991-11-24
IE911751A1 (en) 1991-12-04
HUT57768A (en) 1991-12-30
CN1031642C (zh) 1996-04-24
TW211012B (enExample) 1993-08-11
FI912486A0 (fi) 1991-05-22
KR910020011A (ko) 1991-12-19
CN1057463A (zh) 1992-01-01
TNSN91037A1 (fr) 1992-10-25

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Legal Events

Date Code Title Description
RH Patent void