IL98071A0 - 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,processes for their preparation and their use as antiprotozoal and antiviral agents - Google Patents

9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,processes for their preparation and their use as antiprotozoal and antiviral agents

Info

Publication number
IL98071A0
IL98071A0 IL98071A IL9807191A IL98071A0 IL 98071 A0 IL98071 A0 IL 98071A0 IL 98071 A IL98071 A IL 98071A IL 9807191 A IL9807191 A IL 9807191A IL 98071 A0 IL98071 A0 IL 98071A0
Authority
IL
Israel
Prior art keywords
trimethylfurano
undecahydro
11alpha
6alpha
3alpha
Prior art date
Application number
IL98071A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL98071A0 publication Critical patent/IL98071A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL98071A 1990-05-07 1991-05-06 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,processes for their preparation and their use as antiprotozoal and antiviral agents IL98071A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90108580 1990-05-07

Publications (1)

Publication Number Publication Date
IL98071A0 true IL98071A0 (en) 1992-06-21

Family

ID=8203955

Family Applications (1)

Application Number Title Priority Date Filing Date
IL98071A IL98071A0 (en) 1990-05-07 1991-05-06 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,processes for their preparation and their use as antiprotozoal and antiviral agents

Country Status (11)

Country Link
US (1) US5246930A (ja)
EP (1) EP0456149A1 (ja)
JP (1) JPH04225983A (ja)
KR (1) KR920005722A (ja)
AU (1) AU639095B2 (ja)
BR (1) BR9101822A (ja)
IE (1) IE911529A1 (ja)
IL (1) IL98071A0 (ja)
PT (1) PT97577A (ja)
TW (1) TW198722B (ja)
ZA (1) ZA913393B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07500325A (ja) * 1991-10-14 1995-01-12 ザ ユニバーシティ オブ シドニー 環状パーオキシアセタール化合物
RU2236413C2 (ru) 1998-07-14 2004-09-20 Байер Акциенгезельшафт Производные артемизинина, способ их получения, фармацевтическая композиция на их основе и способ лечения
IN191696B (ja) * 1999-02-12 2003-12-20 Council Scient Ind Res
US7842719B2 (en) 2002-10-31 2010-11-30 Kemin Foods, L.C. Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus
US20110206636A1 (en) * 2003-09-16 2011-08-25 Kemin Foods, LLC Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus
CN1311832C (zh) * 2005-01-12 2007-04-25 四川科伦药业股份有限公司 溴代二氢青蒿素的医药用途
CN103159777A (zh) * 2013-03-05 2013-06-19 华东师范大学 一种卤代青蒿素衍生物的合成方法
CN104086560A (zh) * 2014-07-03 2014-10-08 唐心建 卤代青蒿素母核、卤代青蒿素衍生物、卤代双氢青蒿素、卤代脱羰青蒿素以及医药用途
CN107011356A (zh) * 2017-06-08 2017-08-04 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 一种脱水双氢青蒿素的合成方法
CN110981887B (zh) * 2019-09-12 2022-05-17 延边大学 一类二氢青蒿素类化合物及其制备方法和医用用途
KR102266875B1 (ko) * 2019-12-12 2021-06-18 대한민국 감자 바이러스 y 방제용 화합물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH679486A5 (ja) * 1986-12-18 1992-02-28 Stanford Res Inst Int
US4963683A (en) * 1986-12-18 1990-10-16 Sri International Process for preparing polyoxa tetracyclic compounds
GB8804372D0 (en) * 1988-02-25 1988-03-23 World Health Org Synthesis of dihydroqinghaosu derivatives
EP0362730A1 (en) * 1988-10-04 1990-04-11 Hoechst Aktiengesellschaft Artemisinin derivatives, processes for their preparation and their use as antiprotozoal agents

Also Published As

Publication number Publication date
IE911529A1 (en) 1991-11-20
US5246930A (en) 1993-09-21
EP0456149A1 (en) 1991-11-13
BR9101822A (pt) 1991-12-17
PT97577A (pt) 1992-01-31
JPH04225983A (ja) 1992-08-14
KR920005722A (ko) 1992-04-03
TW198722B (ja) 1993-01-21
AU639095B2 (en) 1993-07-15
AU7618591A (en) 1991-11-07
ZA913393B (en) 1992-02-26

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IL98071A0 (en) 9-substituted compounds of 3alpha,11alpha-epoxy-3,4,5,5a alpha,6,7,8,8a,9,11,11a-undecahydro-3beta,6alpha,9-trimethylfurano(3,4-j)(1,2)-benzodioxepin,processes for their preparation and their use as antiprotozoal and antiviral agents
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