ZA874036B - Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents - Google Patents

Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents

Info

Publication number
ZA874036B
ZA874036B ZA874036A ZA874036A ZA874036B ZA 874036 B ZA874036 B ZA 874036B ZA 874036 A ZA874036 A ZA 874036A ZA 874036 A ZA874036 A ZA 874036A ZA 874036 B ZA874036 B ZA 874036B
Authority
ZA
South Africa
Prior art keywords
pyrridazino
isoquinolines
cardioprotective
pyrrolo
amino
Prior art date
Application number
ZA874036A
Inventor
Walter Loesel
Loesel Walter
Otto Roos
Roos Otto
Gerd Schnorrenberg
Schnorrenberg Gerd
Dietrich Arndts
Arndts Dietrich
George Speck
Speck George
Helmut Ensinger
Ensinger Helmut
Franz-Josef Kuhn
Kuhn Franz-Josef
Erich Lehr
Lehr Erich
Dieter Hinzen
Hinzen Dieter
Guenter Schingnitz
Schingnitz Guenter
Richard Reichl
Reichl Richard
Ilse Streller
Streller Ilse
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA874036B publication Critical patent/ZA874036B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA874036A 1986-06-06 1987-06-05 Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents ZA874036B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863619099 DE3619099A1 (en) 1986-06-06 1986-06-06 USE OF 12-AMINO-PYRRIDAZINO (4 ', 5': 3,4) PYRROLO- (2,1-A) -ISOCHINOLINES AS A CARDIO- AND NEUROPROTECTIVE AGENT

Publications (1)

Publication Number Publication Date
ZA874036B true ZA874036B (en) 1989-02-22

Family

ID=6302443

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874036A ZA874036B (en) 1986-06-06 1987-06-05 Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents

Country Status (4)

Country Link
EP (1) EP0252299A3 (en)
JP (1) JPH07116040B2 (en)
DE (1) DE3619099A1 (en)
ZA (1) ZA874036B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3468520B2 (en) * 1992-06-22 2003-11-17 ベーリンガー インゲルハイム コマンディトゲゼルシャフト 9-Amino-pyridazino [4 ', 5': 3,4] pyrrolo [2,1-a] isoquinoline and use of the compound in the manufacture of pharmaceutical preparations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3401018A1 (en) * 1984-01-13 1985-07-18 Boehringer Ingelheim KG, 6507 Ingelheim METHOD FOR PRODUCING 5,6-DIHYDRO-PYRROLO (2,1-A) ISOCHINOLINES
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
DE8502008U1 (en) * 1985-01-26 1985-08-29 Celamerck Gmbh & Co Kg, 6507 Ingelheim Closure cap for two-component packs

Also Published As

Publication number Publication date
JPH07116040B2 (en) 1995-12-13
DE3619099A1 (en) 1987-12-10
JPS63115879A (en) 1988-05-20
EP0252299A3 (en) 1990-04-11
EP0252299A2 (en) 1988-01-13

Similar Documents

Publication Publication Date Title
IL81672A0 (en) N,n'-dihalo-2-imidazolidinones and their use as disinfectants
AU7315587A (en) Sportman's article of equipment
AR245210A1 (en) Thickened hypochlorite composition and use thereof
IL81793A0 (en) C(29)-acyloxy-milbemycin derivatives,their preparation and their use as pesticides
IL83034A (en) Alpha-aryl-alpha-phenylethyl-1h-1,2,4-triazole-1-propanenitriles,their preparation and their use as fungicides
GB2194237B (en) 1,2,2,6, 6-pentamethyl-4-piperidylaminotriazine derivatives and their use as stabilizers
NZ220453A (en) 1,2,3,6-tetrahydro-5-nitro-pyridine derivatives and pesticidal compositions
IL95946A0 (en) Preparation of tetrabromo-4,4'-alkylidenediphenols
AU589463B2 (en) Assistant combination and use thereof as textile finishing agent
PH24904A (en) N-substituted-arylalkyl and arylalkylene aminoheterocyclics as antisectory agents
IL81706A0 (en) N'-substituted-n-acyl-n'-alkyl-carbonylhydrazines and their use as insecticides
IL82242A0 (en) N-substituted-n'-substituted-n,n'-diacylhydrazines and their use as insecticides
NZ223200A (en) Anthelmintic compositions containing 2',5-dicloro-4'-nitrosalicylanilide and non aqueous carrier
AU7746887A (en) The use of SCR'S in extending retarding
GB8923820D0 (en) Compound,composition,process and use
AR242084A1 (en) Bactericidal composition and use thereof
IL81409A0 (en) Substituted n-phenyl-n'-benzoyl-ureas,their preparation and their use as pesticides
AR242798A1 (en) Steroido {3,2-c] pyrazoles useful as antiandrogenic agents and preparation thereof
NZ219719A (en) Endo-4-amino-5-chloro-2-methoxy-n-cl-azabicyclo -(3,3,1)-non-4-yl)-benzamide and pharmaceutical compositions
ZA874036B (en) Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents
PH27414A (en) 1,2,4-oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents
EP0238357A3 (en) 1,2,4-triazinone derivatives, their preparation and use
ZA86659B (en) 6-chloro-3-methyl-1h-2,3,4,5-tetrahydro-3-benzazepine-n-oxide and medical compositions using it
IL81293A0 (en) 2,4-diamine-6-haloalkylpyridines,their preparation and their use as herbicides
IL82797A0 (en) 2-phenylacetyl-1,3,5-cyclohexanetriones,their preparation and their use as herbicides