IL96734A - תרכיבי רוקחות תרסיסיים המכילים אוטואנטיגנים - Google Patents

תרכיבי רוקחות תרסיסיים המכילים אוטואנטיגנים

Info

Publication number
IL96734A
IL96734A IL9673490A IL9673490A IL96734A IL 96734 A IL96734 A IL 96734A IL 9673490 A IL9673490 A IL 9673490A IL 9673490 A IL9673490 A IL 9673490A IL 96734 A IL96734 A IL 96734A
Authority
IL
Israel
Prior art keywords
mbp
aerosol
disease
autoimmune
administration
Prior art date
Application number
IL9673490A
Other languages
English (en)
Other versions
IL96734A0 (en
Original Assignee
Brigham & Womens Hospital
Autoimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital, Autoimmune Inc filed Critical Brigham & Womens Hospital
Publication of IL96734A0 publication Critical patent/IL96734A0/xx
Publication of IL96734A publication Critical patent/IL96734A/he

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9673490A 1989-12-20 1990-12-20 תרכיבי רוקחות תרסיסיים המכילים אוטואנטיגנים IL96734A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45480689A 1989-12-20 1989-12-20

Publications (2)

Publication Number Publication Date
IL96734A0 IL96734A0 (en) 1991-09-16
IL96734A true IL96734A (he) 1996-11-14

Family

ID=23806184

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9673490A IL96734A (he) 1989-12-20 1990-12-20 תרכיבי רוקחות תרסיסיים המכילים אוטואנטיגנים

Country Status (14)

Country Link
EP (1) EP0506785B1 (he)
JP (1) JP2625253B2 (he)
KR (1) KR0185747B1 (he)
AT (1) ATE190496T1 (he)
AU (1) AU642693B2 (he)
BR (1) BR9007950A (he)
CA (1) CA2070281C (he)
DE (1) DE69033487T2 (he)
DK (1) DK0506785T3 (he)
ES (1) ES2144398T3 (he)
GR (1) GR3033634T3 (he)
HU (2) HUT61487A (he)
IL (1) IL96734A (he)
WO (1) WO1991008760A1 (he)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843445A (en) * 1987-06-24 1998-12-01 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
US5849298A (en) * 1987-06-24 1998-12-15 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of bovine myelin
US5869054A (en) * 1987-06-24 1999-02-09 Autoimmune Inc. Treatment of multiple sclerosis by oral administration of autoantigens
US6645504B1 (en) 1987-06-24 2003-11-11 Autoimmune Inc. Bystander suppression of type I diabetes by oral administration of glucagon
ATE158950T1 (de) * 1989-07-14 1997-10-15 Autoimmune Inc Behandlung der autoimmunen uveoretinitis in menschen
IL99699A (he) * 1990-10-10 2002-04-21 Autoimmune Inc תרופה עם אפשרות מינון בדרך הפה, תוך-מעי, או ע" י שאיפה עבור דיכוי תגובה אוטואימונית הקשורה לסוכרת מסוג i
EP0553291B1 (en) * 1990-10-15 2006-03-08 Autoimmune, Inc. Treatment of autoimmune diseases by oral administration of autoantigens
DE69332518T2 (de) * 1992-02-28 2003-09-04 Autoimmune Inc Unterdrückung von autoimmunkrankheiten durch antigene in wartestellung
JP3845447B2 (ja) * 1992-09-25 2006-11-15 オートイミューン インク タイプ▲ii▼コラーゲンによるリウマチ性関節炎治療方法
CA2164326A1 (en) * 1993-06-02 1994-12-08 Wayne Robert Thomas Cryptic peptides for use in inducing immunologic tolerance
HUT77047A (hu) * 1994-10-25 1998-03-02 Immulogic Pharmaceutical Corporation Szklerózis multiplex kezelésére szolgáló készítmények és kezelések
US6488933B2 (en) 1995-07-05 2002-12-03 Yeda Research And Development Co. Ltd. Preparations for the treatment of T cell mediated diseases
US5856446A (en) * 1995-07-07 1999-01-05 Autoimmune Inc. Method of treating rheumatoid arthritis with low dose type II collagen
JP3935938B2 (ja) * 1996-01-05 2007-06-27 オートイミューン インク ▲ii▼型コラーゲンの調製法
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
CA2275889C (en) 1996-12-30 2008-03-18 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
US7097845B2 (en) 1997-04-23 2006-08-29 Jacob Sten Petersen Combinations of antigen and mucosal binding component for inducing specific immunological tolerance
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US6743427B1 (en) 1997-12-02 2004-06-01 Neuralab Limited Prevention and treatment of amyloidogenic disease
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US6750324B1 (en) 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US6923964B1 (en) 1997-12-02 2005-08-02 Neuralab Limited Active immunization of AScr for prion disorders
US6710226B1 (en) 1997-12-02 2004-03-23 Neuralab Limited Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
US6913745B1 (en) 1997-12-02 2005-07-05 Neuralab Limited Passive immunization of Alzheimer's disease
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
US6787637B1 (en) 1999-05-28 2004-09-07 Neuralab Limited N-Terminal amyloid-β antibodies
UA81216C2 (en) 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
SE9902155L (sv) * 1999-06-09 2000-12-10 Bjoern Rydevik Serum antibodies
EP1286686B1 (en) 2000-05-24 2007-07-25 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES E-selectin for treating or preventing stroke
US7897575B2 (en) 2000-05-24 2011-03-01 The United States Of America As Represented By The Department Of Health And Human Services Treatment and prevention of vascular dementia
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
DE10230381A1 (de) 2002-07-05 2004-01-22 Institut für Medizintechnologie Magdeburg GmbH, IMTM Verwendung von Inhibitoren der Alanyl-Aminopeptidasen und diese umfassende pharmazeutischen Zubereitungen
WO2004024906A1 (en) 2002-09-13 2004-03-25 UNIVERSITé LAVAL Nucleoside triphosphate diphosphohydrolase (ntpdase 8) and uses thereof
TWI374893B (en) 2003-05-30 2012-10-21 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
CA2590337C (en) 2004-12-15 2017-07-11 Neuralab Limited Humanized amyloid beta antibodies for use in improving cognition
CN101365714A (zh) 2005-07-01 2009-02-11 福赛特儿童口腔医院 结核抗原的检测分析及疫苗
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
PT2182983E (pt) 2007-07-27 2014-09-01 Janssen Alzheimer Immunotherap Tratamento de doenças amiloidogénicas com anticorpos anti-abeta humanizados
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies
US20130236484A1 (en) 2012-03-08 2013-09-12 Detectogen Inc. Leishmaniasis antigen detection assays and vaccines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US379778A (en) * 1888-03-20 Machine for mitering printers rules
US65734A (en) * 1867-06-11 Joseph fantou
DE3856566T2 (de) * 1987-06-24 2004-06-24 Brigham And Women's Hospital, Boston Behandlung von Autoimmun-Erkrankungen durch orale Verabreichung von Autoantigenen
KR900700617A (ko) * 1988-04-08 1990-08-16 브루스 엠. 에이센 뼈 및 연골 유도 조성물

Also Published As

Publication number Publication date
DK0506785T3 (da) 2000-07-24
CA2070281A1 (en) 1991-06-21
IL96734A0 (en) 1991-09-16
EP0506785A4 (en) 1993-09-08
HU9202072D0 (en) 1992-09-28
WO1991008760A1 (en) 1991-06-27
JP2625253B2 (ja) 1997-07-02
AU642693B2 (en) 1993-10-28
KR920703081A (ko) 1992-12-17
AU6979191A (en) 1991-07-18
HUT61487A (en) 1993-01-28
KR0185747B1 (ko) 1999-05-01
BR9007950A (pt) 1992-10-27
DE69033487T2 (de) 2000-06-29
GR3033634T3 (en) 2000-10-31
ES2144398T3 (es) 2000-06-16
JPH05504341A (ja) 1993-07-08
EP0506785A1 (en) 1992-10-07
HU210715A9 (en) 1995-06-28
CA2070281C (en) 2005-08-23
DE69033487D1 (de) 2000-04-20
EP0506785B1 (en) 2000-03-15
ATE190496T1 (de) 2000-04-15

Similar Documents

Publication Publication Date Title
EP0506785B1 (en) Improved treatment of autoimmune diseases by aerosol administration of auto antigens
US5645820A (en) Treatment of autoimmune diseases by aerosol administration of autoantigens
US5571500A (en) Treatment of autoimmune diseases through administration by inhalation of autoantigens
US5571499A (en) Treatment of autoimmune diseases by aerosol administration of autoantigens
US5641474A (en) Prevention of autoimmune diseases by aerosol administration of autoantigens
AU720695B2 (en) Bystander suppression of autoimmune diseases
EP1033998B1 (en) Suppressing beta-amyloid-related changes in alzheimer's disease
US5783188A (en) Method of treating rheumatoid arthritis with type collagen peptide fragments containing repeating sequences
US6645504B1 (en) Bystander suppression of type I diabetes by oral administration of glucagon
WO1994007520A9 (en) Method of treating rheumatoid arthritis with type ii collagen
Friedman et al. Oral tolerance: a biologically relevant pathway to generate peripheral tolerance against external and self antigens
WO1994007520A1 (en) Method of treating rheumatoid arthritis with type ii collagen
IL97446A (he) תכשיר תרופתי לשיפור של דאון-רגולציהשל מחלות חיסוניות-עצמיות
US5935577A (en) Treatment of autoimmune disease using tolerization in combination with methotrexate
KR20000070460A (ko) 메토트렉세이트와 공동으로 내성화를 사용한 자기면역질병의 치료
WO1998032451A9 (en) Treatment of autoimmune disease using tolerization in combination with methotrexate
US20010007758A1 (en) Treatment of multiple sclerosis using COP-1 and Th2-enhancing cytokines
JPH09511745A (ja) 経口寛容および/またはタイプiインターフェロンを用いた自己免疫疾患の治療
CA2410563C (en) Methods for preventing strokes by inducing tolerance to e-selectin
AU2001264813A1 (en) Methods for preventing strokes by inducing tolerance to E-selectin
EP1842551A1 (en) E-selectin for treating or preventing stroke
EP0662838A1 (en) Method of treating rheumatoid arthritis with type ii collagen
US20040115217A1 (en) Bystander suppression of autoimmune diseases

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired