IL93893A - History of imidazo-) A-2,1 (purine and imidazo) C-1,2 (pyridazo) E -4,3 (pyramidine transformed in the fall, selectivity for adenosine receptor and raw preparations - Google Patents

History of imidazo-) A-2,1 (purine and imidazo) C-1,2 (pyridazo) E -4,3 (pyramidine transformed in the fall, selectivity for adenosine receptor and raw preparations

Info

Publication number
IL93893A
IL93893A IL9389390A IL9389390A IL93893A IL 93893 A IL93893 A IL 93893A IL 9389390 A IL9389390 A IL 9389390A IL 9389390 A IL9389390 A IL 9389390A IL 93893 A IL93893 A IL 93893A
Authority
IL
Israel
Prior art keywords
phenyl
hydrogen
dihydro
compound according
adenosine
Prior art date
Application number
IL9389390A
Other languages
English (en)
Hebrew (he)
Other versions
IL93893A0 (en
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of IL93893A0 publication Critical patent/IL93893A0/xx
Publication of IL93893A publication Critical patent/IL93893A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
IL9389390A 1989-03-29 1990-03-26 History of imidazo-) A-2,1 (purine and imidazo) C-1,2 (pyridazo) E -4,3 (pyramidine transformed in the fall, selectivity for adenosine receptor and raw preparations IL93893A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33040089A 1989-03-29 1989-03-29

Publications (2)

Publication Number Publication Date
IL93893A0 IL93893A0 (en) 1990-12-23
IL93893A true IL93893A (en) 1994-07-31

Family

ID=23289598

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9389390A IL93893A (en) 1989-03-29 1990-03-26 History of imidazo-) A-2,1 (purine and imidazo) C-1,2 (pyridazo) E -4,3 (pyramidine transformed in the fall, selectivity for adenosine receptor and raw preparations

Country Status (18)

Country Link
EP (1) EP0390111B1 (sv)
JP (1) JP3014000B2 (sv)
KR (1) KR0150635B1 (sv)
CN (1) CN1029972C (sv)
AR (1) AR245720A1 (sv)
AT (1) ATE111466T1 (sv)
AU (1) AU623755B2 (sv)
CA (1) CA2013381C (sv)
DE (1) DE69012388T2 (sv)
ES (1) ES2063851T3 (sv)
FI (1) FI95133C (sv)
HU (1) HU203349B (sv)
IE (1) IE63545B1 (sv)
IL (1) IL93893A (sv)
NO (1) NO173997C (sv)
NZ (1) NZ233077A (sv)
PT (1) PT93589B (sv)
ZA (1) ZA902282B (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270316A (en) * 1989-10-20 1993-12-14 Kyowa Hakko Kogyo Co., Ltd. Condensed purine derivatives
ZA914727B (en) * 1990-06-21 1992-03-25 Schering Corp Polycyclic guanine derivatives
DE19629378A1 (de) * 1996-07-20 1998-01-29 Boehringer Ingelheim Kg Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP1251130B1 (en) 1999-12-24 2005-02-16 Kyowa Hakko Kogyo Co., Ltd. Fused purine derivatives

Also Published As

Publication number Publication date
DE69012388T2 (de) 1995-04-27
KR900014390A (ko) 1990-10-23
FI95133B (sv) 1995-09-15
HUT54160A (en) 1991-01-28
JPH02289574A (ja) 1990-11-29
CN1045974A (zh) 1990-10-10
KR0150635B1 (ko) 1998-10-15
NO173997B (no) 1993-11-22
IE63545B1 (en) 1995-05-17
CA2013381A1 (en) 1990-09-29
AU5218290A (en) 1990-10-04
NO901424L (no) 1990-10-01
PT93589B (pt) 1996-06-28
AU623755B2 (en) 1992-05-21
DE69012388D1 (de) 1994-10-20
ZA902282B (en) 1990-12-28
NZ233077A (en) 1992-12-23
ES2063851T3 (es) 1995-01-16
ATE111466T1 (de) 1994-09-15
NO901424D0 (no) 1990-03-28
CA2013381C (en) 2000-06-20
JP3014000B2 (ja) 2000-02-28
CN1029972C (zh) 1995-10-11
FI901550A0 (sv) 1990-03-28
HU901857D0 (en) 1990-08-28
HU203349B (en) 1991-07-29
EP0390111B1 (en) 1994-09-14
IL93893A0 (en) 1990-12-23
IE901142L (en) 1990-09-29
EP0390111A2 (en) 1990-10-03
FI95133C (sv) 1995-12-27
EP0390111A3 (en) 1991-05-08
PT93589A (pt) 1990-11-20
AR245720A1 (es) 1994-02-28
NO173997C (no) 1994-03-02

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.