IL93136A - History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them - Google Patents
History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL93136A IL93136A IL9313690A IL9313690A IL93136A IL 93136 A IL93136 A IL 93136A IL 9313690 A IL9313690 A IL 9313690A IL 9313690 A IL9313690 A IL 9313690A IL 93136 A IL93136 A IL 93136A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- hydrogen
- parts
- amino
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898904108A GB8904108D0 (en) | 1989-02-23 | 1989-02-23 | Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones |
GB898920354A GB8920354D0 (en) | 1989-09-08 | 1989-09-08 | Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones |
US40662689A | 1989-09-13 | 1989-09-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL93136A0 IL93136A0 (en) | 1990-11-05 |
IL93136A true IL93136A (en) | 1995-01-24 |
Family
ID=27264337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9313690A IL93136A (en) | 1989-02-23 | 1990-01-23 | History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0384522B1 (es) |
JP (1) | JP2588624B2 (es) |
AP (1) | AP139A (es) |
AT (1) | ATE84534T1 (es) |
AU (1) | AU617926B2 (es) |
CA (1) | CA2010639C (es) |
CY (1) | CY1868A (es) |
DE (1) | DE69000743T2 (es) |
DK (1) | DK0384522T3 (es) |
EG (1) | EG19674A (es) |
ES (1) | ES2046671T3 (es) |
FI (1) | FI92830C (es) |
GR (1) | GR3006855T3 (es) |
HK (1) | HK114995A (es) |
HU (2) | HU204831B (es) |
IE (1) | IE63155B1 (es) |
IL (1) | IL93136A (es) |
JO (1) | JO1610B1 (es) |
LV (1) | LV5782B4 (es) |
MA (1) | MA21748A1 (es) |
MY (1) | MY106231A (es) |
NO (1) | NO173503C (es) |
NZ (1) | NZ232548A (es) |
OA (1) | OA09196A (es) |
PH (1) | PH27113A (es) |
PT (1) | PT93227B (es) |
TN (1) | TNSN90021A1 (es) |
YU (1) | YU47219B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8806449D0 (en) * | 1988-03-18 | 1988-04-20 | Janssen Pharmaceutica Nv | Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones |
NZ235137A (en) * | 1989-09-13 | 1992-02-25 | Janssen Pharmaceutica Nv | Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof |
NZ238664A (en) * | 1990-07-06 | 1992-12-23 | Janssen Pharmaceutica Nv | Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions |
DE4036552C1 (es) * | 1990-11-16 | 1992-02-06 | Boehringer Mannheim Gmbh, 6800 Mannheim, De | |
DE4103803A1 (de) * | 1991-02-08 | 1992-08-13 | Boehringer Mannheim Gmbh | Neue 4,5,6,7-tetrahydro-imidazo-(4,5,ljk)(1,4)- benzodiazepin-2-(1h)-thione, verfahren zu ihrer herstellung sowie arzneimittel und zwischenprodukte zur herstellung dieser verbindungen |
GB9109557D0 (en) * | 1991-05-02 | 1991-06-26 | Wellcome Found | Chemical compounds |
WO1992020344A1 (en) * | 1991-05-16 | 1992-11-26 | Glaxo Group Limited | Antiviral combinations containing nucleoside analogs |
IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
US5593993A (en) * | 1991-08-02 | 1997-01-14 | Medivir Ab | Method for inhibition of HIV related viruses |
US5463049A (en) * | 1991-09-24 | 1995-10-31 | Janssen Pharmaceutica N.V. | Process for preparing enantiomerically pure imidazo[4,5,1-JK][1,4]-benzodiazepin-2(1H)-thiones |
DK0639971T3 (da) * | 1992-05-13 | 2000-03-20 | Wellcome Found | Terapeutiske kombinationer |
US6177435B1 (en) | 1992-05-13 | 2001-01-23 | Glaxo Wellcome Inc. | Therapeutic combinations |
GR920100326A (el) * | 1992-07-21 | 1994-03-31 | Medivir Ag | Ενώσεις και μέ?οδοι αναστολής του HIV και των σχετικών ιών. |
US5519021A (en) * | 1992-08-07 | 1996-05-21 | Merck & Co., Inc. | Benzoxazinones as inhibitors of HIV reverse transcriptase |
DE19946289A1 (de) * | 1999-09-28 | 2001-03-29 | Basf Ag | Benzodiazepin-Derivate, deren Herstellung und Anwendung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4075206A (en) * | 1977-02-25 | 1978-02-21 | Eli Lilly And Company | Substituted pyrroloquinoxalinones and diones |
FR2534257A1 (fr) * | 1982-10-12 | 1984-04-13 | Roussel Uclaf | Nouveaux derives de la 6-amino 7-hydroxy 4,5,6,7-tetrahydro-imidazo/4,5,1-j-k/ /1/ benzazepin-2(1h)-one, leurs sels, application a titre de medicaments, compositions les renfermant et un intermediaire |
GB8333581D0 (en) * | 1983-12-16 | 1984-01-25 | Wyeth John & Brother Ltd | Heterocyclic compounds |
GB8806449D0 (en) * | 1988-03-18 | 1988-04-20 | Janssen Pharmaceutica Nv | Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones |
-
1990
- 1990-01-23 IL IL9313690A patent/IL93136A/en not_active IP Right Cessation
- 1990-02-06 MY MYPI90000182A patent/MY106231A/en unknown
- 1990-02-14 NZ NZ232548A patent/NZ232548A/en unknown
- 1990-02-16 AT AT90200348T patent/ATE84534T1/de not_active IP Right Cessation
- 1990-02-16 EP EP90200348A patent/EP0384522B1/en not_active Expired - Lifetime
- 1990-02-16 ES ES199090200348T patent/ES2046671T3/es not_active Expired - Lifetime
- 1990-02-16 DK DK90200348.2T patent/DK0384522T3/da active
- 1990-02-16 DE DE9090200348T patent/DE69000743T2/de not_active Expired - Fee Related
- 1990-02-19 MA MA22010A patent/MA21748A1/fr unknown
- 1990-02-20 YU YU33490A patent/YU47219B/sh unknown
- 1990-02-20 JO JO19901610A patent/JO1610B1/en active
- 1990-02-21 EG EG11190A patent/EG19674A/xx active
- 1990-02-21 AP APAP/P/1990/000166A patent/AP139A/en active
- 1990-02-22 PT PT93227A patent/PT93227B/pt not_active IP Right Cessation
- 1990-02-22 FI FI900897A patent/FI92830C/fi not_active IP Right Cessation
- 1990-02-22 TN TNTNSN90021A patent/TNSN90021A1/fr unknown
- 1990-02-22 NO NO900848A patent/NO173503C/no unknown
- 1990-02-22 CA CA002010639A patent/CA2010639C/en not_active Expired - Fee Related
- 1990-02-22 IE IE65090A patent/IE63155B1/en not_active IP Right Cessation
- 1990-02-22 AU AU50038/90A patent/AU617926B2/en not_active Ceased
- 1990-02-22 HU HU90896A patent/HU204831B/hu not_active IP Right Cessation
- 1990-02-22 JP JP2039883A patent/JP2588624B2/ja not_active Expired - Fee Related
- 1990-02-23 PH PH40105A patent/PH27113A/en unknown
- 1990-02-23 OA OA59740A patent/OA09196A/xx unknown
-
1993
- 1993-01-21 GR GR930400107T patent/GR3006855T3/el unknown
-
1995
- 1995-06-28 HU HU95P/P00504P patent/HU211250A9/hu unknown
- 1995-07-13 HK HK114995A patent/HK114995A/xx not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY186896A patent/CY1868A/xx unknown
- 1996-06-18 LV LV960193A patent/LV5782B4/xx unknown
Also Published As
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AP139A (en) | Antiviral tetrahydroimidazo[1,4]benzodiazepin-2-thiones. | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |