IL92799A - תולדת בנזימידאזול, תהליך להכנתה ותכשירים תרופתיים המעכבים חומצת קיבה המכילים אותה - Google Patents
תולדת בנזימידאזול, תהליך להכנתה ותכשירים תרופתיים המעכבים חומצת קיבה המכילים אותהInfo
- Publication number
- IL92799A IL92799A IL9279989A IL9279989A IL92799A IL 92799 A IL92799 A IL 92799A IL 9279989 A IL9279989 A IL 9279989A IL 9279989 A IL9279989 A IL 9279989A IL 92799 A IL92799 A IL 92799A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- compound according
- benzimidazole
- man
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Percussion Or Vibration Massage (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19888804629A SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | New therapeutically active compounds |
SE8902170A SE8902170D0 (sv) | 1989-06-16 | 1989-06-16 | Therapeutically active compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
IL92799A0 IL92799A0 (en) | 1990-09-17 |
IL92799A true IL92799A (he) | 1994-01-25 |
Family
ID=26660387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9279989A IL92799A (he) | 1988-12-22 | 1989-12-19 | תולדת בנזימידאזול, תהליך להכנתה ותכשירים תרופתיים המעכבים חומצת קיבה המכילים אותה |
Country Status (27)
Country | Link |
---|---|
US (1) | US5025024A (he) |
EP (1) | EP0449935B1 (he) |
JP (1) | JP2793905B2 (he) |
KR (1) | KR910700248A (he) |
CN (1) | CN1028233C (he) |
AT (1) | ATE110723T1 (he) |
AU (1) | AU639429B2 (he) |
BG (1) | BG60101B2 (he) |
CA (1) | CA2005980C (he) |
CS (1) | CS276361B6 (he) |
DE (1) | DE68917937T2 (he) |
DK (1) | DK122191A (he) |
EG (1) | EG19302A (he) |
FI (1) | FI913034A0 (he) |
GR (1) | GR1000316B (he) |
HU (1) | HUT57204A (he) |
IE (1) | IE64199B1 (he) |
IL (1) | IL92799A (he) |
LV (1) | LV10267B (he) |
MY (1) | MY129946A (he) |
NO (1) | NO178336C (he) |
NZ (1) | NZ231874A (he) |
PH (1) | PH27446A (he) |
PL (1) | PL160767B1 (he) |
PT (1) | PT92649B (he) |
WO (1) | WO1990006924A1 (he) |
YU (1) | YU47338B (he) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
CA2472103A1 (en) * | 2002-01-25 | 2003-08-07 | Santarus, Inc. | Transmucosal delivery of proton pump inhibitors |
EP1603537A4 (en) * | 2003-02-20 | 2009-11-04 | Santarus Inc | IMMEDIATE RELEASE OF OMEPRAZOLE ANTACIDAL COMPLEX WITH NEW FORMULATION FOR RAPID AND PROLONGED ELIMINATION OF GASTRIC ACID |
AU2004257864A1 (en) * | 2003-07-18 | 2005-01-27 | Santarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
JP2006528181A (ja) * | 2003-07-18 | 2006-12-14 | サンタラス インコーポレイティッド | 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法 |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
IN148930B (he) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
HU195220B (en) * | 1983-05-03 | 1988-04-28 | Byk Gulden Lomberg Chem Fqb | Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them |
JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
SE8505112D0 (sv) * | 1985-10-29 | 1985-10-29 | Haessle Ab | Novel pharmacological compounds |
FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
NZ222495A (en) * | 1986-11-21 | 1991-04-26 | Haessle Ab | Benzimidazole derivatives and pharmaceutical compositions |
FI96860C (fi) * | 1987-06-17 | 1996-09-10 | Eisai Co Ltd | Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi |
-
1989
- 1989-12-18 IE IE405089A patent/IE64199B1/en not_active IP Right Cessation
- 1989-12-18 EG EG61989A patent/EG19302A/xx active
- 1989-12-19 NZ NZ231874A patent/NZ231874A/en unknown
- 1989-12-19 IL IL9279989A patent/IL92799A/he not_active IP Right Cessation
- 1989-12-19 PH PH39731A patent/PH27446A/en unknown
- 1989-12-19 GR GR890100833A patent/GR1000316B/el unknown
- 1989-12-19 CA CA002005980A patent/CA2005980C/en not_active Expired - Lifetime
- 1989-12-20 AU AU48132/90A patent/AU639429B2/en not_active Ceased
- 1989-12-20 JP JP2501536A patent/JP2793905B2/ja not_active Expired - Fee Related
- 1989-12-20 EP EP90901073A patent/EP0449935B1/en not_active Expired - Lifetime
- 1989-12-20 US US07/453,960 patent/US5025024A/en not_active Expired - Lifetime
- 1989-12-20 WO PCT/SE1989/000739 patent/WO1990006924A1/en active IP Right Grant
- 1989-12-20 AT AT90901073T patent/ATE110723T1/de not_active IP Right Cessation
- 1989-12-20 DE DE68917937T patent/DE68917937T2/de not_active Expired - Fee Related
- 1989-12-20 HU HU901095A patent/HUT57204A/hu not_active IP Right Cessation
- 1989-12-20 KR KR1019900701827A patent/KR910700248A/ko not_active Application Discontinuation
- 1989-12-21 PT PT92649A patent/PT92649B/pt not_active IP Right Cessation
- 1989-12-21 CN CN89109589A patent/CN1028233C/zh not_active Expired - Fee Related
- 1989-12-21 YU YU242789A patent/YU47338B/sh unknown
- 1989-12-21 MY MYPI89001835A patent/MY129946A/en unknown
- 1989-12-22 CS CS897343A patent/CS276361B6/cs unknown
- 1989-12-22 PL PL1989282922A patent/PL160767B1/pl unknown
-
1991
- 1991-06-19 BG BG094657A patent/BG60101B2/bg unknown
- 1991-06-20 FI FI913034A patent/FI913034A0/fi not_active Application Discontinuation
- 1991-06-20 NO NO912414A patent/NO178336C/no unknown
- 1991-06-21 DK DK122191A patent/DK122191A/da unknown
-
1993
- 1993-06-28 LV LVP-93-691A patent/LV10267B/lv unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |