IL92463A - Quinoxaline compounds, their preparation and pharmaceutical compositions containing them - Google Patents

Quinoxaline compounds, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL92463A
IL92463A IL9246389A IL9246389A IL92463A IL 92463 A IL92463 A IL 92463A IL 9246389 A IL9246389 A IL 9246389A IL 9246389 A IL9246389 A IL 9246389A IL 92463 A IL92463 A IL 92463A
Authority
IL
Israel
Prior art keywords
mmol
dione
hydroxy
solution
give
Prior art date
Application number
IL9246389A
Other languages
English (en)
Other versions
IL92463A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL92463A0 publication Critical patent/IL92463A0/xx
Publication of IL92463A publication Critical patent/IL92463A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Television Signal Processing For Recording (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9246389A 1988-12-22 1989-11-27 Quinoxaline compounds, their preparation and pharmaceutical compositions containing them IL92463A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK715888A DK715888D0 (da) 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
IL92463A0 IL92463A0 (en) 1990-08-31
IL92463A true IL92463A (en) 1995-03-15

Family

ID=8149230

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9246389A IL92463A (en) 1988-12-22 1989-11-27 Quinoxaline compounds, their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US5061706A (de)
EP (1) EP0377112B1 (de)
JP (1) JPH02221263A (de)
AT (1) ATE110371T1 (de)
AU (1) AU626093B2 (de)
CA (1) CA2004078A1 (de)
DE (1) DE68917708T2 (de)
DK (1) DK715888D0 (de)
ES (1) ES2058450T3 (de)
FI (1) FI896235A0 (de)
IE (1) IE66561B1 (de)
IL (1) IL92463A (de)
NO (1) NO178661C (de)
NZ (1) NZ231906A (de)
PT (1) PT92714B (de)
ZA (1) ZA899469B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
EP0556393B1 (de) * 1990-11-06 2000-07-26 Yamanouchi Pharmaceutical Co. Ltd. Kondensiertes pyrazinderivat
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
AU672617B2 (en) * 1992-06-22 1996-10-10 Regents Of The University Of California, The Glycine receptor antagonists and the use thereof
US5631373A (en) 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
DE4340045A1 (de) * 1993-11-24 1995-06-01 Basf Ag Neue Chinoxaline und Arzneimittel daraus
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
DE4428152A1 (de) * 1994-06-22 1996-01-04 Basf Ag Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
EP0705834A1 (de) * 1994-07-27 1996-04-10 Ciba-Geigy Ag Azaaliphatisch Überbrückte Chinoxalin-2,3-dione
EP0705835A1 (de) * 1994-09-01 1996-04-10 Ciba-Geigy Ag Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione
GB9418443D0 (en) * 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19624808A1 (de) 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
AU3166897A (en) * 1996-06-24 1998-01-14 Novo Nordisk A/S Factor vii-binding reagent
EP0963372A1 (de) * 1997-02-18 1999-12-15 American Home Products Corporation 5-aminoalkoxy-1,4-dihydrochinoxalin-2,3-dione als dopamin agonsisten
US5922715A (en) * 1997-02-18 1999-07-13 American Home Products Corporation 5-aminoalkoxy-1, 4-dihydroquinoxaline-2, 3-diones
EP2338492A1 (de) 2009-12-24 2011-06-29 Universidad del Pais Vasco Verfahren und Zusammensetzung zur Behandlung von Alzheimer
EP3427729A1 (de) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992378A (en) * 1973-12-26 1976-11-16 Eli Lilly And Company Fluoralkyl quinoxadinediones
US4812458A (en) * 1986-09-16 1989-03-14 A/S Ferrosan 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser

Also Published As

Publication number Publication date
NO895193L (no) 1990-06-25
NZ231906A (en) 1991-11-26
US5061706A (en) 1991-10-29
DK715888D0 (da) 1988-12-22
IL92463A0 (en) 1990-08-31
EP0377112B1 (de) 1994-08-24
IE66561B1 (en) 1996-01-24
FI896235A0 (fi) 1989-12-22
DE68917708T2 (de) 1994-12-15
DE68917708D1 (de) 1994-09-29
CA2004078A1 (en) 1990-06-22
JPH02221263A (ja) 1990-09-04
NO178661C (no) 1996-05-08
ZA899469B (en) 1990-09-26
EP0377112A1 (de) 1990-07-11
PT92714A (pt) 1990-06-29
PT92714B (pt) 1996-01-31
IE893749L (en) 1990-06-22
AU626093B2 (en) 1992-07-23
NO178661B (no) 1996-01-29
AU4687289A (en) 1990-06-28
ES2058450T3 (es) 1994-11-01
ATE110371T1 (de) 1994-09-15
NO895193D0 (no) 1989-12-21

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US5081123A (en) Quinoxaline compound and their preparation and use
US4948794A (en) Cycloalkyl or benzyl-6-substituted-quinoxalinediones
US5061706A (en) 2,3-quinoxalinediones for use as neuroleptics
US4912108A (en) Pyridoquinoxaline compounds and their preparation and use as glutamate antagonists
US5109001A (en) Fused 2,3-dihydroxydiazolo compounds and their preparation and use
AU652560B2 (en) Quinoxaline compounds and their preparation and use
US4812458A (en) 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics
CA1298298C (en) Quinoxaline compounds and their preparation and use
US5308845A (en) Quinoxaline compounds and their preparation and use
EP0511152A2 (de) Quinoxalin-Verbindungen, ihre Herstellung und Verwendung
US5153195A (en) Quinoxaline compounds and their preparation and use
DK165294B (da) Quinoxalinforbindelser, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne

Legal Events

Date Code Title Description
RH Patent void