DE68917708D1 - Chinoxalin-Verbindungen, ihre Herstellung und Verwendung. - Google Patents

Chinoxalin-Verbindungen, ihre Herstellung und Verwendung.

Info

Publication number
DE68917708D1
DE68917708D1 DE68917708T DE68917708T DE68917708D1 DE 68917708 D1 DE68917708 D1 DE 68917708D1 DE 68917708 T DE68917708 T DE 68917708T DE 68917708 T DE68917708 T DE 68917708T DE 68917708 D1 DE68917708 D1 DE 68917708D1
Authority
DE
Germany
Prior art keywords
compounds
production
hydrogen
quinoxaline compounds
so2nr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68917708T
Other languages
English (en)
Other versions
DE68917708T2 (de
Inventor
Tage Honore
Poul Jacobsen
Flemming Elmelund Nielsen
Lars Naerum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE68917708D1 publication Critical patent/DE68917708D1/de
Application granted granted Critical
Publication of DE68917708T2 publication Critical patent/DE68917708T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE68917708T 1988-12-22 1989-11-28 Chinoxalin-Verbindungen, ihre Herstellung und Verwendung. Expired - Fee Related DE68917708T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK715888A DK715888D0 (da) 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse

Publications (2)

Publication Number Publication Date
DE68917708D1 true DE68917708D1 (de) 1994-09-29
DE68917708T2 DE68917708T2 (de) 1994-12-15

Family

ID=8149230

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917708T Expired - Fee Related DE68917708T2 (de) 1988-12-22 1989-11-28 Chinoxalin-Verbindungen, ihre Herstellung und Verwendung.

Country Status (16)

Country Link
US (1) US5061706A (de)
EP (1) EP0377112B1 (de)
JP (1) JPH02221263A (de)
AT (1) ATE110371T1 (de)
AU (1) AU626093B2 (de)
CA (1) CA2004078A1 (de)
DE (1) DE68917708T2 (de)
DK (1) DK715888D0 (de)
ES (1) ES2058450T3 (de)
FI (1) FI896235A0 (de)
IE (1) IE66561B1 (de)
IL (1) IL92463A (de)
NO (1) NO178661C (de)
NZ (1) NZ231906A (de)
PT (1) PT92714B (de)
ZA (1) ZA899469B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
JP2550456B2 (ja) * 1990-11-06 1996-11-06 山之内製薬株式会社 縮合ピラジン誘導体
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
DE4340045A1 (de) * 1993-11-24 1995-06-01 Basf Ag Neue Chinoxaline und Arzneimittel daraus
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
DE4428152A1 (de) * 1994-06-22 1996-01-04 Basf Ag Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
EP0705834A1 (de) * 1994-07-27 1996-04-10 Ciba-Geigy Ag Azaaliphatisch Überbrückte Chinoxalin-2,3-dione
EP0705835A1 (de) * 1994-09-01 1996-04-10 Ciba-Geigy Ag Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione
GB9418443D0 (en) * 1994-09-13 1994-11-02 Pfizer Ltd Therapeutic agents
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19624808A1 (de) 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
AU3166897A (en) * 1996-06-24 1998-01-14 Novo Nordisk A/S Factor vii-binding reagent
US5922715A (en) * 1997-02-18 1999-07-13 American Home Products Corporation 5-aminoalkoxy-1, 4-dihydroquinoxaline-2, 3-diones
EP0963372A1 (de) * 1997-02-18 1999-12-15 American Home Products Corporation 5-aminoalkoxy-1,4-dihydrochinoxalin-2,3-dione als dopamin agonsisten
EP2338492A1 (de) 2009-12-24 2011-06-29 Universidad del Pais Vasco Verfahren und Zusammensetzung zur Behandlung von Alzheimer
EP3427729A1 (de) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992378A (en) * 1973-12-26 1976-11-16 Eli Lilly And Company Fluoralkyl quinoxadinediones
US4812458A (en) * 1986-09-16 1989-03-14 A/S Ferrosan 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser

Also Published As

Publication number Publication date
AU4687289A (en) 1990-06-28
CA2004078A1 (en) 1990-06-22
FI896235A0 (fi) 1989-12-22
AU626093B2 (en) 1992-07-23
IL92463A (en) 1995-03-15
DK715888D0 (da) 1988-12-22
ATE110371T1 (de) 1994-09-15
PT92714A (pt) 1990-06-29
EP0377112A1 (de) 1990-07-11
NO895193L (no) 1990-06-25
NO178661C (no) 1996-05-08
PT92714B (pt) 1996-01-31
EP0377112B1 (de) 1994-08-24
ZA899469B (en) 1990-09-26
JPH02221263A (ja) 1990-09-04
IE893749L (en) 1990-06-22
ES2058450T3 (es) 1994-11-01
US5061706A (en) 1991-10-29
IE66561B1 (en) 1996-01-24
NZ231906A (en) 1991-11-26
NO895193D0 (no) 1989-12-21
IL92463A0 (en) 1990-08-31
DE68917708T2 (de) 1994-12-15
NO178661B (no) 1996-01-29

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Publication Publication Date Title
DE68916626D1 (de) Chinoxalin-Verbindungen, ihre Herstellung und Verwendung.
DE68917708T2 (de) Chinoxalin-Verbindungen, ihre Herstellung und Verwendung.
DE3888093D1 (de) Chinoxalinverbindungen und deren Herstellung und Verwendung.
DE69120400D1 (de) Chinoxalinverbindungen, herstellung und verwendung
DE3788612T2 (de) Chinoxalin-Verbindungen und deren Herstellung und Verwendung.
DE3853043T2 (de) Isochinolinderivate, ihre Herstellung und Verwendung.
FI844232A0 (fi) Purinderivat.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee