IL91704A0 - Imidazoline derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Imidazoline derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL91704A0 IL91704A0 IL91704A IL9170489A IL91704A0 IL 91704 A0 IL91704 A0 IL 91704A0 IL 91704 A IL91704 A IL 91704A IL 9170489 A IL9170489 A IL 9170489A IL 91704 A0 IL91704 A0 IL 91704A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- imidazoline derivatives
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63253391A JPH02101065A (ja) | 1988-10-06 | 1988-10-06 | イミダゾリン誘導体及びその製法 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL91704A0 true IL91704A0 (en) | 1990-06-10 |
Family
ID=17250719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL91704A IL91704A0 (en) | 1988-10-06 | 1989-09-20 | Imidazoline derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (17)
Country | Link |
---|---|
US (1) | US5051441A (fi) |
EP (1) | EP0363061B1 (fi) |
JP (1) | JPH02101065A (fi) |
KR (1) | KR960009570B1 (fi) |
CN (1) | CN1020096C (fi) |
AT (1) | ATE78470T1 (fi) |
AU (1) | AU611827B2 (fi) |
CA (1) | CA1330997C (fi) |
DE (1) | DE68902209T2 (fi) |
DK (1) | DK491489A (fi) |
ES (1) | ES2052015T3 (fi) |
FI (1) | FI94632C (fi) |
GR (1) | GR3005779T3 (fi) |
HK (1) | HK143095A (fi) |
HU (1) | HU202211B (fi) |
IE (1) | IE61924B1 (fi) |
IL (1) | IL91704A0 (fi) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI91159C (fi) * | 1988-12-07 | 1994-05-25 | Tanabe Seiyaku Co | Menetelmä imidatsolipitoisten peptidien ja niiden farmaseuttisesti sopivien suolojen valmistamiseksi |
GB9020889D0 (en) * | 1990-09-25 | 1990-11-07 | May & Baker Ltd | New compositions of matter |
JP2564380Y2 (ja) * | 1993-12-10 | 1998-03-09 | 大阪瓦斯株式会社 | 締付トルク確認継手 |
DE19540027A1 (de) * | 1995-10-27 | 1997-04-30 | Gruenenthal Gmbh | Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe |
KR100426204B1 (ko) * | 1998-05-23 | 2004-06-24 | 문승자 | 합성수지판제조방법 |
US6365616B1 (en) | 1998-08-31 | 2002-04-02 | Sentron Medical, Inc. | Methimazole derivatives and tautomeric cyclic thiones to treat autoimmune diseases |
US20020142974A1 (en) * | 1998-09-11 | 2002-10-03 | Leonard D. Kohn | Immune activation by double-stranded polynucleotides |
RU2312101C2 (ru) | 2001-12-18 | 2007-12-10 | Ф.Хоффманн-Ля Рош Аг | Цис-имидазолины в качестве ингибиторов mdm2 |
US7132421B2 (en) | 2003-06-17 | 2006-11-07 | Hoffmann-La Roche Inc. | CIS-imidazoles |
JP4643570B2 (ja) * | 2003-06-17 | 2011-03-02 | エフ.ホフマン−ラ ロシュ アーゲー | Mdm2インヒビターとしてのシス−イミダゾリン類 |
US7425638B2 (en) | 2003-06-17 | 2008-09-16 | Hoffmann-La Roche Inc. | Cis-imidazolines |
KR20080027969A (ko) | 2004-05-18 | 2008-03-28 | 에프. 호프만-라 로슈 아게 | 신규 cis-이미다졸린 |
US7893278B2 (en) | 2004-06-17 | 2011-02-22 | Hoffman-La Roche Inc. | CIS-imidazolines |
US20110104186A1 (en) | 2004-06-24 | 2011-05-05 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
BRPI0619236A2 (pt) | 2005-12-01 | 2011-09-20 | Hoffmann La Roche | derivados de 2,4,5-trifenil imidazolina, composição farmacêutica que os compreende, uso e processo para a sìntese dos mesmos |
KR101015073B1 (ko) | 2006-01-18 | 2011-02-16 | 에프. 호프만-라 로슈 아게 | Mdm2 억제제로서의시스-4,5-비아릴-2-헤테로시클릭-이미다졸린 |
US7625895B2 (en) | 2007-04-12 | 2009-12-01 | Hoffmann-Le Roche Inc. | Diphenyl-dihydro-imidazopyridinones |
US8252942B2 (en) * | 2007-10-09 | 2012-08-28 | Board Of Trustees Of Michigan State University | Substituted imidazoline compounds |
RU2487127C2 (ru) | 2007-10-09 | 2013-07-10 | Ф.Хоффманн-Ля Рош Аг | Хиральные цис-имидазолины |
MX367576B (es) * | 2014-01-29 | 2019-08-27 | Toray Industries | Agente terapéutico o profiláctico para esclerosis múltiple. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH44279A (fr) * | 1908-03-09 | 1909-07-16 | Anonima Per Frigorigeni E Moto | Appareil pour l'échange de chaleur entre des fluides sous pression |
NL296772A (fi) * | 1962-03-21 | |||
GB1047569A (en) * | 1962-10-31 | 1966-11-09 | Du Pont | Light-sensitive compositions |
US3707475A (en) * | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
DE2960506D1 (en) * | 1978-04-24 | 1981-10-29 | Dumex Ltd As | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them |
US4424229A (en) * | 1979-04-23 | 1984-01-03 | A/S Dumex (Dumex Ltd.) | Fluorine containing 2,4,5-triphenylimidazoles |
US4252887A (en) * | 1979-08-14 | 1981-02-24 | E. I. Du Pont De Nemours And Company | Dimers derived from unsymmetrical 2,4,5-triphenylimidazole compounds as photoinitiators |
DE3141063A1 (de) * | 1981-10-13 | 1983-04-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
GB8906198D0 (en) * | 1989-03-17 | 1989-05-04 | Ciba Geigy Ag | Compounds |
-
1988
- 1988-10-06 JP JP63253391A patent/JPH02101065A/ja active Granted
-
1989
- 1989-09-18 CA CA000611765A patent/CA1330997C/en not_active Expired - Fee Related
- 1989-09-18 IE IE297789A patent/IE61924B1/en not_active IP Right Cessation
- 1989-09-20 IL IL91704A patent/IL91704A0/xx unknown
- 1989-09-26 DE DE8989309768T patent/DE68902209T2/de not_active Expired - Lifetime
- 1989-09-26 AT AT89309768T patent/ATE78470T1/de not_active IP Right Cessation
- 1989-09-26 ES ES89309768T patent/ES2052015T3/es not_active Expired - Lifetime
- 1989-09-26 EP EP89309768A patent/EP0363061B1/en not_active Expired - Lifetime
- 1989-09-27 CN CN89107616A patent/CN1020096C/zh not_active Expired - Fee Related
- 1989-09-27 KR KR1019890013908A patent/KR960009570B1/ko not_active IP Right Cessation
- 1989-09-29 AU AU42368/89A patent/AU611827B2/en not_active Ceased
- 1989-10-04 US US07/417,199 patent/US5051441A/en not_active Expired - Fee Related
- 1989-10-04 FI FI894693A patent/FI94632C/fi not_active IP Right Cessation
- 1989-10-05 DK DK491489A patent/DK491489A/da not_active Application Discontinuation
- 1989-10-05 HU HU895226A patent/HU202211B/hu not_active IP Right Cessation
-
1992
- 1992-09-24 GR GR920402101T patent/GR3005779T3/el unknown
-
1995
- 1995-09-07 HK HK143095A patent/HK143095A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI94632B (fi) | 1995-06-30 |
KR960009570B1 (ko) | 1996-07-20 |
HU202211B (en) | 1991-02-28 |
DK491489D0 (da) | 1989-10-05 |
DE68902209D1 (de) | 1992-08-27 |
GR3005779T3 (fi) | 1993-06-07 |
ES2052015T3 (es) | 1994-07-01 |
DE68902209T2 (de) | 1992-12-10 |
JPH0581592B2 (fi) | 1993-11-15 |
FI94632C (fi) | 1995-10-10 |
US5051441A (en) | 1991-09-24 |
ATE78470T1 (de) | 1992-08-15 |
JPH02101065A (ja) | 1990-04-12 |
AU611827B2 (en) | 1991-06-20 |
AU4236889A (en) | 1990-04-12 |
FI894693A0 (fi) | 1989-10-04 |
HUT51601A (en) | 1990-05-28 |
KR900006296A (ko) | 1990-05-07 |
DK491489A (da) | 1990-04-07 |
CN1041760A (zh) | 1990-05-02 |
FI894693A (fi) | 1990-04-07 |
HU895226D0 (en) | 1990-01-28 |
IE892977L (en) | 1990-04-06 |
IE61924B1 (en) | 1994-11-30 |
EP0363061B1 (en) | 1992-07-22 |
EP0363061A1 (en) | 1990-04-11 |
HK143095A (en) | 1995-09-15 |
CA1330997C (en) | 1994-07-26 |
CN1020096C (zh) | 1993-03-17 |
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