IL90733A - Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type - Google Patents

Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type

Info

Publication number
IL90733A
IL90733A IL9073389A IL9073389A IL90733A IL 90733 A IL90733 A IL 90733A IL 9073389 A IL9073389 A IL 9073389A IL 9073389 A IL9073389 A IL 9073389A IL 90733 A IL90733 A IL 90733A
Authority
IL
Israel
Prior art keywords
quinoxaline
mmol
dihydroxy
water
acid
Prior art date
Application number
IL9073389A
Other languages
English (en)
Hebrew (he)
Other versions
IL90733A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL90733A0 publication Critical patent/IL90733A0/xx
Publication of IL90733A publication Critical patent/IL90733A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D517/00Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D517/02Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
    • C07D517/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Luminescent Compositions (AREA)
IL9073389A 1988-06-28 1989-06-23 Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type IL90733A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK356788A DK160941C (da) 1988-06-28 1988-06-28 Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Publications (2)

Publication Number Publication Date
IL90733A0 IL90733A0 (en) 1990-01-18
IL90733A true IL90733A (en) 1994-02-27

Family

ID=8124358

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9073389A IL90733A (en) 1988-06-28 1989-06-23 Pharmaceutical preparations containing 2,3-new dihydroxyquinoxals and certain new compounds of this type

Country Status (18)

Country Link
US (5) US4977155A (sv)
EP (1) EP0348872B1 (sv)
JP (1) JPH0248578A (sv)
KR (1) KR910000735A (sv)
AT (1) ATE95181T1 (sv)
AU (1) AU619863B2 (sv)
CA (1) CA1326670C (sv)
DE (1) DE68909513T2 (sv)
DK (1) DK160941C (sv)
ES (1) ES2059636T3 (sv)
FI (1) FI91259C (sv)
IE (1) IE64289B1 (sv)
IL (1) IL90733A (sv)
NO (1) NO169390C (sv)
NZ (1) NZ229730A (sv)
PH (1) PH27565A (sv)
PT (1) PT91010B (sv)
ZA (1) ZA894903B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5153195A (en) * 1988-12-22 1992-10-06 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
PT99864B (pt) 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
US5196421A (en) * 1991-06-05 1993-03-23 Eli Lilly And Company Excitatory amino acid receptor antagonists in methods for the use thereof
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
DK162491D0 (da) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocycliske forbindelser, deres fremstilling og farmaceutiske praeparater indeholdende forbindelserne
JP3301024B2 (ja) * 1992-06-22 2002-07-15 ザ・リージェンツ・オブ・ザ・ユニバーシテイ・オブ・カリフォルニア グリシンレセプター拮抗物質及びその用途
JPH08502483A (ja) 1992-10-13 1996-03-19 ワーナー−ランバート・コンパニー 新規なキノキサリンジオン誘導体、それらの製造および使用
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
US5631373A (en) 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5576323A (en) * 1993-12-03 1996-11-19 Eli Lilly And Company Excitatory amino acid receptor antagonists
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
US5476851A (en) * 1994-09-08 1995-12-19 Rhone-Poulenc Rorer Pharmaceuticals, Inc. Pyrazolo[3,4-g]quinoxaline compounds which inhibit PDGF receptor protein tyrosine kinase
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
KR20000036227A (ko) 1996-09-27 2000-06-26 토마스 씨. 서 날라다아제조성물, 글루탐산염 이상 치료법 및 동물내의 뉴우런활성법
WO1998032439A1 (en) 1997-01-23 1998-07-30 Smithkline Beecham Corporation Il-8 receptor antagonists
FR2760237B1 (fr) * 1997-02-28 1999-04-16 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
US6288075B1 (en) 1998-02-26 2001-09-11 Rhone-Poulenc Rorer S.A. Thiazolo[5,4,3-ij]quinolines, preparation and medicines containing the same
FR2766487B1 (fr) * 1997-07-28 1999-08-27 Rhone Poulenc Rorer Sa Thiazolobenzoheterocycles, leur preparation et les medicaments les contenant
WO1999046267A1 (en) * 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
US6262044B1 (en) 1998-03-12 2001-07-17 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (PTPASES)
WO2009133778A1 (ja) * 2008-04-30 2009-11-05 住友化学株式会社 tert-ブチル 3-アミノピペリジン-1-カルボキシレートの製造方法およびその中間体
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
CN113549087A (zh) * 2020-04-26 2021-10-26 北京鼎材科技有限公司 一种化合物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1246578A (en) * 1982-03-29 1988-12-13 John H. Musser 2-oxo-1,3-oxazolo[4,5]quinolines useful as anti-allergy agents
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
DK356788D0 (da) 1988-06-28
KR910000735A (ko) 1991-01-30
IE64289B1 (en) 1995-07-26
JPH0248578A (ja) 1990-02-19
US5075306A (en) 1991-12-24
US4977155A (en) 1990-12-11
US5057516A (en) 1991-10-15
IL90733A0 (en) 1990-01-18
AU619863B2 (en) 1992-02-06
DE68909513D1 (de) 1993-11-04
NO169390C (no) 1992-06-17
FI91259B (sv) 1994-02-28
EP0348872A1 (en) 1990-01-03
NO892680D0 (no) 1989-06-27
IE892008L (en) 1989-12-28
NO892680L (no) 1989-12-29
DK160941C (da) 1991-10-21
FI893170A0 (sv) 1989-06-28
ATE95181T1 (de) 1993-10-15
ES2059636T3 (es) 1994-11-16
FI893170A (sv) 1989-12-29
US5109001A (en) 1992-04-28
NZ229730A (en) 1991-07-26
EP0348872B1 (en) 1993-09-29
DE68909513T2 (de) 1994-01-20
DK160941B (da) 1991-05-06
PT91010A (pt) 1989-12-29
FI91259C (sv) 1994-06-10
ZA894903B (en) 1990-03-28
PH27565A (en) 1993-08-18
DK356788A (da) 1990-03-21
US5079250A (en) 1992-01-07
NO169390B (no) 1992-03-09
CA1326670C (en) 1994-02-01
AU3707789A (en) 1990-01-04
PT91010B (pt) 1995-01-31

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Legal Events

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