IL90269A - A method for separating antibiotic substances from pharmaceutically acceptable mother and salt solutions - Google Patents

A method for separating antibiotic substances from pharmaceutically acceptable mother and salt solutions

Info

Publication number
IL90269A
IL90269A IL9026989A IL9026989A IL90269A IL 90269 A IL90269 A IL 90269A IL 9026989 A IL9026989 A IL 9026989A IL 9026989 A IL9026989 A IL 9026989A IL 90269 A IL90269 A IL 90269A
Authority
IL
Israel
Prior art keywords
chloro
cephem
dethia
carba
carboxylic acid
Prior art date
Application number
IL9026989A
Other languages
English (en)
Hebrew (he)
Other versions
IL90269A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL90269A0 publication Critical patent/IL90269A0/xx
Publication of IL90269A publication Critical patent/IL90269A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02Preparation
    • C07D463/06Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL9026989A 1988-05-13 1989-05-11 A method for separating antibiotic substances from pharmaceutically acceptable mother and salt solutions IL90269A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19347488A 1988-05-13 1988-05-13

Publications (2)

Publication Number Publication Date
IL90269A0 IL90269A0 (en) 1989-12-15
IL90269A true IL90269A (en) 1994-02-27

Family

ID=22713792

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9026989A IL90269A (en) 1988-05-13 1989-05-11 A method for separating antibiotic substances from pharmaceutically acceptable mother and salt solutions

Country Status (5)

Country Link
EP (1) EP0341991A3 (ko)
JP (1) JPH0215078A (ko)
KR (1) KR0135979B1 (ko)
HU (1) HU203761B (ko)
IL (1) IL90269A (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434259A (en) * 1993-02-05 1995-07-18 Eli Lilly And Company Process for isolation of cefaclor after enzymatic acylation
US5412094A (en) * 1993-06-28 1995-05-02 Eli Lilly And Company Bicyclic beta-lactam/paraben complexes
US6001996A (en) * 1995-05-11 1999-12-14 Eli Lilly And Company Complexes of cephalosporins and carbacephalosporins with parabens
US6362410B1 (en) 1999-09-28 2002-03-26 Kabushiki Kaisha Kawai Gakki Seisakusho Electronic musical instrument

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3676434A (en) * 1970-07-29 1972-07-11 Lilly Co Eli Cephalosporin salts
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
JPS608296A (ja) * 1983-06-29 1985-01-17 ユング・ジン・フア−マシウテイカル・インダストリアル・カンパニイ・リミテツド セフアロスポリン誘導体の製造方法
US4708956A (en) * 1985-12-12 1987-11-24 Kyowa Hakko Kogyo Co., Ltd. 3-position halogenated cephalosporin analogs and pharmaceutical compositions

Also Published As

Publication number Publication date
HU203761B (en) 1991-09-30
IL90269A0 (en) 1989-12-15
KR890017259A (ko) 1989-12-15
JPH0215078A (ja) 1990-01-18
EP0341991A3 (en) 1991-08-28
EP0341991A2 (en) 1989-11-15
KR0135979B1 (ko) 1998-04-25
HUT50350A (en) 1990-01-29

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Legal Events

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