IL87894A - Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them - Google Patents

Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL87894A
IL87894A IL8789488A IL8789488A IL87894A IL 87894 A IL87894 A IL 87894A IL 8789488 A IL8789488 A IL 8789488A IL 8789488 A IL8789488 A IL 8789488A IL 87894 A IL87894 A IL 87894A
Authority
IL
Israel
Prior art keywords
group
androstane
carboxylic acid
methyl
hydroxy
Prior art date
Application number
IL8789488A
Other languages
English (en)
Hebrew (he)
Other versions
IL87894A0 (en
Original Assignee
Norwich Eaton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Eaton Pharma filed Critical Norwich Eaton Pharma
Publication of IL87894A0 publication Critical patent/IL87894A0/xx
Publication of IL87894A publication Critical patent/IL87894A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Cephalosporin Compounds (AREA)
IL8789488A 1987-10-02 1988-09-30 Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them IL87894A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8713658A FR2621316B1 (fr) 1987-10-02 1987-10-02 Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant

Publications (2)

Publication Number Publication Date
IL87894A0 IL87894A0 (en) 1989-03-31
IL87894A true IL87894A (en) 1994-02-27

Family

ID=9355472

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8789488A IL87894A (en) 1987-10-02 1988-09-30 Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them

Country Status (22)

Country Link
US (1) US4885280A (xx)
EP (1) EP0310519B1 (xx)
JP (1) JP2783560B2 (xx)
KR (1) KR970002642B1 (xx)
AT (1) ATE79630T1 (xx)
AU (1) AU607100B2 (xx)
CA (1) CA1306248C (xx)
DE (1) DE3873870T2 (xx)
DK (1) DK165595C (xx)
EG (1) EG19114A (xx)
ES (1) ES2052761T3 (xx)
FI (1) FI89055C (xx)
FR (1) FR2621316B1 (xx)
GR (1) GR3005968T3 (xx)
HK (1) HK60297A (xx)
IE (1) IE61941B1 (xx)
IL (1) IL87894A (xx)
MY (1) MY103635A (xx)
NO (1) NO173011C (xx)
NZ (1) NZ226433A (xx)
PT (1) PT88648B (xx)
ZA (1) ZA887396B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252319A (en) * 1990-06-12 1993-10-12 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5209926A (en) * 1990-06-12 1993-05-11 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5256408A (en) * 1990-06-12 1993-10-26 Insite Vision Incorporated Aminosteroids for ophthalmic use
AU2675092A (en) * 1991-09-27 1993-04-27 Procter & Gamble Pharmaceuticals, Inc. Use of 14-aminosteroids for the manufacture of a medicament to slow the rate of progression of myocardial structural damages characteristic of congestive heart failure
AU4226593A (en) * 1992-06-26 1994-01-24 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
DE69424794D1 (de) * 1993-09-24 2000-07-06 Procter & Gamble Neue oligosaccharid-enthaltende 14-aminosteroidverbindungen und neuer diastereoselektive aminosteroid verfahren chemie
US5922703A (en) * 1993-09-24 1999-07-13 The Procter & Gamble Company Urethane-containing aminosteroid compounds
CA2172497A1 (en) * 1993-09-24 1995-03-30 Song Liu Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds
AU700131B2 (en) * 1993-09-24 1998-12-24 Procter & Gamble Company, The Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds
BR9709835A (pt) * 1996-06-17 1999-08-10 Procter & Gamble Compostos 14-aminoesteróides contendo açúcar substituído com deóxi e oxigênio para uso como um antiarrítmico
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法
GB201112402D0 (en) 2011-07-19 2011-08-31 British American Tobacco Co Cellulose acetate compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449381A (en) * 1962-06-12 1969-06-10 Syntex Corp 19-oxo- and 19-lower alkyl-19-oxoandrostane derivatives
US3634409A (en) * 1966-04-26 1972-01-11 Syntex Corp 3beta-tetrahydrofuran-2'-yloxy-delta**4-steroids of the androstane and estrane series
FR2464270A1 (fr) * 1979-08-31 1981-03-06 Nativelle Sa Ets Nouveaux derives d'amino-14 steroides, et procede pour leur preparation
ES524796A0 (es) * 1982-08-20 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos derivos de amino-14 esteroides
NZ205293A (en) * 1982-08-20 1986-12-05 Nativelle Sa Ets 14-aminosteroids and pharmaceutical compositions

Also Published As

Publication number Publication date
NO884344D0 (no) 1988-09-30
EP0310519A1 (fr) 1989-04-05
KR970002642B1 (ko) 1997-03-07
NZ226433A (en) 1991-06-25
ES2052761T3 (es) 1994-07-16
DK549388D0 (da) 1988-09-30
FR2621316B1 (fr) 1991-06-21
JPH01156995A (ja) 1989-06-20
HK60297A (en) 1997-05-16
ZA887396B (en) 1991-11-27
IL87894A0 (en) 1989-03-31
IE882991L (en) 1989-04-02
DK165595B (da) 1992-12-21
FI89055B (fi) 1993-04-30
CA1306248C (en) 1992-08-11
DK549388A (da) 1989-04-03
ATE79630T1 (de) 1992-09-15
MY103635A (en) 1993-08-28
EP0310519B1 (fr) 1992-08-19
FI884511A (fi) 1989-04-03
JP2783560B2 (ja) 1998-08-06
PT88648B (pt) 1992-12-31
DK165595C (da) 1993-05-03
NO884344L (no) 1989-04-03
AU2293588A (en) 1989-04-06
EG19114A (fr) 1994-07-30
KR890006667A (ko) 1989-06-15
US4885280A (en) 1989-12-05
FI89055C (fi) 1993-08-10
PT88648A (pt) 1988-10-01
AU607100B2 (en) 1991-02-21
FI884511A0 (fi) 1988-09-30
FR2621316A1 (fr) 1989-04-07
NO173011B (no) 1993-07-05
DE3873870D1 (de) 1992-09-24
NO173011C (no) 1993-10-13
DE3873870T2 (de) 1993-02-18
IE61941B1 (en) 1994-11-30
GR3005968T3 (xx) 1993-06-07

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Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void
RH1 Patent not in force