IL87018A - Pharmaceutical compositions containing 2-(heterocyclylalkyl) -imidazopyridines, some such novel compounds and their preparation - Google Patents

Pharmaceutical compositions containing 2-(heterocyclylalkyl) -imidazopyridines, some such novel compounds and their preparation

Info

Publication number
IL87018A
IL87018A IL87018A IL8701888A IL87018A IL 87018 A IL87018 A IL 87018A IL 87018 A IL87018 A IL 87018A IL 8701888 A IL8701888 A IL 8701888A IL 87018 A IL87018 A IL 87018A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
alk
formula
imidazopyridines
heterocyclylalkyl
Prior art date
Application number
IL87018A
Other languages
English (en)
Other versions
IL87018A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL87018A0 publication Critical patent/IL87018A0/xx
Publication of IL87018A publication Critical patent/IL87018A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL87018A 1987-07-10 1988-07-06 Pharmaceutical compositions containing 2-(heterocyclylalkyl) -imidazopyridines, some such novel compounds and their preparation IL87018A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878716313A GB8716313D0 (en) 1987-07-10 1987-07-10 2-(heterocyclylalkyl)imidazopyridines

Publications (2)

Publication Number Publication Date
IL87018A0 IL87018A0 (en) 1988-12-30
IL87018A true IL87018A (en) 1993-02-21

Family

ID=10620462

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87018A IL87018A (en) 1987-07-10 1988-07-06 Pharmaceutical compositions containing 2-(heterocyclylalkyl) -imidazopyridines, some such novel compounds and their preparation

Country Status (21)

Country Link
US (3) US4946843A (pt)
EP (1) EP0307014B1 (pt)
JP (1) JPS6431782A (pt)
KR (1) KR890001547A (pt)
CN (1) CN1020906C (pt)
AT (1) ATE83147T1 (pt)
AU (1) AU608336B2 (pt)
CA (1) CA1324131C (pt)
DE (1) DE3876551T2 (pt)
DK (1) DK382388A (pt)
ES (1) ES2042711T3 (pt)
FI (1) FI89483C (pt)
GB (1) GB8716313D0 (pt)
GR (1) GR3006971T3 (pt)
HU (1) HU204827B (pt)
IE (1) IE61354B1 (pt)
IL (1) IL87018A (pt)
NO (1) NO167979C (pt)
NZ (1) NZ225151A (pt)
PT (1) PT87939B (pt)
ZA (1) ZA884946B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
IT1229231B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Aminoimidazopiridine farmacologicamente attive
DE3915025A1 (de) * 1989-05-08 1990-11-15 Dompe Farmaceutici Spa 2-substituierte 3-(2'aethoxy)-aethyl)-imidazo(4,5-b)pyridinderivate und diese enthaltende arzneimittel
FR2665160A1 (fr) * 1990-07-26 1992-01-31 Esteve Labor Dr Nouveaux derives de 1-diphenylmethylpiperazine, leur preparation et leur application en tant que medicaments.
AU3258293A (en) * 1992-01-09 1993-08-03 Janssen Pharmaceutica N.V. Antihistaminic piperazinyl derivatives
EP0556889A1 (en) * 1992-02-18 1993-08-25 Duphar International Research B.V Method of preparing aryl(homo)piperazines
CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
US5670506A (en) * 1993-04-05 1997-09-23 Cell Therapeutics, Inc. Halogen, isothiocyanate or azide substituted xanthines
US6020337A (en) * 1993-04-05 2000-02-01 Cell Therapeutics, Inc. Electronegative-substituted long chain xanthine compounds
IL125658A0 (en) * 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
US6339087B1 (en) * 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
CZ20014573A3 (cs) 1999-06-28 2002-05-15 Janssen Pharmaceutica N. V. Inhibitory replikace respiračně syncyciálního viru
ES2215683T3 (es) * 1999-06-28 2004-10-16 Janssen Pharmaceutica N.V. Inhibidores de la replicacion del virus sincitial respiratorio.
EP1418175A1 (en) * 1999-06-28 2004-05-12 Janssen Pharmaceutica N.V. Respiratory syncytial virus replication inhibitors
US6559140B2 (en) * 2000-03-09 2003-05-06 Abbott Laboratories Cyclic and bicyclic diamino histamine-3 receptor antagonists
JP2001353678A (ja) * 2000-06-12 2001-12-25 Sony Corp オーサリング・システム及びオーサリング方法、並びに記憶媒体
GB0015381D0 (en) * 2000-06-26 2000-08-16 Acma Ltd Particulate metal oxide
US6906190B2 (en) * 2002-01-04 2005-06-14 Ribapharm Inc. Inhibitors for de novo-RNA polymerases and methods of identifying targets for same
JP2005532991A (ja) * 2002-01-10 2005-11-04 ニューロジェン・コーポレーション メラニン凝集ホルモン受容体リガンド：置換２−（４−ベンジル−ピペラジン−１−イルメチル）−及び２−（４−ベンジル−ジアゼパン−１−イルメチル）−１ｈ−ベンゾイミダゾールアナログ
AU2003284142A1 (en) * 2002-10-15 2004-05-04 Synta Pharmaceuticals Corp Aromatic bicyclic heterocyles to modulate 1L-12 production
WO2005046698A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
DE10359839A1 (de) * 2003-12-19 2005-07-21 Sachtleben Chemie Gmbh Verfahren zur Herstellung einer Katalysatorpräparation und Verwendung der Katalysatorpräparation
US7705150B2 (en) * 2004-02-04 2010-04-27 Biosearch Technologies, Inc. Cyanine dyes
BRPI0807799B8 (pt) * 2007-01-25 2021-05-25 Janssen Pharmaceutica Nv derivados de 2-piperazin-1-il-3h-imidazo[4,5-b]piridina, composição farmacêutica que os compreende, seu processo de preparação e uso
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1620450C3 (de) * 1964-07-23 1976-01-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen 1 - (2- Hydroxybenzyl) -2-piperazinomethylbenzimidazole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
FR2531085A1 (fr) * 1982-07-28 1984-02-03 Adir Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant
JPS59199679A (ja) * 1983-04-27 1984-11-12 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
GB8515934D0 (en) * 1985-06-24 1985-07-24 Janssen Pharmaceutica Nv (4-piperidinomethyl and-hetero)purines
US4897401A (en) * 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
NZ225447A (en) * 1987-07-20 1991-12-23 Merck & Co Inc Piperazinyl derivatives of purine and purine isosteres and pharmaceutical compositions

Also Published As

Publication number Publication date
AU608336B2 (en) 1991-03-28
ES2042711T3 (es) 1993-12-16
NO167979B (no) 1991-09-23
CA1324131C (en) 1993-11-09
IE882105L (en) 1989-01-10
AU1885388A (en) 1989-01-12
HU204827B (en) 1992-02-28
IE61354B1 (en) 1994-11-02
US5011842A (en) 1991-04-30
JPS6431782A (en) 1989-02-02
DE3876551T2 (de) 1993-04-15
CN1030587A (zh) 1989-01-25
NO167979C (no) 1992-01-02
PT87939A (pt) 1989-06-30
EP0307014B1 (en) 1992-12-09
ZA884946B (en) 1990-03-28
NO883069L (no) 1989-01-11
CN1020906C (zh) 1993-05-26
EP0307014A1 (en) 1989-03-15
FI883282A0 (fi) 1988-07-08
US4946843A (en) 1990-08-07
NO883069D0 (no) 1988-07-08
PT87939B (pt) 1995-03-01
GB8716313D0 (en) 1987-08-19
DK382388A (da) 1989-01-11
FI89483C (fi) 1993-10-11
HUT47573A (en) 1989-03-28
FI883282A7 (fi) 1989-01-11
KR890001547A (ko) 1989-03-27
DK382388D0 (da) 1988-07-08
NZ225151A (en) 1990-04-26
DE3876551D1 (en) 1993-01-21
US5086056A (en) 1992-02-04
ATE83147T1 (de) 1992-12-15
GR3006971T3 (pt) 1993-06-30
FI89483B (fi) 1993-06-30
IL87018A0 (en) 1988-12-30

Similar Documents

Publication Publication Date Title
IL87018A (en) Pharmaceutical compositions containing 2-(heterocyclylalkyl) -imidazopyridines, some such novel compounds and their preparation
JPS6434979A (en) Pyrrolidine derivative and antiallergic composition
IL92729A0 (en) 2-aminopyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
IL94008A (en) Hydroxyalkylfuranyl derivatives their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
RH Patent void