IL86928A - Castanospermine esters and glycosides,their preparation and compositions containing them for treating diabetes and postprandial hyperglycemia - Google Patents

Castanospermine esters and glycosides,their preparation and compositions containing them for treating diabetes and postprandial hyperglycemia

Info

Publication number
IL86928A
IL86928A IL86928A IL8692888A IL86928A IL 86928 A IL86928 A IL 86928A IL 86928 A IL86928 A IL 86928A IL 8692888 A IL8692888 A IL 8692888A IL 86928 A IL86928 A IL 86928A
Authority
IL
Israel
Prior art keywords
glycosides
preparation
compositions containing
treating diabetes
postprandial hyperglycemia
Prior art date
Application number
IL86928A
Other languages
English (en)
Other versions
IL86928A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL86928A0 publication Critical patent/IL86928A0/xx
Publication of IL86928A publication Critical patent/IL86928A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL86928A 1987-07-02 1988-06-30 Castanospermine esters and glycosides,their preparation and compositions containing them for treating diabetes and postprandial hyperglycemia IL86928A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6935187A 1987-07-02 1987-07-02

Publications (2)

Publication Number Publication Date
IL86928A0 IL86928A0 (en) 1988-11-30
IL86928A true IL86928A (en) 1992-08-18

Family

ID=22088386

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86928A IL86928A (en) 1987-07-02 1988-06-30 Castanospermine esters and glycosides,their preparation and compositions containing them for treating diabetes and postprandial hyperglycemia

Country Status (20)

Country Link
EP (1) EP0297534B1 (es)
JP (1) JP2683915B2 (es)
KR (1) KR970002636B1 (es)
CN (2) CN1020609C (es)
AR (1) AR245128A1 (es)
AT (1) ATE116318T1 (es)
AU (1) AU609146B2 (es)
CA (1) CA1315276C (es)
DE (1) DE3852579T2 (es)
DK (1) DK171053B1 (es)
ES (1) ES2068816T3 (es)
FI (1) FI87072C (es)
GR (1) GR3015303T3 (es)
HU (1) HU199470B (es)
IE (1) IE65164B1 (es)
IL (1) IL86928A (es)
NO (1) NO167664C (es)
NZ (1) NZ225198A (es)
PT (1) PT87895B (es)
ZA (1) ZA884587B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis
US5214050A (en) * 1989-10-17 1993-05-25 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
AU628228B2 (en) * 1989-10-17 1992-09-10 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5066807A (en) * 1990-03-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine
US5028614A (en) * 1990-03-30 1991-07-02 Merrell Dow Pharmaceuticals Inc. Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
US5079254A (en) * 1990-06-04 1992-01-07 Merrell Dow Pharmaceuticals Inc. Derivatives of 6-aminooctahydroindolizinetriol
ES2212292T3 (es) * 1997-05-22 2004-07-16 Aventis Pharmaceuticals Inc. Procedimiento para preparar 6-0-monoesteres de castanospermina.
GB0110832D0 (en) 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
KR20070053229A (ko) * 2004-08-13 2007-05-23 미게닉스 인코포레이티드 헤파드나비리대 감염을 치료 또는 예방하기 위한 조성물 및방법
DE102020212985B3 (de) 2020-10-14 2021-10-21 Danfoss Power Solutions Gmbh & Co. Ohg Hydraulischer ventilblock sowie hydraulikeinheit für geschlossene kreislaufanwendungen

Also Published As

Publication number Publication date
FI87072C (fi) 1992-11-25
EP0297534B1 (en) 1994-12-28
NZ225198A (en) 1989-12-21
DE3852579D1 (de) 1995-02-09
IE65164B1 (en) 1995-10-04
FI87072B (fi) 1992-08-14
NO882940D0 (no) 1988-07-01
ATE116318T1 (de) 1995-01-15
HU199470B (en) 1990-02-28
KR890002147A (ko) 1989-04-08
ES2068816T3 (es) 1995-05-01
NO882940L (no) 1989-01-03
EP0297534A3 (en) 1990-01-10
FI883164A (fi) 1989-01-03
KR970002636B1 (ko) 1997-03-07
DK366888D0 (da) 1988-07-01
CN1020609C (zh) 1993-05-12
FI883164A0 (fi) 1988-07-01
JP2683915B2 (ja) 1997-12-03
CN1065066A (zh) 1992-10-07
GR3015303T3 (en) 1995-06-30
AU1844888A (en) 1989-01-05
JPS6479179A (en) 1989-03-24
DE3852579T2 (de) 1995-05-04
PT87895B (pt) 1995-03-01
CA1315276C (en) 1993-03-30
NO167664C (no) 1991-11-27
CN1030418A (zh) 1989-01-18
NO167664B (no) 1991-08-19
IL86928A0 (en) 1988-11-30
CN1027264C (zh) 1995-01-04
PT87895A (pt) 1989-06-30
EP0297534A2 (en) 1989-01-04
HUT47572A (en) 1989-03-28
AR245128A1 (es) 1993-12-30
AU609146B2 (en) 1991-04-26
DK366888A (da) 1989-01-03
IE882021L (en) 1989-01-02
ZA884587B (en) 1989-03-29
DK171053B1 (da) 1996-05-06

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.

MM9K Patent not in force due to non-payment of renewal fees