IL86232A - Cardiotonic 1,3-dihydro-2h-imidazo(4,5:1,2)cycloalkadieno(4,3-c)pyridin-2-(thi)ones,their preparation and pharmaceutical compositions containing them - Google Patents

Cardiotonic 1,3-dihydro-2h-imidazo(4,5:1,2)cycloalkadieno(4,3-c)pyridin-2-(thi)ones,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL86232A
IL86232A IL86232A IL8623288A IL86232A IL 86232 A IL86232 A IL 86232A IL 86232 A IL86232 A IL 86232A IL 8623288 A IL8623288 A IL 8623288A IL 86232 A IL86232 A IL 86232A
Authority
IL
Israel
Prior art keywords
cycloalkadieno
cardiotonic
thi
imidazo
pyridin
Prior art date
Application number
IL86232A
Other languages
English (en)
Other versions
IL86232A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL86232A0 publication Critical patent/IL86232A0/xx
Publication of IL86232A publication Critical patent/IL86232A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL86232A 1987-05-29 1988-04-29 Cardiotonic 1,3-dihydro-2h-imidazo(4,5:1,2)cycloalkadieno(4,3-c)pyridin-2-(thi)ones,their preparation and pharmaceutical compositions containing them IL86232A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/055,666 US4743607A (en) 1987-05-29 1987-05-29 Cardiotonic tricyclic imidazolones

Publications (2)

Publication Number Publication Date
IL86232A0 IL86232A0 (en) 1988-11-15
IL86232A true IL86232A (en) 1992-07-15

Family

ID=21999387

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86232A IL86232A (en) 1987-05-29 1988-04-29 Cardiotonic 1,3-dihydro-2h-imidazo(4,5:1,2)cycloalkadieno(4,3-c)pyridin-2-(thi)ones,their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4743607A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0292711B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2657819B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR970000044B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1017152B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR243524A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE73454T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU602468B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1329807C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3868978D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK253888A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2033361T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI88034C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3004049T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU198049B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL86232A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO167144C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ224352A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH24527A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT87441B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA883271B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4490543B2 (ja) * 2000-03-07 2010-06-30 日本曹達株式会社 α−アミノケトン類の製造方法
JP2008536844A (ja) * 2005-04-15 2008-09-11 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル ニューロトロフィン類似体を用いた細胞生存促進法
US20110230479A1 (en) * 2005-04-15 2011-09-22 Longo Frank M Neurotrophin mimetics and uses thereof
CN108383804A (zh) 2009-11-12 2018-08-10 特罗菲克斯制药股份有限公司 神经营养蛋白模拟化合物及其盐的晶型
US10273219B2 (en) 2009-11-12 2019-04-30 Pharmatrophix, Inc. Crystalline forms of neurotrophin mimetic compounds and their salts

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1106962B (it) * 1977-01-17 1985-11-18 Sumitomo Chemical Co Composit derivati del benzossa tiazolone utilizzabili particolarmente come fungicidi
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US4668686A (en) * 1985-04-25 1987-05-26 Bristol-Myers Company Imidazoquinoline antithrombrogenic cardiotonic agents
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
DE3868978D1 (de) 1992-04-16
US4743607A (en) 1988-05-10
HUT47108A (en) 1989-01-30
FI88034B (fi) 1992-12-15
EP0292711A1 (en) 1988-11-30
CN1017152B (zh) 1992-06-24
GR3004049T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-03-31
EP0292711B1 (en) 1992-03-11
AU602468B2 (en) 1990-10-11
ES2033361T3 (es) 1993-03-16
NO882028D0 (no) 1988-05-09
ZA883271B (en) 1988-12-28
IL86232A0 (en) 1988-11-15
NZ224352A (en) 1990-02-26
AR243524A1 (es) 1993-08-31
NO167144B (no) 1991-07-01
KR970000044B1 (en) 1997-01-04
JP2657819B2 (ja) 1997-09-30
PH24527A (en) 1990-07-18
NO882028L (no) 1988-11-30
FI882159L (fi) 1988-11-30
FI88034C (fi) 1993-03-25
PT87441B (pt) 1992-08-31
NO167144C (no) 1991-10-09
DK253888A (da) 1988-11-30
CN1030417A (zh) 1989-01-18
JPS63307877A (ja) 1988-12-15
PT87441A (pt) 1989-05-31
FI882159A0 (fi) 1988-05-09
DK253888D0 (da) 1988-05-09
HU198049B (en) 1989-07-28
ATE73454T1 (de) 1992-03-15
CA1329807C (en) 1994-05-24
AU1582188A (en) 1988-12-01
KR880013936A (ko) 1988-12-22

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.