ATE73454T1 - Cardiotonische tricyclische imidazolone. - Google Patents

Cardiotonische tricyclische imidazolone.

Info

Publication number
ATE73454T1
ATE73454T1 AT88106634T AT88106634T ATE73454T1 AT E73454 T1 ATE73454 T1 AT E73454T1 AT 88106634 T AT88106634 T AT 88106634T AT 88106634 T AT88106634 T AT 88106634T AT E73454 T1 ATE73454 T1 AT E73454T1
Authority
AT
Austria
Prior art keywords
imidazolones
cardiotonic
tricyclic
tricyclic imidazolones
cardiotonic tricyclic
Prior art date
Application number
AT88106634T
Other languages
English (en)
Inventor
Winton D Jones
George P Claxton
Richard A Schnettler
Richard C Dage
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE73454T1 publication Critical patent/ATE73454T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT88106634T 1987-05-29 1988-04-26 Cardiotonische tricyclische imidazolone. ATE73454T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/055,666 US4743607A (en) 1987-05-29 1987-05-29 Cardiotonic tricyclic imidazolones
EP88106634A EP0292711B1 (de) 1987-05-29 1988-04-26 Cardiotonische tricyclische Imidazolone

Publications (1)

Publication Number Publication Date
ATE73454T1 true ATE73454T1 (de) 1992-03-15

Family

ID=21999387

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88106634T ATE73454T1 (de) 1987-05-29 1988-04-26 Cardiotonische tricyclische imidazolone.

Country Status (21)

Country Link
US (1) US4743607A (de)
EP (1) EP0292711B1 (de)
JP (1) JP2657819B2 (de)
KR (1) KR970000044B1 (de)
CN (1) CN1017152B (de)
AR (1) AR243524A1 (de)
AT (1) ATE73454T1 (de)
AU (1) AU602468B2 (de)
CA (1) CA1329807C (de)
DE (1) DE3868978D1 (de)
DK (1) DK253888A (de)
ES (1) ES2033361T3 (de)
FI (1) FI88034C (de)
GR (1) GR3004049T3 (de)
HU (1) HU198049B (de)
IL (1) IL86232A (de)
NO (1) NO167144C (de)
NZ (1) NZ224352A (de)
PH (1) PH24527A (de)
PT (1) PT87441B (de)
ZA (1) ZA883271B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4490543B2 (ja) * 2000-03-07 2010-06-30 日本曹達株式会社 α−アミノケトン類の製造方法
WO2006113097A2 (en) * 2005-04-15 2006-10-26 The University Of North Carolina At Chapel Hill Methods of facilitating cell survival using neurotrophin mimetics
US20110230479A1 (en) * 2005-04-15 2011-09-22 Longo Frank M Neurotrophin mimetics and uses thereof
EP3470402B1 (de) 2009-11-12 2021-01-06 Pharmatrophix Inc. Kristalline formen aus neurotrophinmimetischen verbindungen und deren salzen
US10273219B2 (en) 2009-11-12 2019-04-30 Pharmatrophix, Inc. Crystalline forms of neurotrophin mimetic compounds and their salts

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1106962B (it) * 1977-01-17 1985-11-18 Sumitomo Chemical Co Composit derivati del benzossa tiazolone utilizzabili particolarmente come fungicidi
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity
JPS61215389A (ja) * 1985-03-20 1986-09-25 Kyowa Hakko Kogyo Co Ltd キナゾリン誘導体およびそれを含有する強心剤
US4668686A (en) * 1985-04-25 1987-05-26 Bristol-Myers Company Imidazoquinoline antithrombrogenic cardiotonic agents
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
NO882028L (no) 1988-11-30
FI88034C (fi) 1993-03-25
JP2657819B2 (ja) 1997-09-30
EP0292711A1 (de) 1988-11-30
KR880013936A (ko) 1988-12-22
DK253888A (da) 1988-11-30
HUT47108A (en) 1989-01-30
PT87441A (pt) 1989-05-31
EP0292711B1 (de) 1992-03-11
AR243524A1 (es) 1993-08-31
NO167144B (no) 1991-07-01
FI882159A (fi) 1988-11-30
PT87441B (pt) 1992-08-31
DK253888D0 (da) 1988-05-09
NZ224352A (en) 1990-02-26
NO882028D0 (no) 1988-05-09
FI882159A0 (fi) 1988-05-09
HU198049B (en) 1989-07-28
DE3868978D1 (de) 1992-04-16
AU1582188A (en) 1988-12-01
CN1030417A (zh) 1989-01-18
FI88034B (fi) 1992-12-15
GR3004049T3 (de) 1993-03-31
ES2033361T3 (es) 1993-03-16
IL86232A0 (en) 1988-11-15
ZA883271B (en) 1988-12-28
AU602468B2 (en) 1990-10-11
CA1329807C (en) 1994-05-24
PH24527A (en) 1990-07-18
CN1017152B (zh) 1992-06-24
IL86232A (en) 1992-07-15
NO167144C (no) 1991-10-09
JPS63307877A (ja) 1988-12-15
US4743607A (en) 1988-05-10
KR970000044B1 (en) 1997-01-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee