IL85119A - Streptomyces avermitilis strains, their preparation and use in production of avermectins - Google Patents

Streptomyces avermitilis strains, their preparation and use in production of avermectins

Info

Publication number
IL85119A
IL85119A IL85119A IL8511988A IL85119A IL 85119 A IL85119 A IL 85119A IL 85119 A IL85119 A IL 85119A IL 8511988 A IL8511988 A IL 8511988A IL 85119 A IL85119 A IL 85119A
Authority
IL
Israel
Prior art keywords
avermectins
preparation
production
streptomyces avermitilis
avermitilis strains
Prior art date
Application number
IL85119A
Other languages
English (en)
Other versions
IL85119A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL85119A0 publication Critical patent/IL85119A0/xx
Publication of IL85119A publication Critical patent/IL85119A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL85119A 1987-01-23 1988-01-18 Streptomyces avermitilis strains, their preparation and use in production of avermectins IL85119A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US651287A 1987-01-23 1987-01-23
US10782587A 1987-10-13 1987-10-13

Publications (2)

Publication Number Publication Date
IL85119A0 IL85119A0 (en) 1988-06-30
IL85119A true IL85119A (en) 1993-01-14

Family

ID=26675723

Family Applications (1)

Application Number Title Priority Date Filing Date
IL85119A IL85119A (en) 1987-01-23 1988-01-18 Streptomyces avermitilis strains, their preparation and use in production of avermectins

Country Status (26)

Country Link
EP (1) EP0284176B1 (es)
JP (1) JPH0817694B2 (es)
KR (1) KR900007937B1 (es)
CN (1) CN1065277C (es)
AP (1) AP53A (es)
AR (1) AR244344A1 (es)
AU (1) AU636709B2 (es)
BG (1) BG48572A3 (es)
CA (1) CA1338141C (es)
CZ (1) CZ290312B6 (es)
DE (1) DE3883408T2 (es)
DK (1) DK175724B1 (es)
EG (1) EG18796A (es)
ES (1) ES2058244T3 (es)
FI (1) FI90087C (es)
HU (1) HU203130B (es)
IE (1) IE62467B1 (es)
IL (1) IL85119A (es)
MA (1) MA21161A1 (es)
MX (1) MX169293B (es)
MY (1) MY102581A (es)
NO (2) NO172446C (es)
NZ (1) NZ223270A (es)
PT (1) PT86582B (es)
RU (1) RU2096462C1 (es)
YU (2) YU47877B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE89604T1 (de) * 1987-10-23 1993-06-15 Pfizer Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
GB8807280D0 (en) * 1988-03-26 1988-04-27 Pfizer Ltd Antiparasitic agents
GB8809232D0 (en) * 1988-04-19 1988-05-25 Pfizer Ltd Antiparasitic agents
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
US5030622A (en) * 1989-06-02 1991-07-09 Merck & Co., Inc. Avermectin derivatives
US5057499A (en) * 1989-06-02 1991-10-15 Merck & Co. Inc. Avermectin derivatives
NZ238521A (en) * 1990-06-22 1992-12-23 Merck & Co Inc Process for the conversion of avermectin glycone to avermectin mono- and disaccharides by fermentation with streptomyces avermitilis ma6078
NZ240128A (en) * 1990-10-15 1994-01-26 Merck & Co Inc Production of 13-beta and 5-beta ivermectin monoglucopyranosides from
US5250422A (en) * 1990-10-15 1993-10-05 Merck & Co., Inc. Biotransformation process for the production of invermectin derivatives
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
US5292647A (en) * 1992-11-30 1994-03-08 Eli Lilly And Company Strain of streptomyces for producing avermectins and processes therewith
CN1038330C (zh) * 1993-07-05 1998-05-13 塞泰克斯公司 阿弗麦菌素的生产与分离
CA2167520C (en) * 1993-07-30 1999-07-27 Claudio D. Denoya Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis
US5466102A (en) 1993-12-16 1995-11-14 Kennametal Inc. System for coupling machine tools
GB9716567D0 (en) * 1997-08-05 1997-10-08 Pfizer Process
GB9825402D0 (en) 1998-11-19 1999-01-13 Pfizer Ltd Antiparasitic formulations
KR20040045440A (ko) 2001-09-17 2004-06-01 일라이 릴리 앤드 캄파니 농약 배합물
CN101560535B (zh) * 2009-05-26 2012-05-23 浙江升华拜克生物股份有限公司 一种基于代谢参数our补糖发酵生产阿维菌素工艺
WO2011048040A1 (en) 2009-10-19 2011-04-28 Intervet International B.V. Method and formulation for the control of parasites
RU2454420C1 (ru) * 2011-03-31 2012-06-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Цитотоксические полусинтетические производные макролидного антибиотика олигомицина а и способ их получения
CN104877925B (zh) * 2014-02-28 2018-05-25 中国科学院沈阳应用生态研究所 一种异壁放线菌和三种新的抗真菌maclafungins类化合物及其制备和应用
CN116602242B (zh) * 2023-05-08 2024-01-23 中国水产科学研究院珠江水产研究所 一种提高反季鱼苗成活率的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4429042A (en) * 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
NZ204074A (en) * 1982-05-10 1986-05-09 Merck & Co Inc Synergistic compositions containing avermectins
NZ207655A (en) * 1983-04-07 1986-09-10 Merck & Co Inc Synergistic veterinary compositions containing an avermectin compound and clorsulon
NZ210505A (en) * 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
EP0240274A3 (en) * 1986-04-03 1990-03-14 Merck & Co. Inc. Avermectins as growth promotant agents

Also Published As

Publication number Publication date
IE62467B1 (en) 1995-02-08
AU636709B2 (en) 1993-05-06
YU47886B (sh) 1996-05-20
AU1069788A (en) 1988-07-28
HUT48684A (en) 1989-06-28
CZ290312B6 (cs) 2002-07-17
MX169293B (es) 1993-06-28
DE3883408D1 (de) 1993-09-30
FI880279A0 (fi) 1988-01-22
EP0284176A2 (en) 1988-09-28
JPS6419093A (en) 1989-01-23
JPH0817694B2 (ja) 1996-02-28
EP0284176B1 (en) 1993-08-25
AP53A (en) 1989-09-17
AP8800077A0 (en) 1987-11-01
HU203130B (en) 1991-05-28
YU99090A (sh) 1992-07-20
DE3883408T2 (de) 1993-12-09
MA21161A1 (fr) 1988-10-01
DK28688D0 (da) 1988-01-22
CA1338141C (en) 1996-03-12
EP0284176A3 (en) 1989-11-02
AU7111391A (en) 1991-10-03
EG18796A (en) 1994-09-29
NO172446C (no) 1993-07-21
NO172447C (no) 1993-07-21
KR880009121A (ko) 1988-09-14
NO880261L (no) 1988-07-25
IE880159L (en) 1988-07-23
ES2058244T3 (es) 1994-11-01
RU2096462C1 (ru) 1997-11-20
IL85119A0 (en) 1988-06-30
YU10988A (en) 1990-02-28
NO880262D0 (no) 1988-01-22
YU47877B (sh) 1996-05-20
BG48572A3 (en) 1991-03-15
NO172446B (no) 1993-04-13
AU603415B2 (en) 1990-11-15
NO880261D0 (no) 1988-01-22
PT86582A (en) 1988-02-01
NO172447B (no) 1993-04-13
FI880279A (fi) 1988-07-24
CZ40888A3 (cs) 2000-08-16
CN88100373A (zh) 1988-08-31
DK175724B1 (da) 2005-02-07
MY102581A (en) 1992-07-31
PT86582B (pt) 1991-12-31
CN1065277C (zh) 2001-05-02
AR244344A1 (es) 1993-10-29
FI90087C (fi) 1993-12-27
NZ223270A (en) 1991-12-23
FI90087B (fi) 1993-09-15
NO880262L (no) 1988-07-25
DK28688A (da) 1988-07-24
KR900007937B1 (ko) 1990-10-23

Similar Documents

Publication Publication Date Title
IL85119A (en) Streptomyces avermitilis strains, their preparation and use in production of avermectins
IL85165A0 (en) Streptomyces mutant strains and their use for production of b avermectins
DE3574019D1 (en) Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
CY1719A (en) Antiparasitic avermectin and milbemycin derivatives and process for the preparation
IL87290A0 (en) Epipodophyllotoxin glucoside 4'-phosphate derivatives,their preparation and pharmaceutical compositions containing them
IL88182A0 (en) Derivatives of 1-desoxynojirimicyin and 1-desoxymannonojirimycin,their preparation and their use in medicaments
AU7060787A (en) Macrolide compounds their preparation and their use
EP0299370A3 (en) Sulphatizated hydroxy-mixed ethers, process for their preparation and their use
AU1466388A (en) Low molecular weight heparins of regular structure, their preparation and their biological uses
AU2740188A (en) N6-hydroxycycloalkyl and N6-hydroxycycloakenyl adenosine derivatives
JPS6468378A (en) Novel avermectin derivative, its production and use
IL85598A (en) Soluble polyimidesiloxanes,their preparation and products made therefrom
AU2369484A (en) Avermectin and milbemycin phosphate esters
AU605218B2 (en) 26-alkenoyloxy derivatives of milbemycin and related macrolides, their preparation and their use
AU1907788A (en) N-aminobutyl-n-phenylarylamide derivatives, their preparation and their application in therapy
NZ212673A (en) Avermectin and milbemycin derivatives and parasiticidal compositions
AU640421B2 (en) 24-and 25-substituted avermectin and milbemycin derivatives
AU2156588A (en) Tetrahydroindazolyl-benzoxazines, their production and use
AU1740488A (en) Phenol derivatives, their production and use
IL75428A0 (en) Milbemycin derivatives,their preparation and their use as pesticides
GB2226027B (en) Adenosine derivatives,their production and use
EP0320988A3 (en) Epipodophyllotoxin glucoside 4'-acyl derivative
AU2383588A (en) Polyaldehydic polynucleotides in use as probes, their preparation and use
IL85869A0 (en) Milbemycin derivatives,their preparation and their use as parasiticides and insecticides
AU627033B2 (en) 1-phenyl-1,4-dihydro-3-amino-4-oxopyridazine derivatives, their preparation and their application in therapy

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired