IL84214A - 4,5-dihydro and 4,5,6,7- tetrahydropyrazolo (1,5-a) pyrimidines, their preparation, pharmaceutical compositions containing them and chemical intermediates thereof - Google Patents

4,5-dihydro and 4,5,6,7- tetrahydropyrazolo (1,5-a) pyrimidines, their preparation, pharmaceutical compositions containing them and chemical intermediates thereof

Info

Publication number
IL84214A
IL84214A IL84214A IL8421487A IL84214A IL 84214 A IL84214 A IL 84214A IL 84214 A IL84214 A IL 84214A IL 8421487 A IL8421487 A IL 8421487A IL 84214 A IL84214 A IL 84214A
Authority
IL
Israel
Prior art keywords
tetrahydropyrazolo
pyrimidines
dihydro
preparation
pharmaceutical compositions
Prior art date
Application number
IL84214A
Other languages
English (en)
Other versions
IL84214A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/919,730 external-priority patent/US4847256A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL84214A0 publication Critical patent/IL84214A0/xx
Publication of IL84214A publication Critical patent/IL84214A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL84214A 1986-10-16 1987-10-19 4,5-dihydro and 4,5,6,7- tetrahydropyrazolo (1,5-a) pyrimidines, their preparation, pharmaceutical compositions containing them and chemical intermediates thereof IL84214A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91973186A 1986-10-16 1986-10-16
US06/919,730 US4847256A (en) 1986-10-16 1986-10-16 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo(1,5-A)-pyrimidines

Publications (2)

Publication Number Publication Date
IL84214A0 IL84214A0 (en) 1988-03-31
IL84214A true IL84214A (en) 1993-05-13

Family

ID=27129779

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84214A IL84214A (en) 1986-10-16 1987-10-19 4,5-dihydro and 4,5,6,7- tetrahydropyrazolo (1,5-a) pyrimidines, their preparation, pharmaceutical compositions containing them and chemical intermediates thereof

Country Status (10)

Country Link
EP (1) EP0264773A1 (pt)
KR (1) KR880005132A (pt)
AU (1) AU601498B2 (pt)
DK (1) DK539087A (pt)
FI (1) FI87459C (pt)
HU (1) HU203103B (pt)
IL (1) IL84214A (pt)
NO (1) NO171067C (pt)
NZ (1) NZ222179A (pt)
PT (1) PT85936B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963553A (en) * 1986-10-16 1990-10-16 American Cyanamid Co. 4-[(substituted) alkylcarbonyl]-4,5-dihydro- and -4,5,6,7-tetrahydro-7-[(substituted)phenyl]pyrazolo[1,5-a]pyrimidines
US5126340A (en) * 1986-10-16 1992-06-30 American Cyanamid Company 4-[(substituted)alkylcarbonyl]-4,5-dihydro and -4,5,6,7-tetrahydro-7-[(substituted)-phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitriles
US5219857A (en) * 1986-10-16 1993-06-15 American Cyanamid Company Method of treating cognitive and related neural behavioral problems
DE68911951T2 (de) * 1988-02-22 1994-06-01 American Cyanamid Co 5-(Substituierte Amino)-8-(phenyl oder substituierte phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one.
US4963552A (en) * 1989-08-28 1990-10-16 American Cyanamid Company 1-substitute-1,2-dihydro-4-((substituted)phenyl)imidazo-[1,5-a]pyrimidine-8-carbonitriles
DE4133957A1 (de) * 1991-10-14 1993-04-15 Wella Ag Haarfaerbemittel mit einem gehalt an aminopyrazolderivaten sowie neue pyrazolderivate
SG47588A1 (en) * 1992-03-26 1998-04-17 American Cyanamid Co An improved process for the synthesis of 5-[(substituted) amino] -8- [phenyl or substituted-phenyl]-3H, 6H-1, 4, 5A, 8A-tetraazaacenaphtylen-3- ones
GB0016787D0 (en) 2000-07-07 2000-08-30 Pfizer Ltd Compounds useful in therapy
DE10153344A1 (de) * 2001-10-29 2003-05-15 Gruenenthal Gmbh Verwendung von substituierten Pyrazolopyrimidinen als Liganden von Nucleosid-Transport-Proteinen und/oder von Purinorezeptoren
BR0208244A (pt) 2001-03-14 2004-03-02 Gr Nenthal Gmbh Pirazolo-e tiazolopirinidinas substituìdas
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
TWI252851B (en) * 2003-07-24 2006-04-11 Ferrer Int 7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
WO2006033795A2 (en) * 2004-09-17 2006-03-30 Wyeth Substituted pyrazolo [1, 5-a] pyrimidines for inhibiting abnormal cell growth
WO2006033796A1 (en) * 2004-09-17 2006-03-30 Wyeth SUBSTITUTED PYRAZOLO [1,5-a] PYRIMIDINES AND PROCESS FOR MAKING SAME

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
US4521422A (en) * 1983-06-23 1985-06-04 American Cyanamid Company Aryl and heteroaryl[7-(aryl and heteroaryl)pyrazolo[1,5-a]pyrimidin-3-yl]methanones
NZ208554A (en) * 1983-06-23 1987-06-30 American Cyanamid Co (aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
DK539087D0 (da) 1987-10-15
AU601498B2 (en) 1990-09-13
NO171067C (no) 1993-01-20
HUT47276A (en) 1989-02-28
EP0264773A1 (en) 1988-04-27
IL84214A0 (en) 1988-03-31
NO171067B (no) 1992-10-12
FI87459C (fi) 1993-01-11
PT85936B (pt) 1990-07-31
KR880005132A (ko) 1988-06-28
FI874547A0 (fi) 1987-10-15
DK539087A (da) 1988-04-17
NO874302L (no) 1988-04-18
HU203103B (en) 1991-05-28
PT85936A (en) 1987-11-01
NZ222179A (en) 1991-01-29
NO874302D0 (no) 1987-10-15
FI874547A (fi) 1988-04-17
FI87459B (fi) 1992-09-30
AU7980087A (en) 1988-04-21

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Legal Events

Date Code Title Description
RH Patent void