IL80349A - Hydrophobic cis-platinum complexes,their preparation,liposomes containing them and pharmaceutical compositions containing the liposomes - Google Patents

Hydrophobic cis-platinum complexes,their preparation,liposomes containing them and pharmaceutical compositions containing the liposomes

Info

Publication number
IL80349A
IL80349A IL80349A IL8034986A IL80349A IL 80349 A IL80349 A IL 80349A IL 80349 A IL80349 A IL 80349A IL 8034986 A IL8034986 A IL 8034986A IL 80349 A IL80349 A IL 80349A
Authority
IL
Israel
Prior art keywords
liposomes
complex
platinum
preparation
pharmaceutical compositions
Prior art date
Application number
IL80349A
Other languages
English (en)
Other versions
IL80349A0 (en
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27120836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL80349(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Texas filed Critical Univ Texas
Publication of IL80349A0 publication Critical patent/IL80349A0/xx
Publication of IL80349A publication Critical patent/IL80349A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
IL80349A 1985-10-18 1986-10-17 Hydrophobic cis-platinum complexes,their preparation,liposomes containing them and pharmaceutical compositions containing the liposomes IL80349A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78875085A 1985-10-18 1985-10-18
US06/914,591 US5041581A (en) 1985-10-18 1986-10-07 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Publications (2)

Publication Number Publication Date
IL80349A0 IL80349A0 (en) 1987-01-30
IL80349A true IL80349A (en) 1991-06-30

Family

ID=27120836

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80349A IL80349A (en) 1985-10-18 1986-10-17 Hydrophobic cis-platinum complexes,their preparation,liposomes containing them and pharmaceutical compositions containing the liposomes

Country Status (10)

Country Link
US (3) US5041581A (de)
EP (1) EP0248036B1 (de)
KR (1) KR900003094B1 (de)
AT (1) ATE77384T1 (de)
CA (1) CA1312616C (de)
DE (1) DE3685751T2 (de)
DK (1) DK307787A (de)
FI (1) FI85492C (de)
IL (1) IL80349A (de)
WO (1) WO1987002364A1 (de)

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US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5206400A (en) * 1986-07-07 1993-04-27 Ohio State University Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof
US5320906A (en) * 1986-12-15 1994-06-14 Vestar, Inc. Delivery vehicles with amphiphile-associated active ingredient
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IL85595A0 (en) * 1987-03-06 1988-08-31 Tanabe Seiyaku Co Organic platinum complex and its preparation
DE3710371A1 (de) * 1987-03-28 1988-10-13 Dornier Medizintechnik Zerstoerung von krankhaft veraenderten gewebezellen
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US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
CA2263455C (en) * 1996-08-23 2002-10-29 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6548541B1 (en) * 1999-04-21 2003-04-15 Unitech Pharmaceuticals, Inc. Carboplatin analogs for cancer treatment
EP2266607A3 (de) 1999-10-01 2011-04-20 Immunogen, Inc. Immunokonjugate für Krebsbehandlung
EP1424889A4 (de) * 2001-08-20 2008-04-02 Transave Inc Verfahren zur behandlung von lungenkarzinomen
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
US9186322B2 (en) 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US20040101553A1 (en) * 2002-08-02 2004-05-27 Transave, Inc. Platinum aggregates and process for producing the same
DK1581236T3 (da) * 2002-10-29 2013-12-02 Insmed Inc Opretholdt afgivelse af antiinfektionsmidler
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
US7160908B2 (en) * 2003-03-04 2007-01-09 Unitech Pharmaceuticals, Inc. Dynamic anticancer platinum compounds
WO2004098524A2 (en) * 2003-05-02 2004-11-18 Aronex Pharmaceuticals, Inc. Lipid platinum complexes and methods of use thereof
EP1631301A4 (de) * 2003-05-20 2006-06-07 Aronex Pharmaceuticals Inc Kombinationschemotherapie mit 5-fluorouracil oder einem derivat davon und einem liposomalen platinkomplex
WO2004105747A1 (en) * 2003-05-20 2004-12-09 Aronex Pharmaceuticals, Inc Combination chemotherapy comprising capecitabine and a liposomal platinum complex
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
EP1631258A1 (de) * 2003-05-20 2006-03-08 Aronex Pharmaceuticals Inc. Kombinationschemotherapie mit gemcitabin und einem liposomalen platinkomplex
WO2005044236A1 (en) * 2003-10-27 2005-05-19 Control Delivery Systems, Inc. Suspension delivery system for the sustained and controlled local release of pharmaceuticals
US20070065522A1 (en) * 2004-03-18 2007-03-22 Transave, Inc. Administration of high potency platinum compound formulations by inhalation
CN1976711A (zh) * 2004-03-18 2007-06-06 特兰萨维股份有限公司 通过吸入给药顺铂
AU2005245018A1 (en) * 2004-05-21 2005-12-01 Transave, Inc. Treatment of lung diseases and pre-lung disease conditions
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JP2008536874A (ja) 2005-04-15 2008-09-11 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 中性脂質組成物によるｓｉＲＮＡの送達
CN1913508B (zh) * 2005-08-08 2010-05-05 华为技术有限公司 基于正交频分复用的信号调制方法及其调制装置
US20070190182A1 (en) * 2005-11-08 2007-08-16 Pilkiewicz Frank G Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
PL1962805T3 (pl) 2005-12-08 2017-01-31 Insmed Incorporated Kompozycje środków przeciwzapalnych oparte na lipidach do leczenia infekcji płucnych
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
FR2945946B1 (fr) 2009-05-29 2011-08-26 Univ Victor Segalen Bordeaux 2 Formulations a compartiments multiples a base de molecules ou macromolecules amphiphiles fonctionnelles
PT2852391T (pt) 2012-05-21 2022-02-18 Insmed Inc Sistemas para tratamento de infeções pulmonares
CN115414384A (zh) 2012-09-04 2022-12-02 埃莱森制药有限责任公司 用顺铂脂质复合物预防癌症的肺部复发
RU2018135921A (ru) 2012-11-29 2019-02-05 Инсмед Инкорпорейтед Стабилизированные составы ванкомицина
MX376012B (es) 2014-05-15 2025-03-07 Insmed Inc Metodos para tratar infecciones pulmonares micobacterianas no tuberculosas.
US20170208825A1 (en) * 2016-01-21 2017-07-27 Alan Backus Gaseous transfer device
US10925831B2 (en) * 2017-08-28 2021-02-23 Wake Forest University Liposomal formulations of platinum-acridine anticancer agents and methods thereof
JP7460534B2 (ja) 2018-03-30 2024-04-02 インスメッド インコーポレイテッド リポソーム医薬品の連続製造方法
US20210113467A1 (en) 2018-05-02 2021-04-22 Robert Worsham Methods for the manufacture of liposomal drug formulations

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Also Published As

Publication number Publication date
DK307787A (da) 1987-08-17
DE3685751D1 (de) 1992-07-23
FI85492C (fi) 1992-04-27
DE3685751T2 (de) 1993-02-04
DK307787D0 (da) 1987-06-17
FI872646L (fi) 1987-06-15
US5041581A (en) 1991-08-20
CA1312616C (en) 1993-01-12
WO1987002364A1 (en) 1987-04-23
EP0248036B1 (de) 1992-06-17
KR900003094B1 (ko) 1990-05-07
KR870700631A (ko) 1987-12-30
FI872646A0 (fi) 1987-06-15
US5178876A (en) 1993-01-12
EP0248036A1 (de) 1987-12-09
FI85492B (fi) 1992-01-15
ATE77384T1 (de) 1992-07-15
US5186940A (en) 1993-02-16
IL80349A0 (en) 1987-01-30

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