ATE77384T1 - In liposomen inkorporierte hydrophobe cis-platin- komplexe. - Google Patents

In liposomen inkorporierte hydrophobe cis-platin- komplexe.

Info

Publication number
ATE77384T1
ATE77384T1 AT86906624T AT86906624T ATE77384T1 AT E77384 T1 ATE77384 T1 AT E77384T1 AT 86906624 T AT86906624 T AT 86906624T AT 86906624 T AT86906624 T AT 86906624T AT E77384 T1 ATE77384 T1 AT E77384T1
Authority
AT
Austria
Prior art keywords
liposomes
complex
platinum
platinum complexes
carboxylato
Prior art date
Application number
AT86906624T
Other languages
English (en)
Inventor
Abdul R Khokhar
Gabriel Lopez-Berestein
Roman Perez-Soler
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27120836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE77384(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE77384T1 publication Critical patent/ATE77384T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT86906624T 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin- komplexe. ATE77384T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78875085A 1985-10-18 1985-10-18
US06/914,591 US5041581A (en) 1985-10-18 1986-10-07 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
EP86906624A EP0248036B1 (de) 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin-komplexe
PCT/US1986/002181 WO1987002364A1 (en) 1985-10-18 1986-10-17 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Publications (1)

Publication Number Publication Date
ATE77384T1 true ATE77384T1 (de) 1992-07-15

Family

ID=27120836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86906624T ATE77384T1 (de) 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin- komplexe.

Country Status (10)

Country Link
US (3) US5041581A (de)
EP (1) EP0248036B1 (de)
KR (1) KR900003094B1 (de)
AT (1) ATE77384T1 (de)
CA (1) CA1312616C (de)
DE (1) DE3685751T2 (de)
DK (1) DK307787A (de)
FI (1) FI85492C (de)
IL (1) IL80349A (de)
WO (1) WO1987002364A1 (de)

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US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
DE69725747T2 (de) * 1996-08-23 2004-07-29 Sequus Pharmaceuticals, Inc., Menlo Park Liposome enthaltend cisplatin
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
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US20070065522A1 (en) * 2004-03-18 2007-03-22 Transave, Inc. Administration of high potency platinum compound formulations by inhalation
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US20060034906A1 (en) * 2004-05-21 2006-02-16 Transave, Inc. Treatment of lung diseases and pre-lung disease conditions
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WO2006113679A2 (en) 2005-04-15 2006-10-26 Board Of Regents, The University Of Texas System Delivery of sirna by neutral lipid compositions
CN1913508B (zh) * 2005-08-08 2010-05-05 华为技术有限公司 基于正交频分复用的信号调制方法及其调制装置
WO2007056264A2 (en) * 2005-11-08 2007-05-18 Transave, Inc. Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
JP5324223B2 (ja) 2005-12-08 2013-10-23 トランセイブ， インク． 肺感染症を治療する抗感染薬の脂質ベースの組成物及びその使用法
US20100196455A1 (en) 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
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FR2945946B1 (fr) 2009-05-29 2011-08-26 Univ Victor Segalen Bordeaux 2 Formulations a compartiments multiples a base de molecules ou macromolecules amphiphiles fonctionnelles
PL2852391T3 (pl) 2012-05-21 2022-04-11 Insmed Incorporated Układy do leczenia infekcji płuc
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Also Published As

Publication number Publication date
EP0248036B1 (de) 1992-06-17
CA1312616C (en) 1993-01-12
US5186940A (en) 1993-02-16
KR870700631A (ko) 1987-12-30
DK307787D0 (da) 1987-06-17
FI872646A0 (fi) 1987-06-15
DE3685751D1 (de) 1992-07-23
FI872646L (fi) 1987-06-15
EP0248036A1 (de) 1987-12-09
FI85492B (fi) 1992-01-15
KR900003094B1 (ko) 1990-05-07
US5178876A (en) 1993-01-12
DK307787A (da) 1987-08-17
DE3685751T2 (de) 1993-02-04
IL80349A0 (en) 1987-01-30
WO1987002364A1 (en) 1987-04-23
IL80349A (en) 1991-06-30
FI85492C (fi) 1992-04-27
US5041581A (en) 1991-08-20

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