ATE77384T1 - In liposomen inkorporierte hydrophobe cis-platin- komplexe. - Google Patents

In liposomen inkorporierte hydrophobe cis-platin- komplexe.

Info

Publication number
ATE77384T1
ATE77384T1 AT86906624T AT86906624T ATE77384T1 AT E77384 T1 ATE77384 T1 AT E77384T1 AT 86906624 T AT86906624 T AT 86906624T AT 86906624 T AT86906624 T AT 86906624T AT E77384 T1 ATE77384 T1 AT E77384T1
Authority
AT
Austria
Prior art keywords
liposomes
complex
platinum
platinum complexes
carboxylato
Prior art date
Application number
AT86906624T
Other languages
English (en)
Inventor
Abdul R Khokhar
Gabriel Lopez-Berestein
Roman Perez-Soler
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27120836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE77384(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE77384T1 publication Critical patent/ATE77384T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT86906624T 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin- komplexe. ATE77384T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78875085A 1985-10-18 1985-10-18
US06/914,591 US5041581A (en) 1985-10-18 1986-10-07 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
PCT/US1986/002181 WO1987002364A1 (en) 1985-10-18 1986-10-17 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
EP86906624A EP0248036B1 (de) 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin-komplexe

Publications (1)

Publication Number Publication Date
ATE77384T1 true ATE77384T1 (de) 1992-07-15

Family

ID=27120836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86906624T ATE77384T1 (de) 1985-10-18 1986-10-17 In liposomen inkorporierte hydrophobe cis-platin- komplexe.

Country Status (10)

Country Link
US (3) US5041581A (de)
EP (1) EP0248036B1 (de)
KR (1) KR900003094B1 (de)
AT (1) ATE77384T1 (de)
CA (1) CA1312616C (de)
DE (1) DE3685751T2 (de)
DK (1) DK307787A (de)
FI (1) FI85492C (de)
IL (1) IL80349A (de)
WO (1) WO1987002364A1 (de)

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US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6548541B1 (en) * 1999-04-21 2003-04-15 Unitech Pharmaceuticals, Inc. Carboplatin analogs for cancer treatment
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WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
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CN1913508B (zh) * 2005-08-08 2010-05-05 华为技术有限公司 基于正交频分复用的信号调制方法及其调制装置
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US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
PL1962805T3 (pl) 2005-12-08 2017-01-31 Insmed Incorporated Kompozycje środków przeciwzapalnych oparte na lipidach do leczenia infekcji płucnych
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US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
FR2945946B1 (fr) 2009-05-29 2011-08-26 Univ Victor Segalen Bordeaux 2 Formulations a compartiments multiples a base de molecules ou macromolecules amphiphiles fonctionnelles
PT2852391T (pt) 2012-05-21 2022-02-18 Insmed Inc Sistemas para tratamento de infeções pulmonares
CN115414384A (zh) 2012-09-04 2022-12-02 埃莱森制药有限责任公司 用顺铂脂质复合物预防癌症的肺部复发
RU2018135921A (ru) 2012-11-29 2019-02-05 Инсмед Инкорпорейтед Стабилизированные составы ванкомицина
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US10925831B2 (en) * 2017-08-28 2021-02-23 Wake Forest University Liposomal formulations of platinum-acridine anticancer agents and methods thereof
JP7460534B2 (ja) 2018-03-30 2024-04-02 インスメッド インコーポレイテッド リポソーム医薬品の連続製造方法
US20210113467A1 (en) 2018-05-02 2021-04-22 Robert Worsham Methods for the manufacture of liposomal drug formulations

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Also Published As

Publication number Publication date
DK307787A (da) 1987-08-17
DE3685751D1 (de) 1992-07-23
FI85492C (fi) 1992-04-27
DE3685751T2 (de) 1993-02-04
DK307787D0 (da) 1987-06-17
FI872646L (fi) 1987-06-15
US5041581A (en) 1991-08-20
CA1312616C (en) 1993-01-12
WO1987002364A1 (en) 1987-04-23
IL80349A (en) 1991-06-30
EP0248036B1 (de) 1992-06-17
KR900003094B1 (ko) 1990-05-07
KR870700631A (ko) 1987-12-30
FI872646A0 (fi) 1987-06-15
US5178876A (en) 1993-01-12
EP0248036A1 (de) 1987-12-09
FI85492B (fi) 1992-01-15
US5186940A (en) 1993-02-16
IL80349A0 (en) 1987-01-30

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