IL78824A - Process for the extraction and purification of proteins from culture media producing them - Google Patents

Process for the extraction and purification of proteins from culture media producing them

Info

Publication number
IL78824A
IL78824A IL78824A IL7882486A IL78824A IL 78824 A IL78824 A IL 78824A IL 78824 A IL78824 A IL 78824A IL 7882486 A IL7882486 A IL 7882486A IL 78824 A IL78824 A IL 78824A
Authority
IL
Israel
Prior art keywords
proteins
purification
extraction
culture media
media producing
Prior art date
Application number
IL78824A
Other languages
English (en)
Other versions
IL78824A0 (en
Original Assignee
Smithkline Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Biolog filed Critical Smithkline Biolog
Publication of IL78824A0 publication Critical patent/IL78824A0/xx
Publication of IL78824A publication Critical patent/IL78824A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/063—Lysis of microorganisms of yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL78824A 1985-04-03 1986-02-24 Process for the extraction and purification of proteins from culture media producing them IL78824A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/719,601 US4683294A (en) 1985-04-03 1985-04-03 Process for the extraction and purification of proteins from culture media producing them

Publications (2)

Publication Number Publication Date
IL78824A0 IL78824A0 (en) 1986-09-30
IL78824A true IL78824A (en) 1991-04-15

Family

ID=24890650

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78824A IL78824A (en) 1985-04-03 1986-02-24 Process for the extraction and purification of proteins from culture media producing them

Country Status (29)

Country Link
US (2) US4683294A (zh)
EP (1) EP0199698B1 (zh)
JP (1) JP2512430B2 (zh)
KR (1) KR940010283B1 (zh)
CN (1) CN86101798A (zh)
AR (1) AR241596A1 (zh)
AT (1) ATE66694T1 (zh)
AU (1) AU580494B2 (zh)
CA (1) CA1272457A (zh)
CS (1) CS259537B2 (zh)
DE (1) DE3681058D1 (zh)
DK (1) DK152286A (zh)
EG (1) EG17972A (zh)
ES (1) ES8706166A1 (zh)
FI (1) FI85027C (zh)
GR (1) GR860874B (zh)
HU (1) HU206125B (zh)
IE (1) IE58854B1 (zh)
IL (1) IL78824A (zh)
MY (1) MY102936A (zh)
NO (1) NO170421C (zh)
NZ (1) NZ215618A (zh)
PH (1) PH22110A (zh)
PL (1) PL152568B1 (zh)
PT (1) PT82219B (zh)
RO (1) RO95349B (zh)
SU (1) SU1604144A3 (zh)
YU (1) YU46304B (zh)
ZA (1) ZA862374B (zh)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1268437A (en) * 1984-12-21 1990-05-01 Haruo Fujita Method for purification of hbc antigen and method for measurement of hbc antibody by using said purified hbc antigen
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
US5124256A (en) * 1985-11-13 1992-06-23 Labofina, S.A. Process for recovering polypeptides localized in the periplasmic space of yeast without breaking the cell wall by using an non-ionic detergent and a neutral salt
US4742158A (en) * 1986-04-25 1988-05-03 Merck & Co., Inc. Purification of hepatitis pre-S antigens by polymerized serum albumin affinity binding
FR2608052B1 (fr) * 1986-12-10 1990-04-13 Pasteur Vaccins Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu
AP56A (en) * 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
NZ225583A (en) * 1987-08-06 1991-07-26 Merck & Co Inc Process for purifying hepatitis a virions (hav)
US4883865A (en) * 1987-09-30 1989-11-28 Merck & Co. Inc. Recovery of pres2+s antigen
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
US5043287A (en) * 1989-05-16 1991-08-27 The Standard Oil Company Recovery of water soluble biopolymers from an aqueous solution by employing a polyoxide
US5139943A (en) * 1989-06-13 1992-08-18 Genencor International, Inc. Processes for the recovery of microbially produced chymosin
US5151358A (en) * 1989-06-13 1992-09-29 Genencor International, Inc. Processes for the recovery of naturally produced chymosin
ES2045669T3 (es) * 1989-07-15 1994-01-16 Boehringer Ingelheim Int Procedimiento para la purificacion de anexinas.
US4988798A (en) * 1990-01-22 1991-01-29 Pitman-Moore, Inc. Method for recovering recombinant proteins
US5109121A (en) * 1990-01-22 1992-04-28 Pitman-Moore, Inc. Method for recovering recombinant proteins
US5177194A (en) * 1990-02-01 1993-01-05 Baxter International, Inc. Process for purifying immune serum globulins
US5290474A (en) * 1990-10-05 1994-03-01 Genencor International, Inc. Detergent composition for treating cotton-containing fabrics containing a surfactant and a cellulase composition containing endolucanase III from trichoderma ssp
US5328841A (en) * 1990-10-05 1994-07-12 Genencor International, Inc. Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol
CA2093422C (en) * 1990-10-05 2001-04-03 DETERGENT COMPOSITIONS CONTAINING LOW CBH I CONTENT CELLULASE COMPOSITIONS
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
US5525519A (en) * 1992-01-07 1996-06-11 Middlesex Sciences, Inc. Method for isolating biomolecules from a biological sample with linear polymers
US6509192B1 (en) * 1992-02-24 2003-01-21 Coulter International Corp. Quality control method
US6362003B1 (en) 1992-02-24 2002-03-26 Coulter Corporation Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof
HRP950097A2 (en) 1994-03-08 1997-06-30 Merck & Co Inc Hepatitis a virus culture process
KR100254828B1 (ko) * 1994-12-24 2000-05-01 성재갑 재조합 효모로 부터 발현된 b형 간염 항원의 추출 방법
US5869604A (en) * 1995-11-09 1999-02-09 Georgia Institute Of Technology Crystallization and purification of polypeptides
UA79735C2 (uk) * 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
ATE489400T1 (de) 2002-09-06 2010-12-15 Genentech Inc Verfahren zur proteinextraktion
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
US8323949B2 (en) * 2003-03-11 2012-12-04 Advanced Biocatalytics Corporation Altering metabolism in biological processes
US7476529B2 (en) * 2003-03-11 2009-01-13 Advanced Biocatalytics Corporation Altering metabolism in biological processes
WO2005027821A2 (en) * 2003-09-22 2005-03-31 Kamada Ltd. Large scale preparation of alpha-1 proteinase inhibitor and use thereof
AU2004309177A1 (en) * 2003-12-30 2005-07-14 Bharat Biotech International Limited A process for the preparation and purification of recombinant proteins
SE0400886D0 (sv) * 2004-04-02 2004-04-02 Amersham Biosciences Ab Process of purification
CN1314447C (zh) * 2004-04-12 2007-05-09 爱华生物科技(香港)有限公司 一种具有抑制蛋白酶作用的药物的制备方法
US8119146B2 (en) 2005-04-18 2012-02-21 Angelica Medina-Selby Expressing hepatitis B virus surface antigen for vaccine preparation
EP1909830B1 (en) * 2005-08-02 2011-09-28 Novartis Vaccines and Diagnostics S.r.l. Reducing interference between oil-containing adjuvants and surfactant-containing antigens
WO2008127305A2 (en) * 2006-11-01 2008-10-23 Biogen Idec Ma Inc. Method of isolating biomacromolecules using low ph and divalent cations
US11051532B2 (en) 2017-09-22 2021-07-06 Impossible Foods Inc. Methods for purifying protein
EP3670646A1 (en) * 2018-12-21 2020-06-24 Ohly GmbH Functional yeast protein concentrate
US12011016B2 (en) 2020-09-14 2024-06-18 Impossible Foods Inc. Protein methods and compositions

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
US3790552A (en) * 1972-03-16 1974-02-05 Us Health Method of removing hepatitis-associated antigen from a protein fraction using polyethylene glycol
US3994879A (en) * 1972-12-18 1976-11-30 Hoechst Aktiengesellschaft Process for the preparation of benzofuran compounds
US3951937A (en) * 1973-12-20 1976-04-20 The Community Blood Council Of Greater New York, Inc. Large scale purification of hepatitis type B antigen using polyethylene glycol
US3994870A (en) * 1974-01-31 1976-11-30 The Community Blood Council Of Greater New York, Inc. Purification of hepatitis B surface antigen
SE437329B (sv) * 1975-03-14 1985-02-25 Community Blood Council Sett att ur blodserum framstella vaccin mot virushepatit
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration
US4113712A (en) * 1976-03-08 1978-09-12 The Green Cross Corporation HBsAG Particle composed of single polypeptide subunits and the preparation procedure
GB1589581A (en) * 1976-04-14 1981-05-13 Biotechnolog Forschung Gmbh Process for the separation of enzymes
US4102996A (en) * 1977-04-20 1978-07-25 Merck & Co., Inc. Method of preparing hepatitis B core antigen
DE2750045A1 (de) * 1977-11-09 1979-05-10 Behringwerke Ag Verfahren zur entfernung von detergentien aus virusantigensuspensionen
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus
US4349539A (en) * 1980-08-15 1982-09-14 Merck & Co., Inc. Separation of hepatitis B surface antigen
US4314997A (en) * 1980-10-06 1982-02-09 Edward Shanbrom Purification of plasma protein products
JPH0625069B2 (ja) * 1981-01-29 1994-04-06 ブリティッシュ・テクノロジー・グループ・リミテッド Ｂ型肝炎ワクチン製造方法
US4542016A (en) * 1981-03-27 1985-09-17 Institut Merieux Non-a non-b hepatitis surface antigen useful for the preparation of vaccines and methods of use
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
PL133476B1 (en) * 1981-06-10 1985-06-29 Akad Medyczna Method of obtaining pure antigen hba from human serum
US4379087A (en) * 1982-06-17 1983-04-05 Cutter Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
AU584580B2 (en) * 1982-09-08 1989-06-01 Smith Kline - Rit Hepatitis B virus vaccine
SE8205892D0 (sv) * 1982-10-18 1982-10-18 Bror Morein Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
JPS59101426A (ja) * 1982-11-29 1984-06-12 Green Cross Corp:The Ｂ型肝炎感染予防用ワクチンの製造方法
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
US4649192A (en) * 1985-05-30 1987-03-10 Smith Kline-Rit Method for the isolation and purification of hepatitis B surface antigen using polysorbate

Also Published As

Publication number Publication date
US4857317A (en) 1989-08-15
IL78824A0 (en) 1986-09-30
PL152568B1 (en) 1991-01-31
US4683294A (en) 1987-07-28
FI861251A (fi) 1986-10-04
NZ215618A (en) 1988-08-30
ATE66694T1 (de) 1991-09-15
AU5378686A (en) 1986-10-09
PH22110A (en) 1988-06-01
ZA862374B (en) 1987-06-24
EP0199698A2 (fr) 1986-10-29
YU46304B (sh) 1993-05-28
YU46386A (en) 1988-02-29
AR241596A1 (es) 1992-09-30
PT82219A (en) 1986-04-01
JPS61249398A (ja) 1986-11-06
SU1604144A3 (ru) 1990-10-30
IE58854B1 (en) 1993-11-17
RO95349A (ro) 1988-09-15
JP2512430B2 (ja) 1996-07-03
DK152286A (da) 1986-10-04
EP0199698A3 (en) 1989-05-24
HU206125B (en) 1992-08-28
ES553633A0 (es) 1987-06-01
NO861234L (no) 1986-10-06
MY102936A (en) 1993-03-31
CS223386A2 (en) 1988-02-15
RO95349B (ro) 1988-09-16
CS259537B2 (en) 1988-10-14
FI85027B (fi) 1991-11-15
NO170421B (no) 1992-07-06
CN86101798A (zh) 1986-10-15
IE860826L (en) 1986-10-03
CA1272457A (en) 1990-08-07
ES8706166A1 (es) 1987-06-01
GR860874B (en) 1986-07-30
HUT40810A (en) 1987-02-27
KR860008276A (ko) 1986-11-14
DK152286D0 (da) 1986-04-03
DE3681058D1 (de) 1991-10-02
AU580494B2 (en) 1989-01-12
NO170421C (no) 1992-10-14
KR940010283B1 (ko) 1994-10-22
PT82219B (pt) 1988-02-17
EP0199698B1 (fr) 1991-08-28
EG17972A (en) 1991-06-30
FI861251A0 (fi) 1986-03-24
FI85027C (fi) 1992-02-25

Similar Documents

Publication Publication Date Title
EG17972A (en) Process for the extraction and purification of proteins from culture media producing them
HUT39462A (en) Process for the purification of proteins
ZA875841B (en) Method of culturing leukocytes
GB2171102B (en) Process for the purification of proteins from milk and from its derivatives
EP0216486A3 (en) Acid gas removal process
GB2179947B (en) Process for the extraction of proteins from milk
AP8800077A0 (en) Process for production of avermecting and cultures thereof
EP0218249A3 (en) 3-aminopyrrolidines and process for their production
PT82917A (en) Process for the preparation of modified enzymes
IL78874A0 (en) Method of preparing vaccines and process for the production thereof
ZA858412B (en) Process for the preparation and purification of peptides
GB8521359D0 (en) Fermentation process
GB2182057B (en) Gas separation process
EP0258730A3 (en) Process for the production of magnetic-recording media
GR3000404T3 (en) Process for the separation and purification of salicylic acid
HU900124D0 (en) Process and solventmixture for purification of amfotericyn b
GB8810535D0 (en) Process for purification of gases
EP0256812A3 (en) Process for separation of n-protected -alpha-l-aspartyl-l-phenylalines
GB2179057B (en) Process for the production of biogas
AR242946A1 (es) Procedimiento de separacion y de purificacion del acido parahidroxibenzoico.
HUT34547A (en) Process for the purification of proteins isolated from microbe cultures
GB2180167B (en) Acid gas removal process
HUT38890A (en) Process for separation of geometrical izomers of cycloprophan carbonic acids
HUT44031A (en) Process for production of the piparasine-derivatives of teofillin and teobromin
IL78823A0 (en) Process for the purification of 5-pyrimidinecarboxamides

Legal Events

Date Code Title Description
RH Patent void