IL78452A - Process for purification of tissue plasminogen activator (t-pa) - Google Patents

Process for purification of tissue plasminogen activator (t-pa)

Info

Publication number
IL78452A
IL78452A IL78452A IL7845286A IL78452A IL 78452 A IL78452 A IL 78452A IL 78452 A IL78452 A IL 78452A IL 7845286 A IL7845286 A IL 7845286A IL 78452 A IL78452 A IL 78452A
Authority
IL
Israel
Prior art keywords
plasminogen activator
tissue plasminogen
purification
bound
affinity material
Prior art date
Application number
IL78452A
Other languages
English (en)
Other versions
IL78452A0 (en
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of IL78452A0 publication Critical patent/IL78452A0/xx
Publication of IL78452A publication Critical patent/IL78452A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL78452A 1985-04-11 1986-04-08 Process for purification of tissue plasminogen activator (t-pa) IL78452A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853512910 DE3512910A1 (de) 1985-04-11 1985-04-11 Verfahren zur reinigung von plasminogenaktivatoren

Publications (2)

Publication Number Publication Date
IL78452A0 IL78452A0 (en) 1986-08-31
IL78452A true IL78452A (en) 1993-01-31

Family

ID=6267676

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78452A IL78452A (en) 1985-04-11 1986-04-08 Process for purification of tissue plasminogen activator (t-pa)

Country Status (11)

Country Link
US (1) US5015583A (da)
EP (1) EP0210332B1 (da)
JP (1) JPH084500B2 (da)
AT (1) ATE49420T1 (da)
AU (1) AU603544B2 (da)
DE (2) DE3512910A1 (da)
DK (1) DK161986A (da)
ES (1) ES8703522A1 (da)
IL (1) IL78452A (da)
MX (1) MX167325B (da)
NO (1) NO174111C (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8710813U1 (de) * 1987-08-07 1987-09-24 Rhein-Conti Kunststoff-Technik Gmbh, 6900 Heidelberg Tankstutzen mit Verschraubung von oben
US5225330A (en) * 1988-08-01 1993-07-06 The United States Of America As Represented By The Department Of Health And Human Services Diagnostic kit and diagnostic method utilizing carbohydrate receptors
US6207151B1 (en) * 1989-09-21 2001-03-27 Mitsui Chemicals Inc. Aqueous solution of t-PA
JP2520975B2 (ja) * 1989-09-21 1996-07-31 三井東圧化学株式会社 組織プラスミノ―ゲンアクチベ―タ―若しくはその誘導体を含有する血栓溶解剤
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
US20020076728A1 (en) * 1997-03-21 2002-06-20 Maclennan John Moore Engineering affinity ligands for macromolecules

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH64754A (de) * 1913-06-24 1914-04-16 Bern Giesserei Anzeigeeinrichtung an Reibungskupplungen
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
US3943245A (en) * 1974-02-14 1976-03-09 Armour Pharmaceutical Company Purification of plasminogen
NZ187246A (en) * 1976-03-04 1980-05-27 New Zealand Dev Finance Hydrophilic hydroxy c2-c4 alkylated crosslinked regenerated cellulose
CH626917A5 (da) * 1976-08-17 1981-12-15 Pentapharm Ag
US4066506A (en) * 1976-10-08 1978-01-03 The United States Of America As Represented By The Secretary Of Health, Education And Welfare Method of separating and purifying two active forms of urokinase using affinity chromatography
JPS5396384A (en) * 1977-02-03 1978-08-23 Teijin Ltd Preparation of highly pure urokinase
FR2387242A1 (fr) * 1977-04-12 1978-11-10 Choay Sa Compositions purifiees d'urokinase et procede pour leur obtention
US4245051A (en) * 1978-03-30 1981-01-13 Rockefeller University Human serum plasminogen activator
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
US4278594A (en) * 1979-06-19 1981-07-14 David Amrani Process for separation and isolation of AHF, von Willebrand's ristocetin cofactor (VWF:RCF) and fibronectin from blood plasma
US4210580A (en) * 1979-06-19 1980-07-01 David Amrani Process for separation and isolation of AHF and fibronectin from blood plasma
US4314994A (en) * 1979-07-27 1982-02-09 Pierre Fabre S.A. Process for obtaining a plasminogen activator
CH647548A5 (en) * 1980-02-05 1985-01-31 Pentapharm Ag Process for isolating pure plasminogen-activating proteinases
US4326033A (en) * 1980-05-05 1982-04-20 Abbott Laboratories Modified urokinase having extended activity and method of making
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
US4882275A (en) * 1984-02-29 1989-11-21 The Children's Medical Center Corporation Method of purifying endothelial cell growth factors using immobilized heparin
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
US4661453A (en) * 1984-06-19 1987-04-28 American Biogenetic Sciences, Inc. Production of tissue plasminogen activator factor
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
EP0238551A4 (en) * 1985-09-06 1988-02-01 Codon METHODS OF RECOVERING A TISSUE PLASMINOGEN ACTIVATOR.
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法
US4902782A (en) * 1986-12-10 1990-02-20 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
DE3930359A1 (de) * 1989-09-12 1991-03-28 Bodenseewerk Geraetetech Vorrichtung zur aufhellung von cockpitinstrumenten

Also Published As

Publication number Publication date
ATE49420T1 (de) 1990-01-15
DK161986D0 (da) 1986-04-10
EP0210332B1 (de) 1990-01-10
DE3512910A1 (de) 1986-10-16
JPS61236726A (ja) 1986-10-22
JPH084500B2 (ja) 1996-01-24
NO174111C (no) 1994-03-16
ES553804A0 (es) 1987-02-16
MX167325B (es) 1993-03-16
US5015583A (en) 1991-05-14
DE3668185D1 (de) 1990-02-15
DK161986A (da) 1986-10-12
ES8703522A1 (es) 1987-02-16
IL78452A0 (en) 1986-08-31
NO174111B (no) 1993-12-06
EP0210332A1 (de) 1987-02-04
AU603544B2 (en) 1990-11-22
AU5595286A (en) 1986-11-06
NO861408L (no) 1986-10-13

Similar Documents

Publication Publication Date Title
FR2603581B1 (fr) Procede pour isoler et purifier des aminoacides par chromatographie
DE3865135D1 (de) Fluessigkeitsbehaelter und sein herstellungsverfahren.
DE3564378D1 (en) Pressure swing process for the adsorptive separation of gas mixtures
AU579459B2 (en) Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction
HU906244D0 (en) Process for the production or compounds which eliminate the effect of retrovirus-like proteases and process for the production of medical preparations containing them
FR2554827B1 (fr) Procede d'activation de la bioreactivite des microorganismes
EP0208215A3 (en) Purification of blood clotting factors and other blood proteins on non-carbohydrate sulfated matrices
OA08340A (fr) Procédé de déprotection des esters et éthers allyliques.
IL78452A (en) Process for purification of tissue plasminogen activator (t-pa)
YU45138B (en) Process for the isomerisation of glucose into fructose
YU143583A (en) Process for the isomerisation of glucose into fructose
MA19647A1 (fr) Procede pour isoler ou concentrer des substances aromatiques
NZ224873A (en) Chromatographic purification process for lipopeptide or glycopeptide fermentation products
FR2644474B1 (fr) Procede de purification d'enzymes
ZA862991B (en) Process for the purification of liquid sulphur
EP0260003A3 (en) Process for separating maltose from mixtures of maltose with glucose or other saccharides
EP0307774A3 (en) Process for purifying plasminogen activator
DE3562274D1 (en) Process and apparatus for the pretreatment of liquid sodium containing dissolved impurities
CS206189A2 (en) Enzymatic capillary column for substances concentration selective determination
GB8824632D0 (en) Process for recovery of liquid
GB8825140D0 (en) Process for recovery of liquid
CA803983A (en) Process for the recovery of plasminogen from animal blood serum or animal blood plasma, preferably from pig's blood
PL269587A1 (en) Method for processing liquid carbochemical raws
GB8803324D0 (en) Apparatus for contacting material such as drug with fluid
IE881914L (en) Promoters for the expression of foreign dna in¹methylotrophic bacteria

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees