IL72709A - 7alpha-substituted 3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,process for their production,and pharmaceutical preparations containing same - Google Patents
7alpha-substituted 3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,process for their production,and pharmaceutical preparations containing sameInfo
- Publication number
- IL72709A IL72709A IL72709A IL7270984A IL72709A IL 72709 A IL72709 A IL 72709A IL 72709 A IL72709 A IL 72709A IL 7270984 A IL7270984 A IL 7270984A IL 72709 A IL72709 A IL 72709A
- Authority
- IL
- Israel
- Prior art keywords
- group
- image
- substituted
- carbolactones
- pregn
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/005—3 membered carbocyclic rings in position 12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833330085 DE3330085A1 (de) | 1983-08-17 | 1983-08-17 | 7(alpha)-(1-oxoalkyl)-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
DE19833330086 DE3330086A1 (de) | 1983-08-17 | 1983-08-17 | 7(alpha)-mercapto- und 7(alpha)-alkylthio-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
DE3330084A DE3330084A1 (de) | 1983-08-17 | 1983-08-17 | 7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
Publications (2)
Publication Number | Publication Date |
---|---|
IL72709A0 IL72709A0 (en) | 1984-11-30 |
IL72709A true IL72709A (en) | 1988-08-31 |
Family
ID=27191224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL72709A IL72709A (en) | 1983-08-17 | 1984-08-17 | 7alpha-substituted 3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,process for their production,and pharmaceutical preparations containing same |
Country Status (14)
Country | Link |
---|---|
US (1) | US4559331A (xx) |
EP (2) | EP0134529B1 (xx) |
AT (1) | ATE51233T1 (xx) |
AU (1) | AU578034B2 (xx) |
DD (2) | DD253626A5 (xx) |
DE (1) | DE3481707D1 (xx) |
DK (1) | DK395584A (xx) |
ES (1) | ES8504212A1 (xx) |
FI (1) | FI843208A (xx) |
GR (1) | GR80115B (xx) |
HU (1) | HU193694B (xx) |
IL (1) | IL72709A (xx) |
NO (1) | NO843277L (xx) |
PT (1) | PT79091B (xx) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3414508A1 (de) * | 1984-04-13 | 1985-10-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen |
US4670551A (en) * | 1984-06-21 | 1987-06-02 | Ciba-Geigy Corporation | Epoxy steroids |
US5506222A (en) * | 1991-09-25 | 1996-04-09 | Laboratorios Beta S.A. | Method and composition for treating increased androgenic activity |
ITMI20040367A1 (it) * | 2004-03-01 | 2004-06-01 | Ind Chimica Srl | Processo per la preparazione di drospirenone |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3013012A (en) * | 1960-12-22 | 1961-12-12 | Searle & Co | Alkanoylthio-17alpha-carboxyethyl-17beta-hydroxyandrosten-3-one lactones |
US3509136A (en) * | 1968-07-30 | 1970-04-28 | Searle & Co | 3 - (17beta - hydroxy - 7alpha - (lower alkyl) thio-3-oxoandrost-4-en-17alpha-yl)propionic acid gamma-lactones and congeners |
GB1368006A (en) * | 1972-08-24 | 1974-09-25 | Searle & Co | 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone |
DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
DE2922500A1 (de) * | 1979-05-31 | 1980-12-04 | Schering Ag | 6 beta .7 beta |
EP0043659B1 (en) * | 1980-07-09 | 1985-02-06 | Beecham Group Plc | Clonidine derivatives useful in the treatment of diarrhoea |
DE3111951A1 (de) * | 1981-03-23 | 1982-09-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel |
JPS5921698A (ja) * | 1982-07-22 | 1984-02-03 | シエ−リング・アクチエンゲゼルシヤフト | 17α−プレグネ−4−エン−3−オキソ−21−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬 |
DE3227598A1 (de) * | 1982-07-22 | 1984-01-26 | Schering AG, 1000 Berlin und 4709 Bergkamen | 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel |
JPS59139400A (ja) * | 1983-01-31 | 1984-08-10 | Shionogi & Co Ltd | 抗アルドステロン活性ステロイド誘導体 |
-
1984
- 1984-07-26 AT AT84108845T patent/ATE51233T1/de not_active IP Right Cessation
- 1984-07-26 EP EP84108845A patent/EP0134529B1/de not_active Expired - Lifetime
- 1984-07-26 DE DE8484108845T patent/DE3481707D1/de not_active Expired - Lifetime
- 1984-08-14 GR GR80115A patent/GR80115B/el unknown
- 1984-08-14 FI FI843208A patent/FI843208A/fi not_active Application Discontinuation
- 1984-08-15 DD DD84266308A patent/DD253626A5/de unknown
- 1984-08-15 DD DD84285918A patent/DD242410C4/de unknown
- 1984-08-16 HU HU843108A patent/HU193694B/hu unknown
- 1984-08-16 AU AU32001/84A patent/AU578034B2/en not_active Ceased
- 1984-08-16 PT PT79091A patent/PT79091B/pt unknown
- 1984-08-16 NO NO843277A patent/NO843277L/no unknown
- 1984-08-16 ES ES535187A patent/ES8504212A1/es not_active Expired
- 1984-08-17 IL IL72709A patent/IL72709A/xx unknown
- 1984-08-17 DK DK395584A patent/DK395584A/da not_active Application Discontinuation
- 1984-08-17 US US06/641,599 patent/US4559331A/en not_active Expired - Fee Related
-
1988
- 1988-10-17 EP EP88730228A patent/EP0308365A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
PT79091B (de) | 1986-08-14 |
IL72709A0 (en) | 1984-11-30 |
DK395584A (da) | 1985-02-18 |
DD242410C4 (de) | 1987-11-11 |
EP0134529B1 (de) | 1990-03-21 |
DD242410A5 (de) | 1987-01-28 |
EP0134529A2 (de) | 1985-03-20 |
EP0134529A3 (en) | 1985-08-21 |
DE3481707D1 (de) | 1990-04-26 |
ATE51233T1 (de) | 1990-04-15 |
AU3200184A (en) | 1985-02-21 |
FI843208A0 (fi) | 1984-08-14 |
ES535187A0 (es) | 1985-05-01 |
DK395584D0 (da) | 1984-08-17 |
NO843277L (no) | 1985-02-18 |
AU578034B2 (en) | 1988-10-13 |
GR80115B (en) | 1984-12-14 |
PT79091A (de) | 1984-09-01 |
EP0308365A1 (de) | 1989-03-22 |
HUT34995A (en) | 1985-05-28 |
ES8504212A1 (es) | 1985-05-01 |
FI843208A (fi) | 1985-02-18 |
US4559331A (en) | 1985-12-17 |
DD253626A5 (de) | 1988-01-27 |
HU193694B (en) | 1987-11-30 |
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