ES535187A0 - Procedimiento para la preparacion de 3-oxo-170-pregn-4-en-21,17. carbolactonas sustituidas en 7a - Google Patents

Procedimiento para la preparacion de 3-oxo-170-pregn-4-en-21,17. carbolactonas sustituidas en 7a

Info

Publication number
ES535187A0
ES535187A0 ES535187A ES535187A ES535187A0 ES 535187 A0 ES535187 A0 ES 535187A0 ES 535187 A ES535187 A ES 535187A ES 535187 A ES535187 A ES 535187A ES 535187 A0 ES535187 A0 ES 535187A0
Authority
ES
Spain
Prior art keywords
group
image
substituted
carbolactones
pregn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES535187A
Other languages
English (en)
Other versions
ES8504212A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19833330085 external-priority patent/DE3330085A1/de
Priority claimed from DE3330084A external-priority patent/DE3330084A1/de
Priority claimed from DE19833330086 external-priority patent/DE3330086A1/de
Application filed by Schering AG filed Critical Schering AG
Publication of ES535187A0 publication Critical patent/ES535187A0/es
Publication of ES8504212A1 publication Critical patent/ES8504212A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/005—3 membered carbocyclic rings in position 12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
ES535187A 1983-08-17 1984-08-16 Procedimiento para la preparacion de 3-oxo-170-pregn-4-en-21,17. carbolactonas sustituidas en 7a Expired ES8504212A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19833330085 DE3330085A1 (de) 1983-08-17 1983-08-17 7(alpha)-(1-oxoalkyl)-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3330084A DE3330084A1 (de) 1983-08-17 1983-08-17 7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE19833330086 DE3330086A1 (de) 1983-08-17 1983-08-17 7(alpha)-mercapto- und 7(alpha)-alkylthio-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate

Publications (2)

Publication Number Publication Date
ES535187A0 true ES535187A0 (es) 1985-05-01
ES8504212A1 ES8504212A1 (es) 1985-05-01

Family

ID=27191224

Family Applications (1)

Application Number Title Priority Date Filing Date
ES535187A Expired ES8504212A1 (es) 1983-08-17 1984-08-16 Procedimiento para la preparacion de 3-oxo-170-pregn-4-en-21,17. carbolactonas sustituidas en 7a

Country Status (14)

Country Link
US (1) US4559331A (es)
EP (2) EP0134529B1 (es)
AT (1) ATE51233T1 (es)
AU (1) AU578034B2 (es)
DD (2) DD253626A5 (es)
DE (1) DE3481707D1 (es)
DK (1) DK395584A (es)
ES (1) ES8504212A1 (es)
FI (1) FI843208A (es)
GR (1) GR80115B (es)
HU (1) HU193694B (es)
IL (1) IL72709A (es)
NO (1) NO843277L (es)
PT (1) PT79091B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3414508A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrfach tritiierte steroid-20.17-spirolactone und ihre verwendung als tracersubstanzen
US4670551A (en) * 1984-06-21 1987-06-02 Ciba-Geigy Corporation Epoxy steroids
US5506222A (en) * 1991-09-25 1996-04-09 Laboratorios Beta S.A. Method and composition for treating increased androgenic activity
ITMI20040367A1 (it) * 2004-03-01 2004-06-01 Ind Chimica Srl Processo per la preparazione di drospirenone

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013012A (en) * 1960-12-22 1961-12-12 Searle & Co Alkanoylthio-17alpha-carboxyethyl-17beta-hydroxyandrosten-3-one lactones
US3509136A (en) * 1968-07-30 1970-04-28 Searle & Co 3 - (17beta - hydroxy - 7alpha - (lower alkyl) thio-3-oxoandrost-4-en-17alpha-yl)propionic acid gamma-lactones and congeners
GB1368006A (en) * 1972-08-24 1974-09-25 Searle & Co 4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2922500A1 (de) * 1979-05-31 1980-12-04 Schering Ag 6 beta .7 beta
DE3168754D1 (en) * 1980-07-09 1985-03-21 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea
DE3111951A1 (de) * 1981-03-23 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3227598A1 (de) * 1982-07-22 1984-01-26 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
JPS59139400A (ja) * 1983-01-31 1984-08-10 Shionogi & Co Ltd 抗アルドステロン活性ステロイド誘導体

Also Published As

Publication number Publication date
IL72709A0 (en) 1984-11-30
DK395584D0 (da) 1984-08-17
AU578034B2 (en) 1988-10-13
ATE51233T1 (de) 1990-04-15
PT79091B (de) 1986-08-14
DK395584A (da) 1985-02-18
EP0134529B1 (de) 1990-03-21
DD242410A5 (de) 1987-01-28
GR80115B (en) 1984-12-14
FI843208A0 (fi) 1984-08-14
US4559331A (en) 1985-12-17
HUT34995A (en) 1985-05-28
EP0308365A1 (de) 1989-03-22
IL72709A (en) 1988-08-31
EP0134529A3 (en) 1985-08-21
PT79091A (de) 1984-09-01
HU193694B (en) 1987-11-30
ES8504212A1 (es) 1985-05-01
EP0134529A2 (de) 1985-03-20
DD253626A5 (de) 1988-01-27
DD242410C4 (de) 1987-11-11
NO843277L (no) 1985-02-18
AU3200184A (en) 1985-02-21
DE3481707D1 (de) 1990-04-26
FI843208A (fi) 1985-02-18

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