IL72417A - Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them - Google Patents

Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72417A
IL72417A IL72417A IL7241784A IL72417A IL 72417 A IL72417 A IL 72417A IL 72417 A IL72417 A IL 72417A IL 7241784 A IL7241784 A IL 7241784A IL 72417 A IL72417 A IL 72417A
Authority
IL
Israel
Prior art keywords
group
substituted
alkyl
phenylimidazole
pharmaceutical compositions
Prior art date
Application number
IL72417A
Other languages
English (en)
Other versions
IL72417A0 (en
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of IL72417A0 publication Critical patent/IL72417A0/xx
Publication of IL72417A publication Critical patent/IL72417A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Treatment Of Sludge (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL72417A 1983-07-18 1984-07-16 Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them IL72417A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Publications (2)

Publication Number Publication Date
IL72417A0 IL72417A0 (en) 1984-11-30
IL72417A true IL72417A (en) 1988-03-31

Family

ID=11191639

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72417A IL72417A (en) 1983-07-18 1984-07-16 Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (1) US4649150A (de)
EP (1) EP0131973B1 (de)
JP (1) JPS6038367A (de)
KR (1) KR910000661B1 (de)
AT (1) ATE45149T1 (de)
AU (1) AU565292B2 (de)
CA (1) CA1257274A (de)
CS (1) CS244141B2 (de)
DD (1) DD232696A5 (de)
DE (1) DE3479212D1 (de)
DK (1) DK350084A (de)
ES (2) ES8601910A1 (de)
FI (1) FI842432A7 (de)
GB (1) GB2149395B (de)
GR (1) GR79981B (de)
HK (1) HK74287A (de)
HU (1) HU193292B (de)
IL (1) IL72417A (de)
IT (1) IT1206498B (de)
NO (1) NO162857C (de)
NZ (1) NZ208920A (de)
PH (1) PH21566A (de)
PL (2) PL143732B1 (de)
PT (1) PT78935B (de)
SG (1) SG48687G (de)
SU (2) SU1322979A3 (de)
YU (2) YU43367B (de)
ZA (1) ZA845490B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
IL133731A0 (en) 1997-07-03 2001-04-30 Neurogen Corp Certain diarylimidazole derivatives, a new class of npy specific ligands
US6887870B1 (en) 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
SK8452002A3 (en) 1999-12-16 2002-11-06 Schering Corp Substituted 4-(phenyl or pyridyl)imidazole derivatives, pharmaceutical composition comprising the same and use thereof
FR2917087B1 (fr) 2007-06-05 2012-09-21 Galderma Res & Dev Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.

Also Published As

Publication number Publication date
KR850001173A (ko) 1985-03-16
GB2149395A (en) 1985-06-12
DK350084D0 (da) 1984-07-17
PT78935A (de) 1984-08-01
NO842921L (no) 1985-01-21
ES8505962A1 (es) 1985-06-16
EP0131973B1 (de) 1989-08-02
NO162857B (no) 1989-11-20
PL143303B1 (en) 1988-02-29
IL72417A0 (en) 1984-11-30
YU43367B (en) 1989-06-30
DK350084A (da) 1985-01-19
GR79981B (de) 1984-10-31
NO162857C (no) 1990-02-28
ES534375A0 (es) 1985-06-16
ES534376A0 (es) 1985-11-01
DE3479212D1 (en) 1989-09-07
CS554284A2 (en) 1985-08-15
YU112686A (en) 1987-12-31
SG48687G (en) 1987-07-24
FI842432A0 (fi) 1984-06-15
ES8601910A1 (es) 1985-11-01
GB8418149D0 (en) 1984-08-22
IT1206498B (it) 1989-04-27
CA1257274A (en) 1989-07-11
JPS6038367A (ja) 1985-02-27
CS244141B2 (en) 1986-07-17
PL143732B1 (en) 1988-03-31
HU193292B (en) 1987-09-28
PL248779A1 (en) 1985-12-03
AU3080084A (en) 1985-01-24
HUT34959A (en) 1985-05-28
YU43701B (en) 1989-10-31
US4649150A (en) 1987-03-10
SU1322979A3 (ru) 1987-07-07
HK74287A (en) 1987-10-23
AU565292B2 (en) 1987-09-10
IT8322110A0 (it) 1983-07-18
GB2149395B (en) 1986-11-26
PH21566A (en) 1987-12-11
NZ208920A (en) 1987-03-31
KR910000661B1 (ko) 1991-01-31
PT78935B (de) 1986-10-23
EP0131973A1 (de) 1985-01-23
FI842432A7 (fi) 1985-01-19
SU1313345A3 (ru) 1987-05-23
ZA845490B (en) 1986-03-26
DD232696A5 (de) 1986-02-05
ATE45149T1 (de) 1989-08-15
PL254625A1 (en) 1986-05-06
YU115484A (en) 1986-12-31

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