IL67378A - Process for the separation of mixtures of insulin,insulin derivatives and,where appropriate,impurities - Google Patents

Process for the separation of mixtures of insulin,insulin derivatives and,where appropriate,impurities

Info

Publication number
IL67378A
IL67378A IL67378A IL6737882A IL67378A IL 67378 A IL67378 A IL 67378A IL 67378 A IL67378 A IL 67378A IL 6737882 A IL6737882 A IL 6737882A IL 67378 A IL67378 A IL 67378A
Authority
IL
Israel
Prior art keywords
insulin
impurities
mixtures
separation
appropriate
Prior art date
Application number
IL67378A
Other languages
English (en)
Other versions
IL67378A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL67378A0 publication Critical patent/IL67378A0/xx
Publication of IL67378A publication Critical patent/IL67378A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL67378A 1981-12-03 1982-12-01 Process for the separation of mixtures of insulin,insulin derivatives and,where appropriate,impurities IL67378A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813147842 DE3147842A1 (de) 1981-12-03 1981-12-03 "verfahren zur trennung von gemischen aus insulin, insulinderivaten und gegebenenfalls verunreinigungen"

Publications (2)

Publication Number Publication Date
IL67378A0 IL67378A0 (en) 1983-05-15
IL67378A true IL67378A (en) 1985-12-31

Family

ID=6147790

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67378A IL67378A (en) 1981-12-03 1982-12-01 Process for the separation of mixtures of insulin,insulin derivatives and,where appropriate,impurities

Country Status (15)

Country Link
US (1) US4677192A (da)
EP (1) EP0082359B1 (da)
JP (1) JPS58103323A (da)
KR (1) KR880002607B1 (da)
AR (1) AR230430A1 (da)
AT (1) ATE18057T1 (da)
AU (1) AU563350B2 (da)
CA (1) CA1245633A (da)
DE (2) DE3147842A1 (da)
DK (1) DK162104C (da)
ES (1) ES8607343A1 (da)
FI (1) FI75349C (da)
GR (1) GR77764B (da)
IL (1) IL67378A (da)
ZA (1) ZA828864B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3511269A1 (de) * 1985-04-12 1986-10-09 Veb Berlin-Chemie, Ddr 1199 Berlin Verfahren zur reinigung von insulin
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
US5278284A (en) * 1992-05-14 1994-01-11 Miller Brewing Company Protein purification method
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
WO2016014325A1 (en) 2014-07-21 2016-01-28 Merck Sharp & Dohme Corp. Chromatography process for purification of inlsulin and insulin analogs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532492A (en) * 1976-06-26 1978-01-11 Shimizu Seiyaku Kk Process for preparing pure insuline
JPS5542185A (en) * 1978-09-22 1980-03-25 Kawasaki Heavy Ind Ltd Detecting device for arc welding or the like
JPS6016673B2 (ja) * 1978-12-25 1985-04-26 川崎重工業株式会社 サ−ボ系における被検体認識装置

Also Published As

Publication number Publication date
JPS58103323A (ja) 1983-06-20
IL67378A0 (en) 1983-05-15
AU563350B2 (en) 1987-07-09
FI824135L (fi) 1983-06-04
EP0082359B1 (de) 1986-02-19
KR880002607B1 (ko) 1988-12-04
AR230430A1 (es) 1984-04-30
DE3147842A1 (de) 1983-06-23
DK162104B (da) 1991-09-16
DK536282A (da) 1983-06-04
ZA828864B (en) 1984-05-30
EP0082359A1 (de) 1983-06-29
FI75349B (fi) 1988-02-29
ATE18057T1 (de) 1986-03-15
AU9110282A (en) 1983-06-09
ES8607343A1 (es) 1986-05-16
US4677192A (en) 1987-06-30
GR77764B (da) 1984-09-25
KR840002771A (ko) 1984-07-16
DE3269252D1 (en) 1986-03-27
DK162104C (da) 1992-02-17
JPH0354678B2 (da) 1991-08-20
ES517844A0 (es) 1986-05-16
FI75349C (fi) 1988-06-09
CA1245633A (en) 1988-11-29
FI824135A0 (fi) 1982-12-01

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Legal Events

Date Code Title Description
RH Patent void