DK162104C - Fremgangsmaade til chromatografisk adskillelse af blandinger af insulin, insulinderivater og eventuelt urenheder - Google Patents

Fremgangsmaade til chromatografisk adskillelse af blandinger af insulin, insulinderivater og eventuelt urenheder

Info

Publication number
DK162104C
DK162104C DK536282A DK536282A DK162104C DK 162104 C DK162104 C DK 162104C DK 536282 A DK536282 A DK 536282A DK 536282 A DK536282 A DK 536282A DK 162104 C DK162104 C DK 162104C
Authority
DK
Denmark
Prior art keywords
insulin
mixtures
procedure
purposes
chromatographic separation
Prior art date
Application number
DK536282A
Other languages
English (en)
Other versions
DK162104B (da
DK536282A (da
Inventor
Rainer Obermeier
Volker Teetz
Juergen Ludwig
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK536282A publication Critical patent/DK536282A/da
Publication of DK162104B publication Critical patent/DK162104B/da
Application granted granted Critical
Publication of DK162104C publication Critical patent/DK162104C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • C07K14/625Extraction from natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK536282A 1981-12-03 1982-12-02 Fremgangsmaade til chromatografisk adskillelse af blandinger af insulin, insulinderivater og eventuelt urenheder DK162104C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813147842 DE3147842A1 (de) 1981-12-03 1981-12-03 "verfahren zur trennung von gemischen aus insulin, insulinderivaten und gegebenenfalls verunreinigungen"
DE3147842 1981-12-03

Publications (3)

Publication Number Publication Date
DK536282A DK536282A (da) 1983-06-04
DK162104B DK162104B (da) 1991-09-16
DK162104C true DK162104C (da) 1992-02-17

Family

ID=6147790

Family Applications (1)

Application Number Title Priority Date Filing Date
DK536282A DK162104C (da) 1981-12-03 1982-12-02 Fremgangsmaade til chromatografisk adskillelse af blandinger af insulin, insulinderivater og eventuelt urenheder

Country Status (15)

Country Link
US (1) US4677192A (da)
EP (1) EP0082359B1 (da)
JP (1) JPS58103323A (da)
KR (1) KR880002607B1 (da)
AR (1) AR230430A1 (da)
AT (1) ATE18057T1 (da)
AU (1) AU563350B2 (da)
CA (1) CA1245633A (da)
DE (2) DE3147842A1 (da)
DK (1) DK162104C (da)
ES (1) ES8607343A1 (da)
FI (1) FI75349C (da)
GR (1) GR77764B (da)
IL (1) IL67378A (da)
ZA (1) ZA828864B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3511269A1 (de) * 1985-04-12 1986-10-09 Veb Berlin-Chemie, Ddr 1199 Berlin Verfahren zur reinigung von insulin
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
US5278284A (en) * 1992-05-14 1994-01-11 Miller Brewing Company Protein purification method
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
WO2016014325A1 (en) 2014-07-21 2016-01-28 Merck Sharp & Dohme Corp. Chromatography process for purification of inlsulin and insulin analogs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532492A (en) * 1976-06-26 1978-01-11 Shimizu Seiyaku Kk Process for preparing pure insuline
JPS5542185A (en) * 1978-09-22 1980-03-25 Kawasaki Heavy Ind Ltd Detecting device for arc welding or the like
JPS6016673B2 (ja) * 1978-12-25 1985-04-26 川崎重工業株式会社 サ−ボ系における被検体認識装置

Also Published As

Publication number Publication date
JPS58103323A (ja) 1983-06-20
IL67378A0 (en) 1983-05-15
AU563350B2 (en) 1987-07-09
FI824135L (fi) 1983-06-04
EP0082359B1 (de) 1986-02-19
KR880002607B1 (ko) 1988-12-04
AR230430A1 (es) 1984-04-30
DE3147842A1 (de) 1983-06-23
DK162104B (da) 1991-09-16
DK536282A (da) 1983-06-04
ZA828864B (en) 1984-05-30
EP0082359A1 (de) 1983-06-29
FI75349B (fi) 1988-02-29
ATE18057T1 (de) 1986-03-15
AU9110282A (en) 1983-06-09
ES8607343A1 (es) 1986-05-16
US4677192A (en) 1987-06-30
GR77764B (da) 1984-09-25
KR840002771A (ko) 1984-07-16
DE3269252D1 (en) 1986-03-27
JPH0354678B2 (da) 1991-08-20
ES517844A0 (es) 1986-05-16
IL67378A (en) 1985-12-31
FI75349C (fi) 1988-06-09
CA1245633A (en) 1988-11-29
FI824135A0 (fi) 1982-12-01

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PBP Patent lapsed