IL60422A - Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them - Google Patents
Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL60422A IL60422A IL60422A IL6042280A IL60422A IL 60422 A IL60422 A IL 60422A IL 60422 A IL60422 A IL 60422A IL 6042280 A IL6042280 A IL 6042280A IL 60422 A IL60422 A IL 60422A
- Authority
- IL
- Israel
- Prior art keywords
- formylhydroxyphenoxy
- pentanoic
- derivatives
- preparation
- pharmaceutical compositions
- Prior art date
Links
- ZWLPBLYKEWSWPD-UHFFFAOYSA-N o-toluic acid Chemical class CC1=CC=CC=C1C(O)=O ZWLPBLYKEWSWPD-UHFFFAOYSA-N 0.000 title 1
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N pentanoic acid group Chemical group C(CCCC)(=O)O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/74—Unsaturated compounds containing —CHO groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7922781 | 1979-06-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL60422A0 IL60422A0 (en) | 1980-09-16 |
| IL60422A true IL60422A (en) | 1984-06-29 |
Family
ID=10506199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL60422A IL60422A (en) | 1979-06-29 | 1980-06-27 | Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4410537A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0022229B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS5649335A (cg-RX-API-DMAC7.html) |
| KR (2) | KR850000073B1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU545274B2 (cg-RX-API-DMAC7.html) |
| DE (1) | DE3061269D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK159770C (cg-RX-API-DMAC7.html) |
| FI (1) | FI71929C (cg-RX-API-DMAC7.html) |
| GB (1) | GB2053218B (cg-RX-API-DMAC7.html) |
| GR (1) | GR68748B (cg-RX-API-DMAC7.html) |
| HU (1) | HU190774B (cg-RX-API-DMAC7.html) |
| IL (1) | IL60422A (cg-RX-API-DMAC7.html) |
| IT (1) | IT1133025B (cg-RX-API-DMAC7.html) |
| MW (1) | MW2380A1 (cg-RX-API-DMAC7.html) |
| OA (1) | OA06699A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA803880B (cg-RX-API-DMAC7.html) |
| ZM (1) | ZM5780A1 (cg-RX-API-DMAC7.html) |
| ZW (1) | ZW14480A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190371B (en) * | 1980-12-18 | 1986-08-28 | The Wellcome Foundation Ltd,Gb | Process for producing ether-type compounds and pharmaceutical compositions containing them as active agents |
| GB8606913D0 (en) * | 1986-03-20 | 1986-04-23 | Hider R C | Treatment of sickle cell disease |
| AU6019898A (en) | 1997-01-09 | 1998-08-03 | Cohesion Technologies, Inc. | Devices for tissue repair and methods for preparation and use thereof |
| RU2300516C2 (ru) * | 1999-11-05 | 2007-06-10 | Эмисфере Текнолоджиз, Инк. | Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ |
| US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| JP2004501057A (ja) * | 1999-11-05 | 2004-01-15 | エミスフェアー・テクノロジーズ・インク | フェニルアミンカルボン酸化合物及び活性剤を送達するための組成物 |
| US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| CA2403553A1 (en) * | 2000-03-17 | 2001-09-27 | David Johnson | Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors |
| US8246969B2 (en) | 2001-11-16 | 2012-08-21 | Skinmedica, Inc. | Compositions containing aromatic aldehydes and their use in treatments |
| KR101916489B1 (ko) | 2011-01-07 | 2018-11-07 | 알러간, 인코포레이티드 | 멜라닌 변형 조성물들 및 이의 사용 방법들 |
| ES2790358T3 (es) * | 2011-12-28 | 2020-10-27 | Global Blood Therapeutics Inc | Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular |
| SI3738434T1 (sl) | 2011-12-28 | 2024-01-31 | Global Blood Therapeutics, Inc. | Vmesne spojine za pridobivanje substituiranih benzaldehidnih spojin in postopki njihove uporabe pri povečanju oksigenacije tkiv |
| US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| SG11201507453VA (en) | 2013-03-15 | 2015-10-29 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
| US9422279B2 (en) | 2013-03-15 | 2016-08-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US20140274961A1 (en) | 2013-03-15 | 2014-09-18 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10266551B2 (en) | 2013-03-15 | 2019-04-23 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| EP2970196B1 (en) * | 2013-03-15 | 2020-11-25 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US10100043B2 (en) | 2013-03-15 | 2018-10-16 | Global Blood Therapeutics, Inc. | Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation |
| US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9802900B2 (en) | 2013-03-15 | 2017-10-31 | Global Blood Therapeutics, Inc. | Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin |
| US9981939B2 (en) | 2013-03-15 | 2018-05-29 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| US9604999B2 (en) | 2013-03-15 | 2017-03-28 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
| WO2015027067A2 (en) * | 2013-08-23 | 2015-02-26 | Virginia Commonwealth University | Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease |
| EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
| DK3102208T4 (da) | 2014-02-07 | 2024-08-26 | Global Blood Therapeutics Inc | Krystallinsk polymorph af den frie base af 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyd |
| CA2978567A1 (en) | 2015-03-06 | 2016-09-15 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a ras mutation using plinabulin |
| MA41841A (fr) | 2015-03-30 | 2018-02-06 | Global Blood Therapeutics Inc | Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs |
| ES3039236T3 (en) | 2015-12-04 | 2025-10-20 | Global Blood Therapeutics Inc | Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
| US10912748B2 (en) * | 2016-02-08 | 2021-02-09 | Beyondspring Pharmaceuticals, Inc. | Compositions containing tucaresol or its analogs |
| TWI663160B (zh) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
| SG11201810872UA (en) | 2016-06-06 | 2019-01-30 | Beyondspring Pharmaceuticals Inc | Composition and method for reducing neutropenia |
| TW202332423A (zh) | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
| JP2020503363A (ja) | 2017-01-06 | 2020-01-30 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | チューブリン結合化合物およびその治療的使用 |
| CN110381938A (zh) | 2017-02-01 | 2019-10-25 | 大连万春布林医药有限公司 | 减少中性粒细胞缺乏症的方法 |
| US11401241B2 (en) * | 2018-03-22 | 2022-08-02 | Virginia Commonwealth University | Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease |
| US11014884B2 (en) | 2018-10-01 | 2021-05-25 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin |
| KR102842589B1 (ko) | 2018-11-19 | 2025-08-04 | 글로벌 블러드 테라퓨틱스, 인크. | 헤모글로빈을 조정할 수 있는 2-포르밀-3-히드록시페닐옥시메틸 화합물 |
| WO2020163689A1 (en) | 2019-02-08 | 2020-08-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | 20-hete formation inhibitors |
| EP4319751A4 (en) | 2021-04-09 | 2025-02-26 | Beyondspring Pharmaceuticals, Inc. | THERAPEUTIC COMPOSITIONS AND METHODS FOR THE TREATING OF TUMORS |
| IL320636A (en) * | 2022-11-07 | 2025-07-01 | Univ Virginia Commonwealth | Benzaldehyde compounds with destabilizing effects on polymers for the treatment of sickle cell disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL105100C (cg-RX-API-DMAC7.html) * | 1958-04-30 | |||
| CH543472A (fr) * | 1969-01-31 | 1973-10-31 | Orchimed Sa | Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques |
| CH550776A (de) | 1971-03-05 | 1974-06-28 | Ciba Geigy Ag | Herstellung neuer bis-stilbenverbindungen. |
| DE2209128C3 (de) | 1971-03-05 | 1981-10-22 | CIBA-GEIGY AG, 4002 Basel | Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller |
| GB1511645A (en) | 1974-05-31 | 1978-05-24 | Univ Ife | Sickle cell anaemia treatment |
| US4137309A (en) * | 1976-10-14 | 1979-01-30 | The Procter & Gamble Company | Therapeutic treatment |
-
1980
- 1980-06-27 ZA ZA00803880A patent/ZA803880B/xx unknown
- 1980-06-27 MW MW23/80A patent/MW2380A1/xx unknown
- 1980-06-27 IT IT49108/80A patent/IT1133025B/it active
- 1980-06-27 KR KR1019800002541A patent/KR850000073B1/ko not_active Expired
- 1980-06-27 DE DE8080103657T patent/DE3061269D1/de not_active Expired
- 1980-06-27 JP JP8764580A patent/JPS5649335A/ja active Granted
- 1980-06-27 DK DK279780A patent/DK159770C/da not_active IP Right Cessation
- 1980-06-27 EP EP80103657A patent/EP0022229B1/en not_active Expired
- 1980-06-27 FI FI802052A patent/FI71929C/fi not_active IP Right Cessation
- 1980-06-27 GB GB8021219A patent/GB2053218B/en not_active Expired
- 1980-06-27 IL IL60422A patent/IL60422A/xx not_active IP Right Cessation
- 1980-06-27 GR GR62311A patent/GR68748B/el unknown
- 1980-06-27 ZW ZW144/80A patent/ZW14480A1/xx unknown
- 1980-06-27 HU HU801601A patent/HU190774B/hu not_active IP Right Cessation
- 1980-06-27 AU AU59697/80A patent/AU545274B2/en not_active Ceased
- 1980-06-27 ZM ZM57/80A patent/ZM5780A1/xx unknown
- 1980-08-09 OA OA57193A patent/OA06699A/xx unknown
-
1981
- 1981-06-09 US US06/271,950 patent/US4410537A/en not_active Expired - Lifetime
-
1984
- 1984-03-13 KR KR1019840001263A patent/KR850000072B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZW14480A1 (en) | 1982-03-17 |
| KR850000073B1 (ko) | 1985-02-18 |
| EP0022229A1 (en) | 1981-01-14 |
| KR840004668A (ko) | 1984-10-22 |
| JPH0154339B2 (cg-RX-API-DMAC7.html) | 1989-11-17 |
| IL60422A0 (en) | 1980-09-16 |
| ZA803880B (en) | 1982-02-24 |
| GB2053218A (en) | 1981-02-04 |
| ZM5780A1 (en) | 1983-11-21 |
| US4410537A (en) | 1983-10-18 |
| KR830002693A (ko) | 1983-05-30 |
| HU190774B (en) | 1986-11-28 |
| GB2053218B (en) | 1984-01-25 |
| MW2380A1 (en) | 1982-03-10 |
| GR68748B (cg-RX-API-DMAC7.html) | 1982-02-16 |
| FI802052A7 (fi) | 1980-12-30 |
| FI71929C (fi) | 1987-03-09 |
| FI71929B (fi) | 1986-11-28 |
| DK279780A (da) | 1980-12-30 |
| DE3061269D1 (en) | 1983-01-13 |
| KR850000072B1 (ko) | 1985-02-18 |
| AU5969780A (en) | 1981-01-08 |
| DK159770B (da) | 1990-12-03 |
| JPS5649335A (en) | 1981-05-02 |
| IT1133025B (it) | 1986-07-09 |
| OA06699A (fr) | 1982-05-31 |
| IT8049108A0 (it) | 1980-06-27 |
| DK159770C (da) | 1991-04-22 |
| AU545274B2 (en) | 1985-07-11 |
| EP0022229B1 (en) | 1982-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL60422A (en) | Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them | |
| IL61307A0 (en) | Derivatives of 6 -hydroxyalkylpenicillanic acids, their preparation and pharmaceutical compositions containing them | |
| IL58978A0 (en) | Peptidyl-arginne aldehyde derivatives their preparation and pharmaceutical compositions containing them | |
| IL57708A0 (en) | Aminopropoxyindole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL56991A (en) | 4-halo-3-oxoandrost-4-ene-17 beta-thiocarboxylic acid esters,their preparation and pharmaceutical compositions containing them | |
| MY8700186A (en) | 3-aminopropoxyaryl derivatives their preparation and pharmaceutical compositions containing them | |
| IL56421A0 (en) | 4-pyridone-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| IL57297A0 (en) | 4-amino-2-piperidinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
| DE3065460D1 (en) | Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| NZ194784A (en) | 7 -aminothiadizolylacetylamino-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions | |
| IL58229A0 (en) | Aurone derivatives their preparation and pharmaceutical compositions containing them | |
| IL56856A (en) | 4,5-diaryl-pyrrole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL58620A0 (en) | Aryltrifluoroethanol derivatives their preparation and pharmaceutical compositions containing them | |
| IL56816A0 (en) | N-phenylaniline derivatives,their preparation and pharmaceutical compositions containing them | |
| IL55152A0 (en) | 7-acylamido-3-cephem-4-carboxylic acids and esters and salts thereof,their preparation and pharmaceutical compositions containing them | |
| IL56913A (en) | Sprio-steroid-oxazolidinone derivatives,their preparation and pharmaceutical compositions containing them | |
| IL56890A0 (en) | 2-amino-carbazole derivatives,their preparation and pharmaceutical compositions containing them | |
| IL61675A0 (en) | N-substituted -amino acids and derivatives thereof,their preparation and pharmaceutical compositions containing them | |
| DE2963868D1 (en) | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | |
| IL56461A0 (en) | 1-naphthyl-acetic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| IL57735A (en) | 7beta-aminothiazolyl-acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL56349A0 (en) | 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them | |
| NZ194122A (en) | Acylaminobenzoic acid derivatives and pharmaceutical compositions | |
| IL58169A0 (en) | -alkyl-o-oxybenzylamine derivatives their preparation and pharmaceutical compositions containing them | |
| IL60513A (en) | Dihydronicotinic acid derivatives,their preparation and pharmaceutical compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |