IL58490A - Derivatives of polyene macrolide antibiotics containing an amino sugar moiety,process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Derivatives of polyene macrolide antibiotics containing an amino sugar moiety,process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
IL58490A
IL58490A IL58490A IL5849079A IL58490A IL 58490 A IL58490 A IL 58490A IL 58490 A IL58490 A IL 58490A IL 5849079 A IL5849079 A IL 5849079A IL 58490 A IL58490 A IL 58490A
Authority
IL
Israel
Prior art keywords
hydrogen
zero
polyene macrolide
compounds
phenylpropargyl
Prior art date
Application number
IL58490A
Other languages
English (en)
Other versions
IL58490A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL58490A0 publication Critical patent/IL58490A0/xx
Publication of IL58490A publication Critical patent/IL58490A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
IL58490A 1978-10-23 1979-10-18 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety,process for the preparation thereof and pharmaceutical compositions containing them IL58490A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95382478A 1978-10-23 1978-10-23

Publications (2)

Publication Number Publication Date
IL58490A0 IL58490A0 (en) 1980-01-31
IL58490A true IL58490A (en) 1983-07-31

Family

ID=25494578

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58490A IL58490A (en) 1978-10-23 1979-10-18 Derivatives of polyene macrolide antibiotics containing an amino sugar moiety,process for the preparation thereof and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0010297B1 (no)
JP (1) JPS5557600A (no)
AT (1) ATE3046T1 (no)
AU (1) AU5190079A (no)
CA (1) CA1132542A (no)
DE (1) DE2965212D1 (no)
DK (1) DK439879A (no)
FI (1) FI793236A (no)
GR (1) GR74128B (no)
HU (1) HU181506B (no)
IL (1) IL58490A (no)
NO (1) NO147840C (no)
PT (1) PT70341A (no)
ZA (1) ZA795508B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104326A (ja) * 1982-12-04 1984-06-16 Toyo Jozo Co Ltd マクロライド抗生物質の安定な経口用製剤および安定化法
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention
MX9706283A (es) * 1996-08-19 1998-02-28 Hoechst Ag Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo.
US6346610B1 (en) * 1997-06-03 2002-02-12 Ajinomoto Co., Ltd. Process for preparing antifungal V-28-3M
US5981721A (en) * 1997-10-23 1999-11-09 Karykion Corporation Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof
JP2010534688A (ja) * 2007-07-30 2010-11-11 上海医薬工業研究院 ポリエン類抗生物質ジエステル化合物
CN113166188B (zh) * 2018-12-13 2023-06-20 正大天晴药业集团股份有限公司 两性霉素b肽衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244590A (en) * 1960-12-23 1966-04-05 Rutgers Res And Educational Fo Polyenic compounds and procedures related thereto
US4038382A (en) 1972-07-24 1977-07-26 Spa-Societe Prodotti Antibiotici S.P.A. Alkyl esters of polyene antibiotics
GB1399139A (en) 1972-07-24 1975-06-25 Prodotti Antibiotici Spa Alkyl esters of polyene antibiotics
US4041232A (en) * 1976-02-23 1977-08-09 E. R. Squibb & Sons, Inc. Amphotericin B methyl ester salts

Also Published As

Publication number Publication date
HU181506B (en) 1983-10-28
GR74128B (no) 1984-06-06
EP0010297B1 (en) 1983-04-13
NO147840C (no) 1983-06-22
IL58490A0 (en) 1980-01-31
EP0010297A1 (en) 1980-04-30
AU5190079A (en) 1980-05-01
DE2965212D1 (en) 1983-05-19
ZA795508B (en) 1981-05-27
NO147840B (no) 1983-03-14
NO793354L (no) 1980-04-24
JPS5557600A (en) 1980-04-28
PT70341A (en) 1979-11-01
FI793236A (fi) 1980-04-24
ATE3046T1 (de) 1983-04-15
CA1132542A (en) 1982-09-28
DK439879A (da) 1980-04-24

Similar Documents

Publication Publication Date Title
IE791565L (en) Crop cutting apparatus
ES8107207A1 (es) Procedimiento de preparacion de derivados de tiadiazol
CA2126327A1 (en) Amidino derivatives and their use as nitric oxide synthase inhibitors
ES474288A1 (es) Un procedimiento para la preparacion de derivados del acido 7-oxo-1-aza-biciclo-(3,2,0)-hept-2-en-carboxilico 3 y 6-sus-tituidos
HUT53368A (en) Process for producing pyrazolo-pyridine derivatives and pharmaceutical compositions containing them
MY102919A (en) Pleuromutilin derivatives process for their preparation and their use.
ES8306160A1 (es) "procedimiento para preparar un nuevo compuesto de cefem".
GB1480772A (en) Antibiotic derivatives
EG16630A (en) A process for the preparation of 4-epi erythromycin and derivatives thereof as useful antibacterial agents
DE2965212D1 (en) Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
IL90424A (en) Cephem derivatives, processes for the preparation thereof and pharmaceutical composition containing the same
PL306154A1 (en) Novel derivatives of 9-deoxo-9a-aza-9a-homoerythromycin a, method of obtaining them and pharmaceutic agent containing such derivatives
ES8405006A1 (es) Un procedimiento para la preparacion de derivados del acido tetrahidrofurancarboxilico.
ES8705362A1 (es) Un procedimiento para la preparacion de nuevas aminas terciarias
PH25911A (en) New cephem compounds pharmaceutical composition containing said compounds and method of use thereof
KR890003755A (ko) 7- (2- 메틸- 4- 아미노피롤리디닐)나프티리딘 및 퀴놀린 화합물
ES8200689A1 (es) Un procedimiento para la produccion de analogos de cefalosporina.
IE790754L (en) Substituted ethanolamines
ES473415A1 (es) Un procedimiento para la preparacion de derivados de tiena- micina
ES8105316A1 (es) Procedimiento para preparar la sal de d-diamonio del anti- biotico de oxa-beta-lactama
ES8801291A1 (es) Un procedimiento para la preparacion de nuevos derivados de beta-lactama.
JPS6479192A (en) Moranoline derivative
KR830001305A (ko) 아미노당을 함유하는 폴리엔 마크로라이드 항생제의 유도체와 그 제조방법 및 이를 함유하는 약제학적 조성물
ES304772A1 (es) PROCEDIMIENTO PARA LA PREPARACION DE 10, 11-DIHIDRO-11-OXO-5H-DIBENZO (B, E) (1, 4) DIAZEPINAS BáSICAMENTE SUSTITUIDAS