IL58256A - N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them - Google Patents
N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing themInfo
- Publication number
- IL58256A IL58256A IL58256A IL5825679A IL58256A IL 58256 A IL58256 A IL 58256A IL 58256 A IL58256 A IL 58256A IL 5825679 A IL5825679 A IL 5825679A IL 58256 A IL58256 A IL 58256A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- lower alkyl
- hydrogen
- pyrrolyl
- pyrrol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7838898 | 1978-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL58256A0 IL58256A0 (en) | 1979-12-30 |
| IL58256A true IL58256A (en) | 1984-02-29 |
Family
ID=10500040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL58256A IL58256A (en) | 1978-10-02 | 1979-09-17 | N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0009655B1 (fi) |
| JP (1) | JPS5569577A (fi) |
| AT (1) | ATE3294T1 (fi) |
| AU (1) | AU529482B2 (fi) |
| CA (1) | CA1144165A (fi) |
| DE (1) | DE2965377D1 (fi) |
| DK (1) | DK151803C (fi) |
| ES (1) | ES484616A1 (fi) |
| FI (1) | FI65998C (fi) |
| GR (1) | GR69856B (fi) |
| IE (1) | IE49017B1 (fi) |
| IL (1) | IL58256A (fi) |
| NO (1) | NO151620C (fi) |
| YU (1) | YU41886B (fi) |
| ZA (1) | ZA794923B (fi) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD916552S1 (en) * | 2019-07-26 | 2021-04-20 | Spectrum Diversified Designs, Llc | Trivet |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1150070B (it) * | 1980-12-22 | 1986-12-10 | Lepetit Spa | Procedimento per preparare derivati n-pirrolipiridazinamminici |
| US5254622A (en) * | 1988-12-09 | 1993-10-19 | Asahi Kasei Kogyo Kabushiki Kaisha | ABS resin compositions and molded articles thereof having improved coating performances |
| SG145699A1 (en) * | 2003-07-30 | 2008-09-29 | Xenon Pharmaceuticals Inc | Pyridazine derivatives and their use as therapeutic agents |
| EP2289510A1 (en) | 2004-09-20 | 2011-03-02 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes |
| EP1807085B1 (en) | 2004-09-20 | 2013-08-21 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
| US7829712B2 (en) | 2004-09-20 | 2010-11-09 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-CoA-desaturase |
| CN101084207A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
| AU2005329423A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| MX2007003321A (es) | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como agentes terapeuticos. |
| JP5094398B2 (ja) | 2004-09-20 | 2012-12-12 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環式誘導体およびステアロイル−ＣｏＡデサチュラーゼのメディエータとしてのそれらの使用 |
| CN101208089A (zh) | 2005-06-03 | 2008-06-25 | 泽农医药公司 | 氨基噻唑衍生物作为人硬酯酰-CoA去饱和酶抑制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1168334A (en) * | 1967-01-25 | 1969-10-22 | Lepetit Spa | New Pharmacologically Active Pyridazines |
| GB1378102A (en) * | 1972-03-14 | 1974-12-18 | Lepetit Spa | Antihypertensive compositions |
| GB1408362A (en) * | 1973-05-25 | 1975-10-01 | Lepetit Spa | 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives |
| AU477837B2 (en) * | 1973-05-30 | 1974-12-05 | I. S. F. Sp. A | New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect |
| ES431009A1 (es) * | 1974-05-09 | 1976-10-16 | Isf Spa | Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina. |
-
1979
- 1979-09-07 DE DE7979103326T patent/DE2965377D1/de not_active Expired
- 1979-09-07 AT AT79103326T patent/ATE3294T1/de active
- 1979-09-07 EP EP79103326A patent/EP0009655B1/en not_active Expired
- 1979-09-12 FI FI792832A patent/FI65998C/fi not_active IP Right Cessation
- 1979-09-14 AU AU50866/79A patent/AU529482B2/en not_active Ceased
- 1979-09-17 IL IL58256A patent/IL58256A/xx unknown
- 1979-09-17 ZA ZA00794923A patent/ZA794923B/xx unknown
- 1979-09-24 GR GR60097A patent/GR69856B/el unknown
- 1979-09-25 DK DK400679A patent/DK151803C/da not_active IP Right Cessation
- 1979-09-28 YU YU2374/79A patent/YU41886B/xx unknown
- 1979-10-01 ES ES484616A patent/ES484616A1/es not_active Expired
- 1979-10-01 NO NO793151A patent/NO151620C/no unknown
- 1979-10-01 IE IE1866/79A patent/IE49017B1/en not_active IP Right Cessation
- 1979-10-02 CA CA000336843A patent/CA1144165A/en not_active Expired
- 1979-10-02 JP JP12647779A patent/JPS5569577A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD916552S1 (en) * | 2019-07-26 | 2021-04-20 | Spectrum Diversified Designs, Llc | Trivet |
Also Published As
| Publication number | Publication date |
|---|---|
| FI792832A (fi) | 1980-04-03 |
| YU237479A (en) | 1983-02-28 |
| CA1144165A (en) | 1983-04-05 |
| YU41886B (en) | 1988-02-29 |
| DK151803C (da) | 1988-06-13 |
| IL58256A0 (en) | 1979-12-30 |
| JPH0321553B2 (fi) | 1991-03-22 |
| DK400679A (da) | 1980-04-03 |
| NO151620C (no) | 1985-05-08 |
| IE49017B1 (en) | 1985-07-10 |
| ATE3294T1 (de) | 1983-05-15 |
| ZA794923B (en) | 1980-09-24 |
| DE2965377D1 (en) | 1983-06-16 |
| EP0009655B1 (en) | 1983-05-11 |
| AU5086679A (en) | 1980-04-17 |
| FI65998C (fi) | 1984-08-10 |
| EP0009655A1 (en) | 1980-04-16 |
| NO793151L (no) | 1980-04-08 |
| AU529482B2 (en) | 1983-06-09 |
| DK151803B (da) | 1988-01-04 |
| NO151620B (no) | 1985-01-28 |
| FI65998B (fi) | 1984-04-30 |
| ES484616A1 (es) | 1980-05-16 |
| GR69856B (fi) | 1982-07-19 |
| JPS5569577A (en) | 1980-05-26 |
| IE791866L (en) | 1980-04-02 |
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