IL58229A - Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL58229A
IL58229A IL58229A IL5822979A IL58229A IL 58229 A IL58229 A IL 58229A IL 58229 A IL58229 A IL 58229A IL 5822979 A IL5822979 A IL 5822979A IL 58229 A IL58229 A IL 58229A
Authority
IL
Israel
Prior art keywords
benzofuran
compounds
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL58229A
Other languages
English (en)
Other versions
IL58229A0 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IL58229A0 publication Critical patent/IL58229A0/xx
Publication of IL58229A publication Critical patent/IL58229A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL58229A 1978-09-13 1979-09-11 Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them IL58229A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7836705 1978-09-13

Publications (2)

Publication Number Publication Date
IL58229A0 IL58229A0 (en) 1979-12-30
IL58229A true IL58229A (en) 1984-05-31

Family

ID=10499649

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58229A IL58229A (en) 1978-09-13 1979-09-11 Substituted benzylidene-benzofuran-3-(2h)-one compounds,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (1) USRE32196E (pl)
JP (1) JPS5540692A (pl)
KR (1) KR830001919B1 (pl)
AR (2) AR228020A1 (pl)
AT (1) AT376968B (pl)
AU (1) AU535369B2 (pl)
BG (2) BG43187A3 (pl)
CA (1) CA1202309A (pl)
CH (1) CH644603A5 (pl)
CS (1) CS214806B2 (pl)
DD (1) DD146046A5 (pl)
DK (1) DK382579A (pl)
EG (1) EG14105A (pl)
ES (1) ES484115A1 (pl)
FI (1) FI792850A (pl)
GR (1) GR71200B (pl)
HU (1) HU181450B (pl)
IE (1) IE48824B1 (pl)
IL (1) IL58229A (pl)
IT (1) IT1162395B (pl)
MX (1) MX6232E (pl)
NZ (1) NZ191556A (pl)
PH (1) PH15712A (pl)
PL (1) PL124296B1 (pl)
PT (1) PT70170A (pl)
SE (1) SE447382B (pl)
SU (1) SU1138027A3 (pl)
YU (1) YU222079A (pl)
ZA (1) ZA794836B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307070B1 (en) 1996-01-26 2001-10-23 Phytera, Inc. Substituted aurone derivatives
WO1997026873A1 (en) * 1996-01-26 1997-07-31 Phytera, Inc. Antimicrobial aurone derivatives
JP2001510801A (ja) * 1997-07-25 2001-08-07 フィテラ インク. 置換アウロン誘導体
JP4166433B2 (ja) * 1997-09-11 2008-10-15 第一製薬株式会社 ホルモン依存性疾患治療剤
JP2003524648A (ja) 2000-01-28 2003-08-19 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング ベンゾフラノン誘導体を含む酸化ストレスに対する保護用の配合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT277985B (de) * 1967-11-14 1970-01-12 Schering Ag Verfahren zur Herstellung von neuen Nitro-furan-, -thiophen- oder -pyrrol-derivaten
US4115567A (en) * 1973-12-27 1978-09-19 Carlo Erba S. P. A. 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
US4067993A (en) * 1975-09-24 1978-01-10 Riker Laboratories, Inc. Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids
US4143145A (en) * 1977-01-12 1979-03-06 Carlo Erba S. P. A. Substituted 2-vinyl-chromones and process for their preparation
FR2396756A1 (fr) * 1977-07-06 1979-02-02 Inst Nat Sante Rech Med Nouvelles benzylidene-2-benzofurannones-3, leur obtention et leur application a titre de medicaments
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
US4143055A (en) * 1978-03-27 1979-03-06 Gruppo Lepetit S.P.A. 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives

Also Published As

Publication number Publication date
PH15712A (en) 1983-03-14
MX6232E (es) 1985-01-14
SE7907532L (sv) 1980-03-14
CA1202309A (en) 1986-03-25
CH644603A5 (en) 1984-08-15
GR71200B (pl) 1983-04-11
BG40315A3 (en) 1986-11-14
ZA794836B (en) 1981-03-25
IL58229A0 (en) 1979-12-30
BG43187A3 (en) 1988-04-15
SE447382B (sv) 1986-11-10
AR228020A1 (es) 1983-01-14
KR830001919B1 (ko) 1983-09-23
PL218277A1 (pl) 1980-07-14
DD146046A5 (de) 1981-01-21
PT70170A (en) 1979-10-01
CS214806B2 (en) 1982-06-25
SU1138027A3 (ru) 1985-01-30
IT1162395B (it) 1987-03-25
IT7950245A0 (it) 1979-09-12
AT376968B (de) 1985-01-25
AU535369B2 (en) 1984-03-15
YU222079A (en) 1983-02-28
AR226210A1 (es) 1982-06-15
FI792850A (fi) 1980-03-14
IE48824B1 (en) 1985-05-29
ATA598079A (de) 1984-06-15
AU5078079A (en) 1980-03-20
JPS5540692A (en) 1980-03-22
PL124296B1 (en) 1983-01-31
ES484115A1 (es) 1980-04-16
DK382579A (da) 1980-03-14
USRE32196E (en) 1986-07-01
NZ191556A (en) 1981-03-16
HU181450B (en) 1983-07-28
IE791729L (en) 1980-03-13
EG14105A (en) 1983-03-31

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